- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。
Found 14 Reference Ions Near m/z 834.5137
| NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
|---|---|---|---|---|---|
| MSI_000065376 Reliable | 834.5193 | 834.519 ~ 834.5199 MzDiff: 3.6 ppm |
PE(22:5(4Z,7Z,10Z,13Z,16Z)/22:6(5Z,8E,10Z,13Z,15E,19Z)-2OH(7S, 17S)) (BioDeep_00000209194) Formula: C49H76NO10P (869.5207) |
3.51 (67%) | Homo sapiens [UBERON:0001155] colon |
| MSI_000057887 Unreliable | 834.5195 | 834.5191 ~ 834.5198 MzDiff: 2.8 ppm |
PE(22:5(4Z,7Z,10Z,13Z,16Z)/22:6(5Z,8E,10Z,13Z,15E,19Z)-2OH(7S, 17S)) (BioDeep_00000209194) Formula: C49H76NO10P (869.5207) |
4.8 (40%) | Homo sapiens [UBERON:0001043] esophagus |
| MSI_000052619 Unreliable | 834.5055 | 834.5055 ~ 834.5055 MzDiff: none |
Not Annotated | 1.14 (%) | Homo sapiens [UBERON:0001052] rectum |
| MSI_000047410 Unreliable | 834.5078 | 834.5078 ~ 834.5078 MzDiff: none |
Not Annotated | 2.31 (%) | Homo sapiens [UBERON:0013067] colorectal mucosa |
| MSI_000051819 Unreliable | 834.5137 | 834.5137 ~ 834.5137 MzDiff: none |
alpha-Chaconine (BioDeep_00000003994) Formula: C45H73NO14 (851.5031) |
2.43 (100%) | Homo sapiens [UBERON:0001052] rectum |
| MSI_000047180 Unreliable | 834.5159 | 834.5159 ~ 834.5159 MzDiff: none |
alpha-Chaconine (BioDeep_00000003994) Formula: C45H73NO14 (851.5031) |
2.62 (100%) | Homo sapiens [UBERON:0013067] colorectal mucosa |
| MSI_000051858 Unreliable | 834.5215 | 834.5215 ~ 834.5215 MzDiff: none |
PS(16:0/PGF2alpha) (BioDeep_00000206136) Formula: C42H76NO13P (833.5054) |
2.41 (100%) | Homo sapiens [UBERON:0001052] rectum |
| MSI_000026296 Unreliable | 834.5217 | 834.5217 ~ 834.5217 MzDiff: 0.0 ppm |
PS(18:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) (BioDeep_00000019322) Formula: C46H76NO10P (833.5207) |
3.54 (100%) | Mus musculus [UBERON:0002048] lung |
| MSI_000043810 Unreliable | 834.5223 | 834.5223 ~ 834.5223 MzDiff: none |
PS(16:0/PGF2alpha) (BioDeep_00000206136) Formula: C42H76NO13P (833.5054) |
1.28 (100%) | Homo sapiens [UBERON:0001043] esophagus |
| MSI_000065802 Unreliable | 834.5181 | 834.5181 ~ 834.5181 MzDiff: none |
PS(16:0/PGF2alpha) (BioDeep_00000206136) Formula: C42H76NO13P (833.5054) |
1.15 (100%) | Homo sapiens [UBERON:0001155] colon |
| MSI_000002899 Unavailable | 834.5182 | 834.5182 ~ 834.5182 MzDiff: none |
SM(d17:2(4E,8Z)/LTE4) (BioDeep_00000215412) Formula: C45H80N3O9PS (869.5353) |
-0.54 (100%) | Rattus norvegicus [UBERON:0001950] neocortex |
| MSI_000003602 Unavailable | 834.5182 | 834.5182 ~ 834.5182 MzDiff: none |
SM(d17:2(4E,8Z)/LTE4) (BioDeep_00000215412) Formula: C45H80N3O9PS (869.5353) |
-0.68 (100%) | Rattus norvegicus [UBERON:0002037] cerebellum |
| MSI_000004913 Unreliable | 834.5182 | 834.5182 ~ 834.5182 MzDiff: none |
SM(d17:2(4E,8Z)/LTE4) (BioDeep_00000215412) Formula: C45H80N3O9PS (869.5353) |
0.38 (100%) | Rattus norvegicus [UBERON:0002298] brainstem |
| MSI_000005456 Unreliable | 834.5182 | 834.5182 ~ 834.5182 MzDiff: none |
SM(d17:2(4E,8Z)/LTE4) (BioDeep_00000215412) Formula: C45H80N3O9PS (869.5353) |
2.33 (100%) | Rattus norvegicus [UBERON:0002435] striatum |
Found 12 Sample Hits
| Metabolite | Species | Sample | |
|---|---|---|---|
| SM(d17:2(4E,8Z)/LTE4) Formula: C45H80N3O9PS (869.5353) Adducts: [M+H-2H2O]+ (Ppm: 3.8) |
Rattus norvegicus (Brain) |
Spectroswiss - sol_2x_br_2Resolution: 17μm, 488x193
|
|
| PS(18:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) Formula: C46H76NO10P (833.5207) Adducts: [M+H]+ (Ppm: 8.9) |
Mus musculus (Lung) |
image2Resolution: 40μm, 550x256
Supplementary Figure S6. Ion distribution images for (a) [PC36:4+Na]+ (m/z 804.5514) and (b)
[PC38:6+Na]+ (m/z 828.5515) obtained from mouse lung tissue collected 6 h after administration of D9-
choline and U13C-DPPC–containing CHF5633. Parts-per-million (ppm) mass errors are indicated in
parentheses. (c) Magnification of the boxed region in (a) with selected bronchiolar regions outlined in
white boxes. (d) The corresponding H&E-stained tissue section with the same selected bronchiolar
regions outlined in black boxes. These data demonstrate the co-localisation of the polyunsaturated lipids
PC36:4 and PC38:6 with the bronchiolar regions of the lung. All MSI images were visualised using
total ion current normalisation and hotspot removal (high quantile = 99%). |
|
| alpha-Chaconine Formula: C45H73NO14 (851.5031) Adducts: [M+H-H2O]+ (Ppm: 18.9) |
Homo sapiens (esophagus) |
LNTO22_1_4Resolution: 17μm, 82x80
|
|
| PS(16:0/PGF2alpha) Formula: C42H76NO13P (833.5054) Adducts: [M+H]+ (Ppm: 11.5) |
Homo sapiens (esophagus) |
LNTO22_1_9Resolution: 75μm, 89x74
|
|
| alpha-Chaconine Formula: C45H73NO14 (851.5031) Adducts: [M+H-H2O]+ (Ppm: 19.3) |
Homo sapiens (colorectal adenocarcinoma) |
80TopL, 50TopR, 70BottomL, 60BottomR-profileResolution: 17μm, 137x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| alpha-Chaconine Formula: C45H73NO14 (851.5031) Adducts: [M+H-H2O]+ (Ppm: 18.3) |
Homo sapiens (colorectal adenocarcinoma) |
520TopL, 490TopR, 510BottomL, 500BottomR-profileResolution: 17μm, 147x131
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| alpha-Chaconine Formula: C45H73NO14 (851.5031) Adducts: [M+H-H2O]+ (Ppm: 16.7) |
Homo sapiens (colorectal adenocarcinoma) |
439TopL, 409TopR, 429BottomL, 419BottomR-profileResolution: 17μm, 157x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| alpha-Chaconine Formula: C45H73NO14 (851.5031) Adducts: [M+H-H2O]+ (Ppm: 16.2) |
Homo sapiens (NA) |
160TopL,130TopR,150BottomL,140BottomR-profileResolution: 17μm, 142x136
|
|
| PS(18:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) Formula: C46H76NO10P (833.5207) Adducts: [M+H]+ (Ppm: 7.1) |
Homo sapiens (esophagus) |
TO31TResolution: 75μm, 56x54
|
|
| PS(16:0/PGF2alpha) Formula: C42H76NO13P (833.5054) Adducts: [M+H]+ (Ppm: 6.5) |
Homo sapiens (colorectal adenocarcinoma) |
240TopL, 210TopR, 230BottomL, 220BottomR-centroidResolution: 50μm, 142x141
|
|
| PE(22:5(4Z,7Z,10Z,13Z,16Z)/22:6(5Z,8E,10Z,13Z,15E,19Z)-2OH(7S, 17S)) Formula: C49H76NO10P (869.5207) Adducts: [M+H-2H2O]+ (Ppm: 15.7) |
Homo sapiens (colorectal adenocarcinoma) |
200TopL, 170TopR, 190BottomL, 180BottomR-centroidResolution: 50μm, 132x126
|
|
| PE(22:5(4Z,7Z,10Z,13Z,16Z)/22:6(5Z,8E,10Z,13Z,15E,19Z)-2OH(7S, 17S)) Formula: C49H76NO10P (869.5207) Adducts: [M+H-2H2O]+ (Ppm: 14.6) |
Homo sapiens (colorectal adenocarcinoma) |
160TopL,130TopR,150BottomL,140BottomR-centroidResolution: 50μm, 142x136
|
|
