Lamivudine-monophosphate

{[5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy}phosphonic acid

Formula: C8H12N3O6PS (309.0184)
Chinese Name:
BioDeep ID: BioDeep_00000054186 ( View LC/MS Profile)
SMILES: C1C(OC(S1)COP(=O)(O)O)N2C=CC(=NC2=O)N

Found 1 Sample Hits

m/z Adducts Species Organ Scanning Sample

m/z	Adducts	Species	Organ	Scanning	Sample
310.0234	[M+H]+ `PPM:7.5`	Plant	Root	MALDI (DHB)	MPIMM_035_QE_P_PO_6pm - MPIMM_035_QE_P_PO_6pm Resolution: 30μm, 165x170 Description

310.0234

[M+H]+
PPM:7.5

Plant

Root

MALDI (DHB)

MPIMM_035_QE_P_PO_6pm - MPIMM_035_QE_P_PO_6pm

Resolution: 30μm, 165x170

Description

Lamivudine-monophosphate is a metabolite of lamivudine. Lamivudine (2,3-dideoxy-3-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI). It is marketed by GlaxoSmithKline with the brand names Zeffix, Heptovir, Epivir, and Epivir-HBV. Lamivudine has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV. It improves the seroconversion of e-antigen positive hepatitis B and also improves histology staging of the liver. (Wikipedia)