Aristolochic acid C

10-HYDROXY-6-NITRO-2H-PHENANTHRO[3,4-D][1,3]DIOXOLE-5-CARBOXYLIC ACID

Formula: C16H9NO7 (327.0379)
Chinese Name: 马兜铃酸 C, 马兜铃酸C
BioDeep ID: BioDeep_00000229965 ( View LC/MS Profile)
SMILES: C1OC2=C(O1)C3=C4C=C(C=CC4=CC(=C3C(=C2)C(=O)O)[N+](=O)[O-])O

Found 2 Sample Hits

m/z Adducts Species Organ Scanning Sample

m/z	Adducts	Species	Organ	Scanning	Sample
328.0512	[M+H]+ `PPM:18.4`	Posidonia oceanica	root	MALDI (CHCA)	20190613_MS1_A19r-18 - MTBLS1746 Resolution: 17μm, 246x264 Description
328.051	[M+H]+ `PPM:17.8`	Posidonia oceanica	root	MALDI (CHCA)	MS1_20180404_PO_1200 - MTBLS1746 Resolution: 17μm, 193x208 Description

328.0512

[M+H]+
PPM:18.4

Posidonia oceanica

root

MALDI (CHCA)

20190613_MS1_A19r-18 - MTBLS1746

Resolution: 17μm, 246x264

Description

328.051

[M+H]+
PPM:17.8

Posidonia oceanica

root

MALDI (CHCA)

MS1_20180404_PO_1200 - MTBLS1746

Resolution: 17μm, 193x208

Description

Aristolochic acid C is an aristolochic acid that is phenanthrene-1-carboxylic acid substituted by a methylenedioxy group at the 3,4 positions, by an hydroxy group at position 6, and by a nitro group at position 10. It has a role as a carcinogenic agent, a metabolite, a mutagen, a nephrotoxin and a toxin. It is a C-nitro compound, a member of aristolochic acids, an aromatic ether, a cyclic acetal, a monocarboxylic acid and an organic heterotetracyclic compound. Aristolochic acid C is a natural product found in Aristolochia kaempferi, Aristolochia kankauensis, and other organisms with data available. An aristolochic acid that is phenanthrene-1-carboxylic acid substituted by a methylenedioxy group at the 3,4 positions, by an hydroxy group at position 6, and by a nitro group at position 10. Annotation level-1 Aristolochic acid C is a derivative of Aristolochic acid. Aristolochic acid is a phospholipase A2 (PLA2) inhibitor, which disrupts cortical microtubule arrays and root growth in Arabidopsis[1].