Desorption electrospray ionisation mass spectrometry imaging of esophageal lymph mode metastases (MTBLS385)

DOI: 10.1158/0008-5472.CAN-16-0699
创建时间: 2025-01-06 16:03:47

Lymph node metastases (LNM) and primary tumour samples were analysed using desorption electrospray ionisation mass spectrometry imaging (DESI MSI). Current assessment of LNM depends on subjective histopathological assessment, whereas analysis by DESI MSI permits an entirely objective assessment. The mass spectral data revealed specific lipidomic patterns across samples, which were shown to correspond to the immunohistochemical image. Statistical prediction of LNM samples was performed using the esophageal adenocarcinoma samples with sensitivity and specificity of 89.5% and 100%, respectively.

人工注释组织解剖术语列表
blank, esophagus, transudate
Cite as:
Nima Abbassi-Ghadi, Ottmar Golf, Sacheen Kumar, Stefan Antonowicz, James S. McKenzie, Juzheng Huang, Nicole Strittmatter, Hiromi Kudo, Emrys A. Jones, Kirill Veselkov, Robert Goldin, Zoltan Takats, George B. Hanna; Imaging of Esophageal Lymph Node Metastases by Desorption Electrospray Ionization Mass Spectrometry. Cancer Res 1 October 2016; 76 (19): 5647–5656. https://doi.org/10.1158/0008-5472.CAN-16-0699

当前项目中的样本列表

LNTO22_1_3

创建时间: 2025-01-06 16:03:47
空间分辨率: 75μm,   121x68
扫描: DESI ()
物种: Homo sapiens (esophagus) - normal

Note

LNTO22_1_4

创建时间: 2025-01-06 16:04:58
空间分辨率: 17μm,   82x80
扫描: DESI ()
物种: Homo sapiens (esophagus) - normal

Note

LNTO22_1_5

创建时间: 2025-01-21 19:51:17
空间分辨率: 75μm,   135x94
扫描: DESI ()
物种: Homo sapiens (esophagus) - normal

Note

LNTO22_1_7

创建时间: 2025-01-21 19:58:21
空间分辨率: 75μm,   69x54
扫描: DESI ()
物种: Homo sapiens (esophagus) - normal

Note

LNTO22_1_8

创建时间: 2025-01-21 20:26:44
空间分辨率: 75μm,   69x61
扫描: DESI ()
物种: Homo sapiens (esophagus) - normal

Note

LNTO22_1_9

创建时间: 2025-01-08 15:26:29
空间分辨率: 75μm,   89x74
扫描: DESI ()
物种: Homo sapiens (esophagus) - normal

Note

LNTO22_2_1

创建时间: 2025-01-21 20:33:05
空间分辨率: 75μm,   89x88
扫描: DESI ()
物种: Homo sapiens (esophagus) - normal

Note

LNTO22_2_2

创建时间: 2025-01-21 21:12:08
空间分辨率: 75μm,   135x94
扫描: DESI ()
物种: Homo sapiens (esophagus) - normal

Note

LNTO26_16_1

创建时间: 2025-01-21 21:15:55
空间分辨率: 75μm,   95x88
扫描: DESI ()
物种: Homo sapiens (esophagus) - normal

Note

LNTO26_7_1

创建时间: 2025-01-20 17:49:57
空间分辨率: 17μm,   75x74
扫描: DESI ()
物种: Homo sapiens (esophagus) - normal

Note

LNTO26_7_2

创建时间: 2025-01-20 17:51:27
空间分辨率: 17μm,   135x101
扫描: DESI ()
物种: Homo sapiens (esophagus) - normal

Note

LNTO26_7_3

创建时间: 2025-01-20 17:53:08
空间分辨率: 75μm,   82x88
扫描: DESI ()
物种: Homo sapiens (esophagus) - normal

Note

LNTO29_16_2

创建时间: 2025-01-07 09:07:14
空间分辨率: 17μm,   95x101
扫描: DESI ()
物种: Homo sapiens (esophagus) - normal

Note

LNTO29_16_3

创建时间: 2025-01-20 17:44:32
空间分辨率: 17μm,   108x107
扫描: DESI ()
物种: Homo sapiens (esophagus) - normal

Note

LNTO29_18_2

创建时间: 2025-01-21 21:18:22
空间分辨率: 75μm,   62x68
扫描: DESI ()
物种: Homo sapiens (esophagus) - normal

Note