Mitraphylline

SPIRO(3H-INDOLE-3,6(4AH)-(1H)PYRANO(3,4-F)INDOLIZINE)-4-CARBOXYLIC ACID, 1,2,5,5A,7,8,10,10A-OCTAHYDRO-1-METHYL-2-OXO-, METHYL ESTER, (1S,3R,4AS,5AS,10AR)-

Formula: C21H24N2O4 (368.1736)
Chinese Name: 帽柱叶碱, 帽柱木碱, 帽柱木菲碱
BioDeep ID: BioDeep_00000000413 ( View LC/MS Profile)
SMILES: CC1C2CN3CCC4(C3CC2C(=CO1)C(=O)OC)C5=CC=CC=C5NC4=O

Found 2 Sample Hits

m/z Adducts Species Organ Scanning Sample

m/z	Adducts	Species	Organ	Scanning	Sample
369.1781	[M+H]+ `PPM:7.5`	Vitis vinifera	Fruit	MALDI (DHB)	grape_dhb_163_1 - Grape Database Resolution: 17μm, 132x115 Description Grape berries fruit, condition: Late
333.1575	[M+H-2H2O]+ `PPM:6.7`	Posidonia oceanica	root	MALDI (CHCA)	20190613_MS1_A19r-18 - MTBLS1746 Resolution: 17μm, 246x264 Description

369.1781

[M+H]+
PPM:7.5

Vitis vinifera

Fruit

MALDI (DHB)

grape_dhb_163_1 - Grape Database

Resolution: 17μm, 132x115

Description

Grape berries fruit, condition: Late

333.1575

[M+H-2H2O]+
PPM:6.7

Posidonia oceanica

root

MALDI (CHCA)

20190613_MS1_A19r-18 - MTBLS1746

Resolution: 17μm, 246x264

Description

Mitraphylline is a member of indolizines. Mitraphylline is a natural product found in Uncaria tomentosa, Mitragyna parvifolia, and other organisms with data available. See also: Cats Claw (part of); Mitragyna speciosa leaf (part of). Annotation level-1 Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils[1]. Mitraphylline is the major pentacyclic oxindolic alkaloid presented in Uncaria tomentosa. Mitraphylline inhibits lipopolysaccharide-mediated activation of primary human neutrophils[1].