Lamotrigine

6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine

Formula: C9H7Cl2N5 (255.0078)
Chinese Name: 拉莫三嗪
BioDeep ID: BioDeep_00000017850 ( View LC/MS Profile)
SMILES: C1=CC(=C(C(=C1)Cl)Cl)C2=C(N=C(N=N2)N)N



Found 4 Sample Hits

m/z Adducts Species Organ Scanning Sample
256.013 [M+H]+
PPM:8.3
Plant Root MALDI (DHB)
MPIMM_035_QE_P_PO_6pm - MPIMM_035_QE_P_PO_6pm
Resolution: 30μm, 165x170

Description

277.9953 [M+Na]+
PPM:6.4
Plant Root MALDI (DHB)
MPIMM_035_QE_P_PO_6pm - MPIMM_035_QE_P_PO_6pm
Resolution: 30μm, 165x170

Description

255.0067 [M]+
PPM:2.4
Homo sapiens esophagus DESI ()
TO31T - MTBLS385
Resolution: 75μm, 56x54

Description

255.0069 [M]+
PPM:1.6
Homo sapiens esophagus DESI ()
LNTO30_7_2 - MTBLS385
Resolution: 75μm, 82x68

Description


Lamotrigine is an anticonvulsant drug used in the treatment of epilepsy and bipolar disorder. For epilepsy it is used to treat partial seizures, primary and secondary tonic-clonic seizures, and seizures associated with Lennox-Gastaut syndrome. Lamotrigine also acts as a mood stabilizer. It is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. Chemically unrelated to other anticonvulsants, lamotrigine has relatively few side-effects and does not require blood monitoring. The exact way lamotrigine works is unknown. [Wikipedia] D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014150 - Antipsychotic Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers D002491 - Central Nervous System Agents > D000927 - Anticonvulsants D002317 - Cardiovascular Agents > D026941 - Sodium Channel Blockers N - Nervous system > N03 - Antiepileptics > N03A - Antiepileptics D000077264 - Calcium-Regulating Hormones and Agents D049990 - Membrane Transport Modulators