Ribose-1-arsenate

Found 10 Sample Hits

m/z	Adducts	Species	Organ	Scanning	Sample
274.9766	[M+H]+ PPM:8.5	Marker Pen	NA	DESI (None)	3ul_0.8Mpa_RAW_20241016-PAPER PNMK - MEMI_test Resolution: 30μm, 315x42 Description By writing the four English letters “PNMK” on white paper with a marker pen, and then scanning with a DESI ion source to obtain the scanning result. The signal of the chemical substances on the marker pen used appears on the channel with an m/z value of 322.1918, 323.1953, 546.4010, and etc, from the single cell deconvolution sampling layer class_4. This test data was tested by chuxiaoping from PANOMIX’s R&D laboratory.
238.9511	[M+H-2H2O]+ PPM:8.5	Plant	Root	MALDI (DHB)	MPIMM_035_QE_P_PO_6pm - MPIMM_035_QE_P_PO_6pm Resolution: 30μm, 165x170 Description
256.9615	[M+H-H2O]+ PPM:8.6	Homo sapiens	esophagus	DESI ()	LNTO22_1_9 - MTBLS385 Resolution: 75μm, 89x74 Description
296.954	[M+Na]+ PPM:7.4	Homo sapiens	esophagus	DESI ()	LNTO22_1_9 - MTBLS385 Resolution: 75μm, 89x74 Description
256.9613	[M+H-H2O]+ PPM:9.3	Homo sapiens	esophagus	DESI ()	LNTO22_1_7 - MTBLS385 Resolution: 75μm, 69x54 Description
296.9537	[M+Na]+ PPM:8.4	Homo sapiens	esophagus	DESI ()	LNTO22_1_7 - MTBLS385 Resolution: 75μm, 69x54 Description
274.9741	[M+H]+ PPM:0.6	Homo sapiens	esophagus	DESI ()	LNTO22_1_8 - MTBLS385 Resolution: 75μm, 69x61 Description
273.9644	[M]+ PPM:7.4	Mus musculus	brain	MALDI (DHB)	Brain01_Bregma-3-88b_centroid - MTBLS313 Resolution: 17μm, 265x320 Description
273.9638	[M]+ PPM:9.6	Mus musculus	brain	MALDI (DHB)	Brain02_Bregma1-42_03 - MTBLS313 Resolution: 17μm, 483x403 Description
273.9638	[M]+ PPM:9.6	Mus musculus	brain	MALDI (DHB)	Brain02_Bregma-1-46 - MTBLS313 Resolution: 17μm, 294x399 Description

Ribose-1-arsenate is an intermediate in arsenate detoxification I pathway. Arsenic detoxification in most mammals involves alternative steps of reduction and oxidative methylation. The end metabolites are methylarsonate,cacodylate, and dimethylarsinous acid,which are less reactive than arsenate and arsenite, and are excreted in the urine.The pathway starts with the reduction of arsenate to arsenite. In this process,arsenate can be conjugate to ribose by the enzyme purine nucleoside phosphorylase (PNP), which accepts arsenate as an alternative substrate to its normal substrate, phosphate. The ribose-1-arsenate thus formed is converted to arsenite in the presence of dihydrolipoate, in a process that has not been fully characterized yet. [HMDB]. Ribose-1-arsenate is found in many foods, some of which are japanese walnut, yam, black-eyed pea, and lovage. Ribose-1-arsenate is an intermediate in arsenate detoxification I pathway. Arsenic detoxification in most mammals involves alternative steps of reduction and oxidative methylation. The end metabolites are methylarsonate,cacodylate, and dimethylarsinous acid,which are less reactive than arsenate and arsenite, and are excreted in the urine.The pathway starts with the reduction of arsenate to arsenite. In this process,arsenate can be conjugate to ribose by the enzyme purine nucleoside phosphorylase (PNP), which accepts arsenate as an alternative substrate to its normal substrate, phosphate. The ribose-1-arsenate thus formed is converted to arsenite in the presence of dihydrolipoate, in a process that has not been fully characterized yet.