Dehydroaripiprazole

7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-1,2-dihydroquinolin-2-one

Formula: C23H25Cl2N3O2 (445.1324)
Chinese Name: 7-[4-[4-(2,3-二氯苯基)-1-哌嗪基]丁氧基]-2(1H)-喹啉酮, 脱氢阿立哌唑
BioDeep ID: BioDeep_00000178018 ( View LC/MS Profile)
SMILES: C1CN(CCN1CCCCOC2=CC3=C(C=C2)C=CC(=O)N3)C4=C(C(=CC=C4)Cl)Cl

Found 3 Sample Hits

m/z Adducts Species Organ Scanning Sample

m/z	Adducts	Species	Organ	Scanning	Sample
463.1582	[M+NH4]+ `PPM:17.3`	Rattus norvegicus	Epididymis	MALDI (DHB)	epik_dhb_head_ito01_04 - MTBLS58 Resolution: 17μm, 178x91 Description
463.1582	[M+NH4]+ `PPM:17.3`	Rattus norvegicus	Epididymis	MALDI (DHB)	epik_dhb_head_ito01_03 - MTBLS58 Resolution: 17μm, 159x110 Description
463.1697	[M+NH4]+ `PPM:7.6`	Mytilus edulis	mantle	MALDI (DHB)	20190201_MS38_Crassostrea_Mantle_350-1500_DHB_pos_A28_10um_270x210 - MTBLS2960 Resolution: 10μm, 270x210 Description

463.1582

[M+NH4]+
PPM:17.3

Rattus norvegicus

Epididymis

MALDI (DHB)

epik_dhb_head_ito01_04 - MTBLS58

Resolution: 17μm, 178x91

Description

463.1582

[M+NH4]+
PPM:17.3

Rattus norvegicus

Epididymis

MALDI (DHB)

epik_dhb_head_ito01_03 - MTBLS58

Resolution: 17μm, 159x110

Description

463.1697

[M+NH4]+
PPM:7.6

Mytilus edulis

mantle

MALDI (DHB)

20190201_MS38_Crassostrea_Mantle_350-1500_DHB_pos_A28_10um_270x210 - MTBLS2960

Resolution: 10μm, 270x210

Description

Dehydroaripiprazole (OPC-14857) is an active metabolite of Aripiprazole. Aripiprazole is an antipsychotic agent and is metabolized by CYP3A4 and CYP2D6 forming mainly Dehydroaripiprazole. Dehydroaripiprazole has with antipsychotic activity equivalent to Aripiprazole[1][2][3].