MSI_000009653

Unavailable

排名分数: -1.26
参考来源: Mus musculus (UBERON:0004645: urinary bladder urothelium)

M/z: 486.9942
Mass Window: 486.9942 ~ 486.9942 (none)

参考注释

Lamivudine-triphosphate_[M+NH4]+ (BioDeep_00000054185)
({[({[5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid

Formula: C8H14N3O12P3S (468.95110740000007)
SMILES: NC1=NC(=O)N(C=C1)C1CSC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O1

Lamivudine-triphosphate is a metabolite of lamivudine. Lamivudine (2,3-dideoxy-3-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI). It is marketed by GlaxoSmithKline with the brand names Zeffix, Heptovir, Epivir, and Epivir-HBV. Lamivudine has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV. It improves the seroconversion of e-antigen positive hepatitis B and also improves histology staging of the liver. (Wikipedia)