O-Desmethylvenlafaxine glucuronide

(2S,3S,4S,5R,6S)-6-{4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenoxy}-3,4,5-trihydroxyoxane-2-carboxylic acid

Formula: C22H33NO8 (439.2206)
Chinese Name: rac-O-去甲基文拉法辛-β-D-葡萄糖醛酸
BioDeep ID: BioDeep_00000054531 ( View LC/MS Profile)
SMILES: CN(C)CC(C1=CC=C(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)C=C1)C1(O)CCCCC1

Found 2 Sample Hits

m/z Adducts Species Organ Scanning Sample

m/z	Adducts	Species	Organ	Scanning	Sample
440.2296	[M+H]+ `PPM:3.9`	Homo sapiens	esophagus	DESI ()	LNTO22_1_3 - MTBLS385 Resolution: 75μm, 121x68 Description
440.2298	[M+H]+ `PPM:4.4`	Homo sapiens	esophagus	DESI ()	LNTO22_1_8 - MTBLS385 Resolution: 75μm, 69x61 Description

440.2296

[M+H]+
PPM:3.9

Homo sapiens

esophagus

DESI ()

LNTO22_1_3 - MTBLS385

Resolution: 75μm, 121x68

Description

440.2298

[M+H]+
PPM:4.4

Homo sapiens

esophagus

DESI ()

LNTO22_1_8 - MTBLS385

Resolution: 75μm, 69x61

Description

O-Desmethylvenlafaxine glucuronide is a metabolite of venlafaxine (brand name: Effexor or Efexor). Venlafaxine is a bicyclic antidepressant and is usually categorized as a serotonin-norepinephrine reuptake inhibitor (SNRI), but it has been referred to as a serotonin-norepinephrine-dopamine reuptake inhibitor. It works by blocking the transporter reuptake proteins for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse.