2-O-Methylascorbic acid

(5R)-5-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-3-methoxy-2,5-dihydrofuran-2-one

Formula: C7H10O6 (190.0477)
Chinese Name: 2-O-甲基抗坏血酸
BioDeep ID: BioDeep_00000169744 ( View LC/MS Profile)
SMILES: [H][C@@]1(OC(=O)C(OC)=C1O)[C@@H](O)CO



Found 5 Sample Hits

m/z Adducts Species Organ Scanning Sample
191.0516 [M+H]+
PPM:17.9
Mus musculus Kidney MALDI (CHCA)
FULL_MS_centriod_CHCA_20210819 - FULL_MS_centriod_CHCA_20210819
Resolution: 17μm, 638x437

Description

AP-MALDI instrument demo test, mass spectrum scan in centroid mode.

191.0556 [M+H]+
PPM:3.1
Homo sapiens esophagus DESI ()
TO31T - MTBLS385
Resolution: 75μm, 56x54

Description

191.0558 [M+H]+
PPM:4.1
Homo sapiens esophagus DESI ()
TO29T - MTBLS385
Resolution: 75μm, 56x48

Description

191.0564 [M+H]+
PPM:7.3
Homo sapiens esophagus DESI ()
LNTO30_7_2 - MTBLS385
Resolution: 75μm, 82x68

Description

191.0547 [M+H]+
PPM:1.6
Mus musculus brain MALDI (DHB)
Brain02_Bregma-3-88 - MTBLS313
Resolution: 17μm, 288x282

Description


2-O-Methylascorbic acid (2-O-MA) is a derivative of vitamin C (ascorbic acid). The enzyme catechol-O-methyltransferase catalyzes the methylation of L-ascorbic acid into 2-O-methylascorbic acid (PMID: 7129800). 2-O-Methylascorbic acid belongs to the class of organic compounds known as butenolides. These are dihydrofurans with a carbonyl group at the C2 carbon atom. 2-O-Methylascorbic acid has been identified in urine and was found to be higher in older women than in younger women (PMID: 28813537).