M/Z: 947.6023
Hit 2 annotations: PI(20:0/20:4(6Z,8E,10E,14Z)-2OH(5S,12R))_[M+H]+; PS(22:2(13Z,16Z)/6 keto-PGF1alpha)_[M+NH4]+
- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。
Found 9 Reference Ions Near m/z 947.6023
| NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
|---|---|---|---|---|---|
| MSI_000006599 | 947.6022 | 947.602 ~ 947.6024 MzDiff: 1.5 ppm |
PI(20:0/20:4(6Z,8E,10E,14Z)-2OH(5S,12R)) (BioDeep_00000201995) Formula: C49H87O15P (946.5782) |
3.34 (100%) | Rattus norvegicus [UBERON:0004358] caput epididymis |
| MSI_000011680 Unavailable | 947.609 | 947.609 ~ 947.609 MzDiff: none |
Ditekiren (BioDeep_00000178443) Formula: C50H75N9O8 (929.5738) |
-2.02 (100%) | Mus musculus [UBERON:0012378] muscle layer of urinary bladder |
| MSI_000009035 Unreliable | 947.609 | 947.609 ~ 947.609 MzDiff: none |
Ditekiren (BioDeep_00000178443) Formula: C50H75N9O8 (929.5738) |
3.13 (100%) | Mus musculus [UBERON:0004645] urinary bladder urothelium |
| MSI_000061401 Unreliable | 947.5991 | 947.5991 ~ 947.5991 MzDiff: none |
PI(20:0/20:4(6Z,8E,10E,14Z)-2OH(5S,12R)) (BioDeep_00000201995) Formula: C49H87O15P (946.5782) |
1.04 (100%) | Mus musculus [UBERON:0000956] cerebral cortex |
| MSI_000000612 Unavailable | 947.609 | 947.609 ~ 947.609 MzDiff: none |
Ditekiren (BioDeep_00000178443) Formula: C50H75N9O8 (929.5738) |
-0.5 (100%) | Mus musculus [CL:0000066] epithelial cell |
| MSI_000058521 Unreliable | 947.6002 | 947.6002 ~ 947.6002 MzDiff: none |
PI(20:0/20:4(6Z,8E,10E,14Z)-2OH(5S,12R)) (BioDeep_00000201995) Formula: C49H87O15P (946.5782) |
1.15 (100%) | Mus musculus [UBERON:0001950] neocortex |
| MSI_000059878 Unavailable | 947.6002 | 947.6002 ~ 947.6002 MzDiff: none |
PI(20:0/20:4(6Z,8E,10E,14Z)-2OH(5S,12R)) (BioDeep_00000201995) Formula: C49H87O15P (946.5782) |
-0.67 (100%) | Mus musculus [UBERON:0002298] brainstem |
| MSI_000060777 Unavailable | 947.6002 | 947.6002 ~ 947.6002 MzDiff: none |
PI(20:0/20:4(6Z,8E,10E,14Z)-2OH(5S,12R)) (BioDeep_00000201995) Formula: C49H87O15P (946.5782) |
-0.48 (100%) | Mus musculus [UBERON:0002421] hippocampal formation |
| MSI_000062119 Unreliable | 947.5989 | 947.5989 ~ 947.5989 MzDiff: none |
PI(20:0/20:4(6Z,8E,10E,14Z)-2OH(5S,12R)) (BioDeep_00000201995) Formula: C49H87O15P (946.5782) |
0.89 (100%) | Mus musculus [UBERON:0001950] neocortex |
Found 8 Sample Hits
| Metabolite | Species | Sample | |
|---|---|---|---|
| PI(20:0/20:4(6Z,8E,10E,14Z)-2OH(5S,12R)) Formula: C49H87O15P (946.5782) Adducts: [M+H]+ (Ppm: 17.8) |
Rattus norvegicus (Epididymis) |
epik_dhb_head_ito08_44Resolution: 17μm, 299x111
|
|
| PI(20:0/20:4(6Z,8E,10E,14Z)-2OH(5S,12R)) Formula: C49H87O15P (946.5782) Adducts: [M+H]+ (Ppm: 17.4) |
Rattus norvegicus (Epididymis) |
epik_dhb_head_ito08_46Resolution: 17μm, 298x106
|
|
| PI(20:0/20:4(6Z,8E,10E,14Z)-2OH(5S,12R)) Formula: C49H87O15P (946.5782) Adducts: [M+H]+ (Ppm: 17) |
Rattus norvegicus (Epididymis) |
epik_dhb_head_ito08_47Resolution: 17μm, 301x111
|
|
| PI(20:0/20:4(6Z,8E,10E,14Z)-2OH(5S,12R)) Formula: C49H87O15P (946.5782) Adducts: [M+H]+ (Ppm: 17.8) |
Rattus norvegicus (Epididymis) |
epik_dhb_head_ito01_04Resolution: 17μm, 178x91
|
|
| PI(20:0/20:4(6Z,8E,10E,14Z)-2OH(5S,12R)) Formula: C49H87O15P (946.5782) Adducts: [M+H]+ (Ppm: 17.7) |
Rattus norvegicus (Epididymis) |
epik_dhb_head_ito01_03Resolution: 17μm, 159x110
|
|
| PI(20:0/20:4(6Z,8E,10E,14Z)-2OH(5S,12R)) Formula: C49H87O15P (946.5782) Adducts: [M+H]+ (Ppm: 17.8) |
Rattus norvegicus (normal) |
epik_dhb_head_ito01_05Resolution: 17μm, 183x105
|
|
| PI(20:0/20:4(6Z,8E,10E,14Z)-2OH(5S,12R)) Formula: C49H87O15P (946.5782) Adducts: [M+H]+ (Ppm: 17.9) |
Rattus norvegicus (Epididymis) |
epik_dhb_head_ito03_14Resolution: 17μm, 205x103
|
|
| PS(22:2(13Z,16Z)/6 keto-PGF1alpha) Formula: C48H84NO14P (929.5629) Adducts: [M+NH4]+ (Ppm: 14.6) |
Mus musculus (Lung) |
image1Resolution: 40μm, 187x165
Fig. 2 MALDI-MSI data from the same mouse lung tissue analyzed in Fig. 1. A: Optical image of the post-MSI, H&E-stained tissue section. B–D, F–G: Ion images of (B) m/z 796.6855 ([U13C-DPPC+Na]+), (C) m/z 756.5514 ([PC32:0+Na]+), (D) m/z 765.6079 ([D9-PC32:0+Na]+), (F) m/z 754.5359 ([PC32:1+Na]+), and (G) m/z 763.5923 ([D9-PC32:1+Na]+). E, H: Ratio images of (E) [D9-PC32:0+Na]+:[PC32:0+Na]+ and (H) [D9-PC32:1+Na]+:[PC32:1+Na]+. Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. U13C-DPPC, universally 13C-labeled dipalmitoyl PC; PC, phosphatidylcholine; MSI, mass spectrometry imaging; H&E, hematoxylin and eosin.
Fig 1-3, Fig S1-S3, S5 |
|
