MSI_000013705

Unreliable

排名分数: 0.34
参考来源: Plant (PO:0005417: phloem)

M/z: 310.0234
Mass Window: 310.0234 ~ 310.0234 (none)

参考注释

Lamivudine-monophosphate_[M+H]+ (BioDeep_00000054186)
{[5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy}phosphonic acid

Formula: C8H12N3O6PS (309.01844220000004)
SMILES: C1C(OC(S1)COP(=O)(O)O)N2C=CC(=NC2=O)N

Lamivudine-monophosphate is a metabolite of lamivudine. Lamivudine (2,3-dideoxy-3-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI). It is marketed by GlaxoSmithKline with the brand names Zeffix, Heptovir, Epivir, and Epivir-HBV. Lamivudine has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV. It improves the seroconversion of e-antigen positive hepatitis B and also improves histology staging of the liver. (Wikipedia)