Amrinone

3-amino-5-(pyridin-4-yl)-1,2-dihydropyridin-2-one

Formula: C10H9N3O (187.0746)
Chinese Name: 氨力农, 安乃近
BioDeep ID: BioDeep_00000014671 ( View LC/MS Profile)
SMILES: NC1=CC(=CNC1=O)C1=CC=NC=C1

Found 1 Sample Hits

m/z Adducts Species Organ Scanning Sample

m/z	Adducts	Species	Organ	Scanning	Sample
188.0824	[M+H]+ `PPM:3`	Homo sapiens	esophagus	DESI ()	LNTO22_1_4 - MTBLS385 Resolution: 17μm, 82x80 Description

188.0824

[M+H]+
PPM:3

Homo sapiens

esophagus

DESI ()

LNTO22_1_4 - MTBLS385

Resolution: 17μm, 82x80

Description

Amrinone is only found in individuals that have used or taken this drug. It is a type 3 pyridine phosphodiesterase inhibitor. It is used in the treatment of congestive heart failure.Amrinone is a phosphodiesterase inhibitor (PDE3), resulting in increased cAMP and cGMP which leads to an increase in the calcium influx like that caused by beta-agonists resulting in increased inotropic effect.