ST 18:4;O3

3,16alpha-dihydroxy-1,3,5(10)-estratrien-17-one

Formula: C18H22O3 (286.1569)
Chinese Name: 4-羟雌甾酮, 16α-羟基雌酮, 2-羟基雌酮
BioDeep ID: BioDeep_00000637483 ( View LC/MS Profile)
SMILES: [C@@]12([H])CCC3C=C(O)C=CC=3[C@@]1([H])CC[C@]1(C)[C@@H](O)C(=O)C[C@@]21[H]



Found 6 Sample Hits

m/z Adducts Species Organ Scanning Sample
287.1657 [M+H]+
PPM:5.4		 Homo sapiens esophagus DESI ()
LNTO22_1_3 - MTBLS385
Resolution: 75μm, 121x68

Description

287.1656 [M+H]+
PPM:5		 Homo sapiens esophagus DESI ()
LNTO29_16_2 - MTBLS385
Resolution: 17μm, 95x101

Description

287.1661 [M+H]+
PPM:6.7		 Homo sapiens esophagus DESI ()
LNTO22_1_9 - MTBLS385
Resolution: 75μm, 89x74

Description

287.166 [M+H]+
PPM:6.4		 Homo sapiens esophagus DESI ()
LNTO22_1_5 - MTBLS385
Resolution: 75μm, 135x94

Description

287.1658 [M+H]+
PPM:5.7		 Homo sapiens esophagus DESI ()
LNTO22_1_7 - MTBLS385
Resolution: 75μm, 69x54

Description

287.1652 [M+H]+
PPM:3.6		 Homo sapiens esophagus DESI ()
LNTO22_1_8 - MTBLS385
Resolution: 75μm, 69x61

Description


D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C483 - Therapeutic Estrogen D020011 - Protective Agents > D016588 - Anticarcinogenic Agents D000970 - Antineoplastic Agents 4-Hydroxyestrone (4-OHE1), an estrone metabolite, has strong neuroprotective effect against oxidative neurotoxicity. 4-Hydroxyestrone increases cytoplasmic translocation of p53 resulting from SIRT1-mediated deacetylation of p53. 4-Hydroxyestrone has little estrogenic activity[1].