Anisatin

(1S,2R,3S,4R,5R,7R,8R,11R)-4,5,7,11-tetrahydroxy-2,7-dimethyl-9-oxaspiro[oxetane-3,6-tricyclo[6.3.1.0¹,⁵]dodecane]-4,10-dione

Formula: C15H20O8 (328.1158)
Chinese Name: 莽草毒素
BioDeep ID: BioDeep_00000007276 ( View LC/MS Profile)
SMILES: C[C@@H]1C[C@@H](O)[C@]2(O)[C@]3(COC3=O)[C@@](C)(O)[C@H]3C[C@@]12[C@@H](O)C(=O)O3



Found 4 Sample Hits

m/z Adducts Species Organ Scanning Sample
329.1172 [M+H]+
PPM:17.9		 Posidonia oceanica root MALDI (CHCA)
20190613_MS1_A19r-18 - MTBLS1746
Resolution: 17μm, 246x264

Description

329.1171 [M+H]+
PPM:18.2		 Posidonia oceanica root MALDI (CHCA)
MS1_20180404_PO_1200 - MTBLS1746
Resolution: 17μm, 193x208

Description

329.1277 [M+H]+
PPM:14		 Homo sapiens esophagus DESI ()
LNTO22_1_4 - MTBLS385
Resolution: 17μm, 82x80

Description

329.1191 [M+H]+
PPM:12.1		 Homo sapiens esophagus DESI ()
LNTO22_1_5 - MTBLS385
Resolution: 75μm, 135x94

Description


ANIASATIN, also known as shikimin, is a member of the class of compounds known as terpene lactones. Terpene lactones are prenol lipids containing a lactone ring. ANIASATIN is soluble (in water) and a very weakly acidic compound (based on its pKa). Anisatin, a pure toxic substance isolated from the seeds of a Japanese plant (Illicium anisatum) acts as a picrotoxin-like, non-competitive GABA antagonist. Anisatin suppresses GABA-induced currents in a concentration-dependent manner with an EC50 of ~1.10?μM[1]. Anisatin, a pure toxic substance isolated from the seeds of a Japanese plant (Illicium anisatum) acts as a picrotoxin-like, non-competitive GABA antagonist. Anisatin suppresses GABA-induced currents in a concentration-dependent manner with an EC50 of ~1.10?μM[1].