- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。
Found 12 Reference Ions Near m/z 810.4565
| NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
|---|---|---|---|---|---|
| MSI_000063134 Reliable | 810.4533 | 810.4531 ~ 810.4534 MzDiff: 1.0 ppm |
Josamycin (BioDeep_00000002552) Formula: C42H69NO15 (827.4667) |
2.02 (100%) | Mus musculus [UBERON:0000956] cerebral cortex |
| MSI_000058693 Unreliable | 810.4532 | 810.4532 ~ 810.4532 MzDiff: 0.0 ppm |
Pimecrolimus (BioDeep_00000018191) Formula: C43H68ClNO11 (809.4481) |
2.74 (50%) | Mus musculus [UBERON:0001950] neocortex |
| MSI_000061117 Unreliable | 810.4556 | 810.4556 ~ 810.4556 MzDiff: none |
Josamycin (BioDeep_00000002552) Formula: C42H69NO15 (827.4667) |
1.7 (100%) | Mus musculus [UBERON:0000956] cerebral cortex |
| MSI_000002406 Unreliable | 810.4529 | 810.4529 ~ 810.4529 MzDiff: none |
Josamycin (BioDeep_00000002552) Formula: C42H69NO15 (827.4667) |
1.71 (100%) | Rattus norvegicus [UBERON:0001950] neocortex |
| MSI_000003172 Unreliable | 810.4529 | 810.4529 ~ 810.4529 MzDiff: none |
Josamycin (BioDeep_00000002552) Formula: C42H69NO15 (827.4667) |
1.47 (100%) | Rattus norvegicus [UBERON:0002037] cerebellum |
| MSI_000004286 Unreliable | 810.4552 | 810.4552 ~ 810.4552 MzDiff: none |
Josamycin (BioDeep_00000002552) Formula: C42H69NO15 (827.4667) |
0.8 (100%) | Homo sapiens [UBERON:0002107] liver |
| MSI_000005214 Unavailable | 810.4529 | 810.4529 ~ 810.4529 MzDiff: none |
Josamycin (BioDeep_00000002552) Formula: C42H69NO15 (827.4667) |
-0.73 (100%) | Rattus norvegicus [UBERON:0002298] brainstem |
| MSI_000005850 Unavailable | 810.4529 | 810.4529 ~ 810.4529 MzDiff: none |
Josamycin (BioDeep_00000002552) Formula: C42H69NO15 (827.4667) |
-0.74 (100%) | Rattus norvegicus [UBERON:0002435] striatum |
| MSI_000027760 Unreliable | 810.466 | 810.466 ~ 810.466 MzDiff: none |
Not Annotated | 2.04 (0%) | Mus musculus [UBERON:0002048] lung |
| MSI_000060066 Unavailable | 810.4532 | 810.4532 ~ 810.4532 MzDiff: none |
Pimecrolimus (BioDeep_00000018191) Formula: C43H68ClNO11 (809.4481) |
-0.89 (100%) | Mus musculus [UBERON:0002298] brainstem |
| MSI_000060475 Unavailable | 810.4532 | 810.4532 ~ 810.4532 MzDiff: none |
Pimecrolimus (BioDeep_00000018191) Formula: C43H68ClNO11 (809.4481) |
-0.18 (100%) | Mus musculus [UBERON:0002421] hippocampal formation |
| MSI_000062250 Unavailable | 810.4563 | 810.4563 ~ 810.4563 MzDiff: none |
Pimecrolimus (BioDeep_00000018191) Formula: C43H68ClNO11 (809.4481) |
-0.19 (100%) | Mus musculus [UBERON:0001950] neocortex |
Found 6 Sample Hits
| Metabolite | Species | Sample | |
|---|---|---|---|
| Josamycin Formula: C42H69NO15 (827.4667) Adducts: [M+H-H2O]+ (Ppm: 13) |
Rattus norvegicus (Brain) |
Spectroswiss - sol_2x_br_2Resolution: 17μm, 488x193
|
|
| Josamycin Formula: C42H69NO15 (827.4667) Adducts: [M+H-H2O]+ (Ppm: 10.1) |
Homo sapiens (Liver) |
20171107_FIT4_DHBpos_p70_s50Resolution: 50μm, 70x70
|
|
| Goldinodox Formula: C44H62N2O12 (810.4303) Adducts: [M-H2O+NH4]+ (Ppm: 3.7) |
Mus musculus (Lung) |
image1Resolution: 40μm, 187x165
Fig. 2 MALDI-MSI data from the same mouse lung tissue analyzed in Fig. 1. A: Optical image of the post-MSI, H&E-stained tissue section. B–D, F–G: Ion images of (B) m/z 796.6855 ([U13C-DPPC+Na]+), (C) m/z 756.5514 ([PC32:0+Na]+), (D) m/z 765.6079 ([D9-PC32:0+Na]+), (F) m/z 754.5359 ([PC32:1+Na]+), and (G) m/z 763.5923 ([D9-PC32:1+Na]+). E, H: Ratio images of (E) [D9-PC32:0+Na]+:[PC32:0+Na]+ and (H) [D9-PC32:1+Na]+:[PC32:1+Na]+. Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. U13C-DPPC, universally 13C-labeled dipalmitoyl PC; PC, phosphatidylcholine; MSI, mass spectrometry imaging; H&E, hematoxylin and eosin.
Fig 1-3, Fig S1-S3, S5 |
|
| Pimecrolimus Formula: C43H68ClNO11 (809.4481) Adducts: [M+H]+ (Ppm: 1.2) |
Mus musculus (brain) |
Brain01_Bregma1-42_02_centroidResolution: 17μm, 434x258
|
|
| Josamycin Formula: C42H69NO15 (827.4667) Adducts: [M+H-H2O]+ (Ppm: 9.6) |
Mus musculus (brain) |
Brain01_Bregma1-42_01_centroidResolution: 17μm, 447x118
|
|
| Josamycin Formula: C42H69NO15 (827.4667) Adducts: [M+H-H2O]+ (Ppm: 12.7) |
Mus musculus (brain) |
Brain02_Bregma-3-88Resolution: 17μm, 288x282
|
|
