Alpha-Linoleoylcholine

trimethyl({2-[(9Z,12Z)-octadeca-9,12-dienoyloxy]ethyl})azanium

Formula: C23H44NO2+ (366.3372)
Chinese Name:
BioDeep ID: BioDeep_00000032858 ( View LC/MS Profile)
SMILES: CCCCC\C=C/C\C=C/CCCCCCCC(=O)OCC[N+](C)(C)C

Found 1 Sample Hits

m/z Adducts Species Organ Scanning Sample

m/z	Adducts	Species	Organ	Scanning	Sample
367.3499	[M+H]+ `PPM:14.8`	Homo sapiens	colorectal adenocarcinoma	DESI ()	520TopL, 490TopR, 510BottomL, 500BottomR-profile - MTBLS415 Resolution: 17μm, 147x131 Description The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024).

367.3499

[M+H]+
PPM:14.8

Homo sapiens

colorectal adenocarcinoma

DESI ()

520TopL, 490TopR, 510BottomL, 500BottomR-profile - MTBLS415

Resolution: 17μm, 147x131

Description

The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024).

alpha-Linoleoylcholine is a fatty acid-choline as the ester product of alpha-Linoleoic acid and cholinel. The pharmacological effects of a series of fatty acid-choline esters have been studied on the isolated rabbit heart, the isolated guinea-pig ileum and the rat stomach. The effect changed with increasing chain length, and three different types of response were observed. The shortchain compounds produced depression of the isolated rabbit heart and spasm of the isolated guinea-pig ileum. Only one, butyrylcholine, had an erratic stimulating effect on hydrochloric acid secretion by the partially vagotomized rat stomach. Medium-chain compounds had a stimulating effect on the isolated rabbit heart, a mixed spasmogenic and relaxant effect on the isolated guinea-pig ileum, and no effect on the rat stomach. Long-chain compounds blocked the effect of acetylcholine on the isolated rabbit heart and the isolated guinea-pig ileum; they also depressed spontaneous hydrochloric acid secretion by the rat stomach. alpha-Linoleoylcholine is a fatty acid-choline as the ester product of alpha-Linoleoic acid and cholinel.