M/Z: 964.4798
Hit 3 annotations: PGP(a-17:0/LTE4)_[M+H-2H2O]+; CDP-DG(i-12:0/20:3(6,8,11)-OH(5))_[M+H]+; CDP-DG(18:3(9Z,12Z,15Z)/18:2(9Z,12Z))_[M+H-2H2O]+
- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。
Found 17 Reference Ions Near m/z 964.4798
| NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
|---|---|---|---|---|---|
| MSI_000020875 Reliable | 964.4757 | 964.4752 ~ 964.4759 MzDiff: 2.9 ppm |
PGP(a-17:0/LTE4) (BioDeep_00000199503) Formula: C46H83NO16P2S (999.4908) |
9 (53%) | Rattus norvegicus [UBERON:0004358] caput epididymis |
| MSI_000063158 Reliable | 964.4797 | 964.4796 ~ 964.4798 MzDiff: 0.8 ppm |
CDP-DG(18:3(9Z,12Z,15Z)/18:2(9Z,12Z)) (BioDeep_00000108334) Formula: C48H79N3O15P2 (999.4986) |
0.7 (100%) | Mus musculus [UBERON:0000956] cerebral cortex |
| MSI_000006792 | 964.4766 | 964.4766 ~ 964.4766 MzDiff: none |
PGP(a-17:0/LTE4) (BioDeep_00000199503) Formula: C46H83NO16P2S (999.4908) |
2.68 (100%) | Rattus norvegicus [UBERON:0004358] caput epididymis |
| MSI_000061176 Unreliable | 964.4765 | 964.4762 ~ 964.4767 MzDiff: 2.0 ppm |
CDP-DG(18:3(9Z,12Z,15Z)/18:2(9Z,12Z)) (BioDeep_00000108334) Formula: C48H79N3O15P2 (999.4986) |
2.51 (67%) | Mus musculus [UBERON:0000956] cerebral cortex |
| MSI_000021409 Unreliable | 964.4799 | 964.4799 ~ 964.4799 MzDiff: none |
CDP-DG(i-12:0/20:3(6,8,11)-OH(5)) (BioDeep_00000218352) Formula: C44H75N3O16P2 (963.4622) |
0.97 (100%) | Mus musculus [UBERON:0001499] muscle of arm |
| MSI_000002399 Unreliable | 964.48 | 964.48 ~ 964.48 MzDiff: none |
PGP(a-17:0/LTE4) (BioDeep_00000199503) Formula: C46H83NO16P2S (999.4908) |
1.87 (100%) | Rattus norvegicus [UBERON:0001950] neocortex |
| MSI_000002457 Unreliable | 964.4853 | 964.4853 ~ 964.4853 MzDiff: none |
CDP-DG(18:3(9Z,12Z,15Z)/18:2(9Z,12Z)) (BioDeep_00000108334) Formula: C48H79N3O15P2 (999.4986) |
1.14 (100%) | Rattus norvegicus [UBERON:0001950] neocortex |
| MSI_000003244 Unreliable | 964.48 | 964.48 ~ 964.48 MzDiff: none |
PGP(a-17:0/LTE4) (BioDeep_00000199503) Formula: C46H83NO16P2S (999.4908) |
0.51 (100%) | Rattus norvegicus [UBERON:0002037] cerebellum |
| MSI_000003309 Unavailable | 964.4853 | 964.4853 ~ 964.4853 MzDiff: none |
CDP-DG(18:3(9Z,12Z,15Z)/18:2(9Z,12Z)) (BioDeep_00000108334) Formula: C48H79N3O15P2 (999.4986) |
-0.18 (100%) | Rattus norvegicus [UBERON:0002037] cerebellum |
| MSI_000005343 Unavailable | 964.48 | 964.48 ~ 964.48 MzDiff: none |
PGP(a-17:0/LTE4) (BioDeep_00000199503) Formula: C46H83NO16P2S (999.4908) |
-1.07 (100%) | Rattus norvegicus [UBERON:0002298] brainstem |
| MSI_000005373 Unavailable | 964.4853 | 964.4853 ~ 964.4853 MzDiff: none |
CDP-DG(18:3(9Z,12Z,15Z)/18:2(9Z,12Z)) (BioDeep_00000108334) Formula: C48H79N3O15P2 (999.4986) |
-1.58 (100%) | Rattus norvegicus [UBERON:0002298] brainstem |
| MSI_000005605 Unreliable | 964.4853 | 964.4853 ~ 964.4853 MzDiff: none |
CDP-DG(18:3(9Z,12Z,15Z)/18:2(9Z,12Z)) (BioDeep_00000108334) Formula: C48H79N3O15P2 (999.4986) |
0.03 (100%) | Rattus norvegicus [UBERON:0002435] striatum |
| MSI_000005854 Unavailable | 964.48 | 964.48 ~ 964.48 MzDiff: none |
PGP(a-17:0/LTE4) (BioDeep_00000199503) Formula: C46H83NO16P2S (999.4908) |
-0.75 (100%) | Rattus norvegicus [UBERON:0002435] striatum |
| MSI_000025190 Unreliable | 964.4852 | 964.4852 ~ 964.4852 MzDiff: none |
PGP(20:4(5Z,8Z,11Z,14Z)/6 keto-PGF1alpha) (BioDeep_00000198666) Formula: C46H78O17P2 (964.4714) |
1.7 (100%) | Mus musculus [UBERON:0004269] upper arm connective tissue |
| MSI_000058841 Unreliable | 964.4787 | 964.4787 ~ 964.4787 MzDiff: none |
CDP-DG(18:3(9Z,12Z,15Z)/18:2(9Z,12Z)) (BioDeep_00000108334) Formula: C48H79N3O15P2 (999.4986) |
0.04 (100%) | Mus musculus [UBERON:0001950] neocortex |
| MSI_000060128 Unavailable | 964.4787 | 964.4787 ~ 964.4787 MzDiff: none |
CDP-DG(18:3(9Z,12Z,15Z)/18:2(9Z,12Z)) (BioDeep_00000108334) Formula: C48H79N3O15P2 (999.4986) |
-1.02 (100%) | Mus musculus [UBERON:0002298] brainstem |
| MSI_000060278 Unreliable | 964.4787 | 964.4787 ~ 964.4787 MzDiff: none |
CDP-DG(18:3(9Z,12Z,15Z)/18:2(9Z,12Z)) (BioDeep_00000108334) Formula: C48H79N3O15P2 (999.4986) |
0.98 (100%) | Mus musculus [UBERON:0002421] hippocampal formation |
Found 8 Sample Hits
| Metabolite | Species | Sample | |
|---|---|---|---|
| PGP(a-17:0/LTE4) Formula: C46H83NO16P2S (999.4908) Adducts: [M+H-2H2O]+ (Ppm: 3.2) |
Rattus norvegicus (Brain) |
Spectroswiss - sol_2x_br_2Resolution: 17μm, 488x193
|
|
| CDP-DG(i-12:0/20:3(6,8,11)-OH(5)) Formula: C44H75N3O16P2 (963.4622) Adducts: [M+H]+ (Ppm: 10.8) |
Mus musculus (Left upper arm) |
357_l_total ion countResolution: 50μm, 97x131
Diseased |
|
| CDP-DG(i-12:0/20:3(6,8,11)-OH(5)) Formula: C44H75N3O16P2 (963.4622) Adducts: [M+H]+ (Ppm: 5.7) |
Mus musculus (Lung) |
image3Resolution: 40μm, 146x190
Fig. 4 MALDI-MSI data of mouse lung tissue after administration with D9-choline and U13C-DPPC–containing Poractant alfa surfactant (labels administered 12 h prior to tissue collection). Ion images of (A) m/z 796.6856 ([U13C-DPPC+Na]+), (B) m/z 756.5154 [PC32:0+Na]+), and (C) m/z 765.6079 ([D9-PC32:0+Na]+). D: Overlay image of [U13C-PC32:0+Na]+ (red) and [D9-PC32:0+Na]+ (green). Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. MSI, mass spectrometry imaging; PC, phosphatidylcholine; U13C-DPPC, universally 13C-labeled dipalmitoyl PC. |
|
| CDP-DG(i-12:0/20:3(6,8,11)-OH(5)) Formula: C44H75N3O16P2 (963.4622) Adducts: [M+H]+ (Ppm: 5.7) |
Mus musculus (Lung) |
image5Resolution: 40μm, 163x183
Supplementary Figure S8. MALDI-MSI data of mouse lung tissue administered with D9-choline and
U 13C-DPPC–containing Poractant alfa surfactant (labels administered 18 h prior to sacrifice). Ion
images of (a) m/z 796.6856 ([U13C-DPPC+Na]+), (b) m/z 756.5154 [PC32:0+Na]+ and (c) m/z 765.6079
([D9-PC32:0+Na]+). (d) Overlay image of [U13C-DPPC+Na]+ (red) and [D9-PC32:0+Na]+ (green).
Parts per million (ppm) mass errors are indicated in parentheses. All images were visualised using totalion-current normalisation and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. |
|
| CDP-DG(18:3(9Z,12Z,15Z)/18:2(9Z,12Z)) Formula: C48H79N3O15P2 (999.4986) Adducts: [M+H-2H2O]+ (Ppm: 6.3) |
Mus musculus (brain) |
Brain01_Bregma-3-88b_centroidResolution: 17μm, 265x320
|
|
| CDP-DG(18:3(9Z,12Z,15Z)/18:2(9Z,12Z)) Formula: C48H79N3O15P2 (999.4986) Adducts: [M+H-2H2O]+ (Ppm: 5.4) |
Mus musculus (brain) |
Brain02_Bregma1-42_03Resolution: 17μm, 483x403
|
|
| CDP-DG(18:3(9Z,12Z,15Z)/18:2(9Z,12Z)) Formula: C48H79N3O15P2 (999.4986) Adducts: [M+H-2H2O]+ (Ppm: 5.1) |
Mus musculus (brain) |
Brain02_Bregma-3-88Resolution: 17μm, 288x282
|
|
| CDP-DG(18:3(9Z,12Z,15Z)/18:2(9Z,12Z)) Formula: C48H79N3O15P2 (999.4986) Adducts: [M+H-2H2O]+ (Ppm: 5.2) |
Mus musculus (brain) |
Brain02_Bregma-1-46Resolution: 17μm, 294x399
|
|
