Metixene

1-Methyl-3-(thioxanthen-9-ylmethyl)- piperidine hydrochloride

Formula: C20H23NS (309.1551)
Chinese Name: 1-甲基-3-(9H-噻吨-9-甲基)哌啶
BioDeep ID: BioDeep_00000033222 ( View LC/MS Profile)
SMILES: CN1CCCC(CC2C3=CC=CC=C3SC3=CC=CC=C23)C1



Found 1 Sample Hits

m/z Adducts Species Organ Scanning Sample
327.1879 [M+NH4]+
PPM:3.2
Homo sapiens NA DESI ()
160TopL,130TopR,150BottomL,140BottomR-profile - MTBLS415
Resolution: 17μm, 142x136

Description


Metixene is only found in individuals that have used or taken this drug. It is a anticholinergic used as an anti-parkinson drug. [Wikipedia]Parkinsonism is thought to result from an imbalance between the excitatory (cholinergic) and inhibitory (dopaminergic) systems in the corpus striatum. The mechanism of action of centrally active anticholinergic drugs such as metixene is considered to relate to competitive antagonism of acetylcholine at muscarinic receptors in the corpus striatum, which then restores the balance. N - Nervous system > N04 - Anti-parkinson drugs > N04A - Anticholinergic agents > N04AA - Tertiary amines C78272 - Agent Affecting Nervous System > C38149 - Antiparkinsonian Agent