Triclosan

5-Chloro-2-(2,4-dichloro-phenoxy)-phenol

Formula: C12H7Cl3O2 (287.9512)
Chinese Name: 5-氯-2-(2,4-二氯苯氧基)苯酚, 三氯生
BioDeep ID: BioDeep_00000002212 ( View LC/MS Profile)
SMILES: C1=CC(=C(C=C1Cl)O)OC2=C(C=C(C=C2)Cl)Cl



Found 13 Sample Hits

m/z Adducts Species Organ Scanning Sample
305.99 [M+NH4]+
PPM:16.4
Plant Root MALDI (DHB)
MPIMM_035_QE_P_PO_6pm - MPIMM_035_QE_P_PO_6pm
Resolution: 30μm, 165x170

Description

252.9374 [M+H-2H2O]+
PPM:0.4
Homo sapiens esophagus DESI ()
LNTO29_16_2 - MTBLS385
Resolution: 17μm, 95x101

Description

252.9366 [M+H-2H2O]+
PPM:2.8
Homo sapiens esophagus DESI ()
TO42T - MTBLS385
Resolution: 17μm, 69x81

Description

252.9368 [M+H-2H2O]+
PPM:2
Homo sapiens esophagus DESI ()
LNTO22_1_9 - MTBLS385
Resolution: 75μm, 89x74

Description

287.9753 [M-H2O+NH4]+
PPM:3.1
Homo sapiens colorectal adenocarcinoma DESI ()
80TopL, 50TopR, 70BottomL, 60BottomR-profile - MTBLS415
Resolution: 17μm, 137x136

Description

The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024).

252.9384 [M+H-2H2O]+
PPM:4.3
Homo sapiens colorectal adenocarcinoma DESI ()
520TopL, 490TopR, 510BottomL, 500BottomR-profile - MTBLS415
Resolution: 17μm, 147x131

Description

The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024).

252.9374 [M+H-2H2O]+
PPM:0.4
Homo sapiens esophagus DESI ()
LNTO29_16_3 - MTBLS385
Resolution: 17μm, 108x107

Description

252.9376 [M+H-2H2O]+
PPM:1.2
Homo sapiens esophagus DESI ()
TO31T - MTBLS385
Resolution: 75μm, 56x54

Description

252.9363 [M+H-2H2O]+
PPM:4
Homo sapiens esophagus DESI ()
LNTO22_1_7 - MTBLS385
Resolution: 75μm, 69x54

Description

310.9426 [M+Na]+
PPM:7.1
Homo sapiens esophagus DESI ()
LNTO22_1_7 - MTBLS385
Resolution: 75μm, 69x54

Description

252.9371 [M+H-2H2O]+
PPM:0.8
Homo sapiens esophagus DESI ()
LNTO22_1_8 - MTBLS385
Resolution: 75μm, 69x61

Description

288.9539 [M+H]+
PPM:15.7
Homo sapiens esophagus DESI ()
LNTO22_2_2 - MTBLS385
Resolution: 75μm, 135x94

Description

252.9374 [M+H-2H2O]+
PPM:0.4
Homo sapiens colorectal adenocarcinoma DESI ()
240TopL, 210TopR, 230BottomL, 220BottomR-centroid - MTBLS176
Resolution: 50μm, 142x141

Description


Triclosan is an antibacterial and antifungal agent. It is a polychloro phenoxy phenol. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes. According to the Food and Drug Administration (FDA) at the present time there is no evidence that triclosan in personal care products provides an extra benefit to health beyond its anti-gingivitis effect in toothpaste. The FDA does not recommend changing consumer use of triclosan containing products one way or the other due to currently insufficient safety evidence. Studies by the Environmental Protection Agency (EPA) found triclosan to be an effective antibacterial. Triclosan safety is currently under review by the FDA and Health Canada. Triclosan is only found in individuals that have used or taken this drug. D - Dermatologicals > D08 - Antiseptics and disinfectants > D08A - Antiseptics and disinfectants > D08AE - Phenol and derivatives D - Dermatologicals > D09 - Medicated dressings > D09A - Medicated dressings > D09AA - Medicated dressings with antiinfectives D000963 - Antimetabolites > D000960 - Hypolipidemic Agents > D054872 - Fatty Acid Synthesis Inhibitors D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 8632 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 8246 CONFIDENCE standard compound; EAWAG_UCHEM_ID 168 D009676 - Noxae > D000963 - Antimetabolites D000890 - Anti-Infective Agents C254 - Anti-Infective Agent