Pipamperone

1-[4-(4-fluorophenyl)-4-oxobutyl]-[1,4-bipiperidine]-4-carboxamide

Formula: C21H30FN3O2 (375.2322)
Chinese Name: 匹泮哌隆
BioDeep ID: BioDeep_00000182445 ( View LC/MS Profile)
SMILES: C1CCN(CC1)C2(CCN(CC2)CCCC(=O)C3=CC=C(C=C3)F)C(=O)N

Found 3 Sample Hits

m/z Adducts Species Organ Scanning Sample

m/z	Adducts	Species	Organ	Scanning	Sample
376.2346	[M+H]+ `PPM:12.9`	Homo sapiens	esophagus	DESI ()	LNTO22_1_3 - MTBLS385 Resolution: 75μm, 121x68 Description
393.2656	[M+NH4]+ `PPM:1.1`	Homo sapiens	colorectal adenocarcinoma	DESI ()	80TopL, 50TopR, 70BottomL, 60BottomR-profile - MTBLS415 Resolution: 17μm, 137x136 Description The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024).
376.235	[M+H]+ `PPM:11.9`	Homo sapiens	esophagus	DESI ()	LNTO22_2_2 - MTBLS385 Resolution: 75μm, 135x94 Description

376.2346

[M+H]+
PPM:12.9

Homo sapiens

esophagus

DESI ()

LNTO22_1_3 - MTBLS385

Resolution: 75μm, 121x68

Description

393.2656

[M+NH4]+
PPM:1.1

Homo sapiens

colorectal adenocarcinoma

DESI ()

80TopL, 50TopR, 70BottomL, 60BottomR-profile - MTBLS415

Resolution: 17μm, 137x136

Description

The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024).

376.235

[M+H]+
PPM:11.9

Homo sapiens

esophagus

DESI ()

LNTO22_2_2 - MTBLS385

Resolution: 75μm, 135x94

Description

D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014150 - Antipsychotic Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents N - Nervous system > N05 - Psycholeptics > N05A - Antipsychotics > N05AD - Butyrophenone derivatives D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D012702 - Serotonin Antagonists D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent Pipamperone (Floropipamide; McN-JR 3345; R 3345) is a high-affinity antagonist of 5-HT2A receptor (pKi=8.2) and D4 receptor (pKi=8.0) and a low-affinity antagonist of D2 receptor (pKi=6.7)[1].