Chlorambucil

N,N-Di-2-chloroethyl-gamma-p-aminophenylbutyric acid

Formula: C14H19Cl2NO2 (303.0793)
Chinese Name: 氯氨布西
BioDeep ID: BioDeep_00000006377 ( View LC/MS Profile)
SMILES: OC(=O)CCCC1=CC=C(C=C1)N(CCCl)CCCl



Found 1 Sample Hits

m/z Adducts Species Organ Scanning Sample
304.092 [M+H]+
PPM:17.9		 Homo sapiens Liver MALDI (DHB)
20171107_FIT4_DHBpos_p70_s50 - Rappez et al (2021) SpaceM reveals metabolic states of single cells
Resolution: 50μm, 70x70

Description


A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed) L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents > L01AA - Nitrogen mustard analogues D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D009588 - Nitrogen Mustard Compounds C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D009676 - Noxae > D000477 - Alkylating Agents