4R-Hydroxy solifenacin

1-azabicyclo[2.2.2]octan-3-yl (1S,4R)-4-hydroxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate

Formula: C23H26N2O3 (378.1943)
Chinese Name:
BioDeep ID: BioDeep_00000054494 ( View LC/MS Profile)
SMILES: [H][C@]12CCN(CC1)CC2OC(=O)N1C[C@H](O)C2=C(C=CC=C2)[C@@H]1C1=CC=CC=C1

Found 3 Sample Hits

m/z Adducts Species Organ Scanning Sample

m/z	Adducts	Species	Organ	Scanning	Sample
417.2956	[M+K]+ `PPM:8.4`	Rattus norvegicus	Epididymis	MALDI (DHB)	epik_dhb_head_ito08_44 - MTBLS58 Resolution: 17μm, 299x111 Description
417.2961	[M+K]+ `PPM:9.6`	Rattus norvegicus	Epididymis	MALDI (DHB)	epik_dhb_head_ito08_46 - MTBLS58 Resolution: 17μm, 298x106 Description
417.2962	[M+K]+ `PPM:9.9`	Rattus norvegicus	Epididymis	MALDI (DHB)	epik_dhb_head_ito08_48 - MTBLS58 Resolution: 17μm, 294x107 Description

417.2956

[M+K]+
PPM:8.4

Rattus norvegicus

Epididymis

MALDI (DHB)

epik_dhb_head_ito08_44 - MTBLS58

Resolution: 17μm, 299x111

Description

417.2961

[M+K]+
PPM:9.6

Rattus norvegicus

Epididymis

MALDI (DHB)

epik_dhb_head_ito08_46 - MTBLS58

Resolution: 17μm, 298x106

Description

417.2962

[M+K]+
PPM:9.9

Rattus norvegicus

Epididymis

MALDI (DHB)

epik_dhb_head_ito08_48 - MTBLS58

Resolution: 17μm, 294x107

Description

4R-Hydroxy solifenacin is a metabolite of solifenacin. Solifenacin (trade name Vesicare) is a urinary antispasmodic of the antimuscarinic class. It is used in the treatment of overactive bladder with or without urge incontinence. It is manufactured by Astellas and co-marketed by Astellas and GlaxoSmithKline. (Wikipedia)