5-Amino-6-(5'-phosphoribitylamino)uracil

{[(2R,3S,4S)-5-[(5-amino-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino]-2,3,4-trihydroxypentyl]oxy}phosphonic acid

Formula: C9H17N4O9P (356.0733)
Chinese Name:
BioDeep ID: BioDeep_00000007784 ( View LC/MS Profile)
SMILES: NC1=C(NC[C@H](O)[C@H](O)[C@H](O)COP(O)(O)=O)NC(=O)NC1=O



Found 3 Sample Hits

m/z Adducts Species Organ Scanning Sample
357.0837 [M+H]+
PPM:8.7		 Mus musculus Kidney MALDI (CHCA)
FULL_MS_centriod_CHCA_20210819 - FULL_MS_centriod_CHCA_20210819
Resolution: 17μm, 638x437

Description

AP-MALDI instrument demo test, mass spectrum scan in centroid mode.
357.0754 [M+H]+
PPM:14.5		 Mytilus edulis mantle MALDI (DHB)
20190201_MS38_Crassostrea_Mantle_350-1500_DHB_pos_A28_10um_270x210 - MTBLS2960
Resolution: 10μm, 270x210

Description

357.0743 [M+H]+
PPM:17.6		 Mytilus edulis mantle MALDI (DHB)
20190216_MS38_Mytilus_mantle_350-1500_DHB_pos_A26_10um_275x210 - MTBLS2960
Resolution: 10μm, 275x210

Description


5-Amino-6-(5-phosphoribitylamino)uracil belongs to the class of organic compounds known as monosaccharide phosphates. These are monosaccharides comprising a phosphated group linked to the carbohydrate unit. 5-Amino-6-(5-phosphoribitylamino)uracil is an extremely weak basic (essentially neutral) compound (based on its pKa). 5-Amino-6-(5-phosphoribitylamino)uracil has been detected, but not quantified in, several different foods, such as sapodilla, kumquats, sacred lotus, Persian limes, and Cascade huckleberries. This could make 5-amino-6-(5-phosphoribitylamino)uracil a potential biomarker for the consumption of these foods. 5-Amino-6-(5-phosphoribitylamino)uracil is an intermediate in riboflavin metabolism. 5-Amino-6-(5-phosphoribitylamino)uracil is the third to last step in the synthesis of 7-hydroxy-6-methyl-8-ribityl lumazine and is converted from 5-amino-6-(5-phosphoribosylamino)uracil via the enzyme 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193). It is then converted into 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine via a hydrolase enzyme (EC 3.1.3.- ). 5-amino-6-(5-phospho-d-ribitylamino)uracil is a member of the class of compounds known as monosaccharide phosphates. Monosaccharide phosphates are monosaccharides comprising a phosphated group linked to the carbohydrate unit. 5-amino-6-(5-phospho-d-ribitylamino)uracil is slightly soluble (in water) and a moderately acidic compound (based on its pKa). 5-amino-6-(5-phospho-d-ribitylamino)uracil can be found in a number of food items such as star fruit, chinese cabbage, mamey sapote, and sapodilla, which makes 5-amino-6-(5-phospho-d-ribitylamino)uracil a potential biomarker for the consumption of these food products. 5-amino-6-(5-phospho-d-ribitylamino)uracil exists in E.coli (prokaryote) and yeast (eukaryote).