L-Homocysteic acid

(2S)-2-Amino-4-sulphobutanoic acid

Formula: C4H9NO5S (183.0201)
Chinese Name: 2-氨基-4-磺基丁酸, L-同型半胱氨酸
BioDeep ID: BioDeep_00000003659 ( View LC/MS Profile)
SMILES: N[C@@H](CCS(O)(=O)=O)C(O)=O



Found 8 Sample Hits

m/z Adducts Species Organ Scanning Sample
201.0551 [M+NH4]+
PPM:5.6
Plant Root MALDI (DHB)
MPIMM_035_QE_P_PO_6pm - MPIMM_035_QE_P_PO_6pm
Resolution: 30μm, 165x170

Description

148.0085 [M+H-2H2O]+
PPM:14.9
Posidonia oceanica root MALDI (CHCA)
20190613_MS1_A19r-18 - MTBLS1746
Resolution: 17μm, 246x264

Description

148.0086 [M+H-2H2O]+
PPM:15.6
Posidonia oceanica root MALDI (CHCA)
MS1_20180404_PO_1200 - MTBLS1746
Resolution: 17μm, 193x208

Description

166.0173 [M+H-H2O]+
PPM:2.7
Homo sapiens esophagus DESI ()
LNTO22_1_4 - MTBLS385
Resolution: 17μm, 82x80

Description

183.0448 [M-H2O+NH4]+
PPM:7.6
Homo sapiens esophagus DESI ()
LNTO22_1_5 - MTBLS385
Resolution: 75μm, 135x94

Description

183.0438 [M-H2O+NH4]+
PPM:2.2
Homo sapiens esophagus DESI ()
LNTO22_1_8 - MTBLS385
Resolution: 75μm, 69x61

Description

201.0553 [M+NH4]+
PPM:6.6
Homo sapiens esophagus DESI ()
LNTO22_2_1 - MTBLS385
Resolution: 75μm, 89x88

Description

166.0164 [M+H-H2O]+
PPM:2.7
Homo sapiens esophagus DESI ()
LNTO30_7_2 - MTBLS385
Resolution: 75μm, 82x68

Description


L-homocysteic acid is a homocysteic acid with L-configuration. It has a role as a NMDA receptor agonist. It is an enantiomer of a D-homocysteic acid. L-Homocysteic acid is a sulfur-containing glutamic acid analog and a potent NMDA receptor agonist. It is related to homocysteine, a by-product of methionine metabolism. It belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom. Short-term incubation of lymphocytes with homocysteine or its oxidation product homocysteinic acid increased the formation of reactive oxygen species and cell necrosis [HMDB]