M/Z: 917.5737
Hit 3 annotations: (1R,16Z,24E,26E,28Z)-1,18,19-trihydroxy-12-[1-(4-hydroxy-3-methoxycyclohexyl)propan-2-yl]-30-methoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone_[M+NH4]+; PE(DiMe(11,5)/6 keto-PGF1alpha)_[M+NH4]+; PC(16:0/LTE4)_[M+H]+
- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。
Found 3 Reference Ions Near m/z 917.5737
| NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
|---|---|---|---|---|---|
| MSI_000003887 Unreliable | 917.5738 | 917.5738 ~ 917.5738 MzDiff: none |
(1R,16Z,24E,26E,28Z)-1,18,19-trihydroxy-12-[1-(4-hydroxy-3-methoxycyclohexyl)propan-2-yl]-30-methoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone (BioDeep_00000025499) Formula: C50H77NO13 (899.5395) |
1.4 (100%) | Homo sapiens [UBERON:0002107] liver |
| MSI_000050039 Unreliable | 917.5728 | 917.5728 ~ 917.5728 MzDiff: none |
PC(16:0/LTE4) (BioDeep_00000210925) Formula: C47H85N2O11PS (916.5611) |
1.09 (100%) | Mytilus edulis [UBERON:0009120] gill filament |
| MSI_000050950 Unreliable | 917.5728 | 917.5728 ~ 917.5728 MzDiff: none |
PC(16:0/LTE4) (BioDeep_00000210925) Formula: C47H85N2O11PS (916.5611) |
0.52 (100%) | Mytilus edulis [UBERON:2001856] gill ray |
Found 6 Sample Hits
| Metabolite | Species | Sample | |
|---|---|---|---|
| (1R,16Z,24E,26E,28Z)-1,18,19-trihydroxy-12-[1-(4-hydroxy-3-methoxycyclohexyl)propan-2-yl]-30-methoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone Formula: C50H77NO13 (899.5395) Adducts: [M+NH4]+ (Ppm: 0.6) |
Homo sapiens (Liver) |
20171107_FIT4_DHBpos_p70_s50Resolution: 50μm, 70x70
|
|
| PE(DiMe(11,5)/6 keto-PGF1alpha) Formula: C47H82NO13P (899.5523) Adducts: [M+NH4]+ (Ppm: 11.1) |
Mus musculus (Lung) |
image1Resolution: 40μm, 187x165
Fig. 2 MALDI-MSI data from the same mouse lung tissue analyzed in Fig. 1. A: Optical image of the post-MSI, H&E-stained tissue section. B–D, F–G: Ion images of (B) m/z 796.6855 ([U13C-DPPC+Na]+), (C) m/z 756.5514 ([PC32:0+Na]+), (D) m/z 765.6079 ([D9-PC32:0+Na]+), (F) m/z 754.5359 ([PC32:1+Na]+), and (G) m/z 763.5923 ([D9-PC32:1+Na]+). E, H: Ratio images of (E) [D9-PC32:0+Na]+:[PC32:0+Na]+ and (H) [D9-PC32:1+Na]+:[PC32:1+Na]+. Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. U13C-DPPC, universally 13C-labeled dipalmitoyl PC; PC, phosphatidylcholine; MSI, mass spectrometry imaging; H&E, hematoxylin and eosin.
Fig 1-3, Fig S1-S3, S5 |
|
| PC(16:0/LTE4) Formula: C47H85N2O11PS (916.5611) Adducts: [M+H]+ (Ppm: 9.5) |
Homo sapiens (colorectal adenocarcinoma) |
80TopL, 50TopR, 70BottomL, 60BottomR-profileResolution: 17μm, 137x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| (1R,16Z,24E,26E,28Z)-1,18,19-trihydroxy-12-[1-(4-hydroxy-3-methoxycyclohexyl)propan-2-yl]-30-methoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone Formula: C50H77NO13 (899.5395) Adducts: [M+NH4]+ (Ppm: 0.4) |
Mytilus edulis (mantle) |
20190201_MS38_Crassostrea_Mantle_350-1500_DHB_pos_A28_10um_270x210Resolution: 10μm, 270x210
|
|
| PC(16:0/LTE4) Formula: C47H85N2O11PS (916.5611) Adducts: [M+H]+ (Ppm: 4.8) |
Mytilus edulis (gill) |
20190202_MS38_Crassostrea_Gill_350-1500_DHB_pos_A25_11um_305x210Resolution: 11μm, 305x210
single cell layer |
|
| PC(16:0/LTE4) Formula: C47H85N2O11PS (916.5611) Adducts: [M+H]+ (Ppm: 5.8) |
Mytilus edulis (mantle) |
20190216_MS38_Mytilus_mantle_350-1500_DHB_pos_A26_10um_275x210Resolution: 10μm, 275x210
|
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