- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。
Found 7 Reference Ions Near m/z 789.5696
| NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
|---|---|---|---|---|---|
| MSI_000047072 Unreliable | 789.5623 | 789.5623 ~ 789.5623 MzDiff: none |
SM(d17:1/PGF1alpha) (BioDeep_00000215391) Formula: C42H81N2O9P (788.5679) |
2.87 (100%) | Homo sapiens [UBERON:0013067] colorectal mucosa |
| MSI_000047544 Unreliable | 789.5696 | 789.5696 ~ 789.5696 MzDiff: none |
PS(18:0/18:1(9Z)) (BioDeep_00000019314) Formula: C42H80NO10P (789.552) |
2.24 (100%) | Homo sapiens [UBERON:0013067] colorectal mucosa |
| MSI_000052302 Unreliable | 789.5617 | 789.5617 ~ 789.5617 MzDiff: none |
SM(d17:1/PGF1alpha) (BioDeep_00000215391) Formula: C42H81N2O9P (788.5679) |
2.21 (100%) | Homo sapiens [UBERON:0001052] rectum |
| MSI_000052516 Unreliable | 789.5691 | 789.5691 ~ 789.5691 MzDiff: none |
Not Annotated | 1.85 (0%) | Homo sapiens [UBERON:0001052] rectum |
| MSI_000053099 Unreliable | 789.5793 | 789.5793 ~ 789.5793 MzDiff: none |
PC(20:5(5Z,8Z,11Z,14Z,17Z)/P-18:1(11Z)) (BioDeep_00000029780) Formula: C46H80NO7P (789.5672) |
2.96 (100%) | DESI [NOVOCELL:BACKGROUND] blank |
| MSI_000026449 Unreliable | 789.561 | 789.561 ~ 789.561 MzDiff: none |
PA(22:1(13Z)/18:1(12Z)-2OH(9,10)) (BioDeep_00000190704) Formula: C43H81O10P (788.5567) |
1.79 (100%) | Mus musculus [UBERON:0002048] lung |
| MSI_000026674 Unreliable | 789.5647 | 789.5647 ~ 789.5647 MzDiff: none |
PS(18:0/18:1(9Z)) (BioDeep_00000019314) Formula: C42H80NO10P (789.552) |
1.79 (100%) | Mus musculus [UBERON:0002048] lung |
Found 6 Sample Hits
| Metabolite | Species | Sample | |
|---|---|---|---|
| PS(18:0/18:1(9Z)) Formula: C42H80NO10P (789.552) Adducts: [M-H2O+NH4]+ (Ppm: 14.7) |
Mus musculus (Lung) |
image1Resolution: 40μm, 187x165
Fig. 2 MALDI-MSI data from the same mouse lung tissue analyzed in Fig. 1. A: Optical image of the post-MSI, H&E-stained tissue section. B–D, F–G: Ion images of (B) m/z 796.6855 ([U13C-DPPC+Na]+), (C) m/z 756.5514 ([PC32:0+Na]+), (D) m/z 765.6079 ([D9-PC32:0+Na]+), (F) m/z 754.5359 ([PC32:1+Na]+), and (G) m/z 763.5923 ([D9-PC32:1+Na]+). E, H: Ratio images of (E) [D9-PC32:0+Na]+:[PC32:0+Na]+ and (H) [D9-PC32:1+Na]+:[PC32:1+Na]+. Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. U13C-DPPC, universally 13C-labeled dipalmitoyl PC; PC, phosphatidylcholine; MSI, mass spectrometry imaging; H&E, hematoxylin and eosin.
Fig 1-3, Fig S1-S3, S5 |
|
| PS(18:0/18:1(9Z)) Formula: C42H80NO10P (789.552) Adducts: [M-H2O+NH4]+ (Ppm: 14.5) |
Mus musculus (Lung) |
image3Resolution: 40μm, 146x190
Fig. 4 MALDI-MSI data of mouse lung tissue after administration with D9-choline and U13C-DPPC–containing Poractant alfa surfactant (labels administered 12 h prior to tissue collection). Ion images of (A) m/z 796.6856 ([U13C-DPPC+Na]+), (B) m/z 756.5154 [PC32:0+Na]+), and (C) m/z 765.6079 ([D9-PC32:0+Na]+). D: Overlay image of [U13C-PC32:0+Na]+ (red) and [D9-PC32:0+Na]+ (green). Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. MSI, mass spectrometry imaging; PC, phosphatidylcholine; U13C-DPPC, universally 13C-labeled dipalmitoyl PC. |
|
| PS(18:0/18:1(9Z)) Formula: C42H80NO10P (789.552) Adducts: [M-H2O+NH4]+ (Ppm: 13.3) |
Mus musculus (Lung) |
image5Resolution: 40μm, 163x183
Supplementary Figure S8. MALDI-MSI data of mouse lung tissue administered with D9-choline and
U 13C-DPPC–containing Poractant alfa surfactant (labels administered 18 h prior to sacrifice). Ion
images of (a) m/z 796.6856 ([U13C-DPPC+Na]+), (b) m/z 756.5154 [PC32:0+Na]+ and (c) m/z 765.6079
([D9-PC32:0+Na]+). (d) Overlay image of [U13C-DPPC+Na]+ (red) and [D9-PC32:0+Na]+ (green).
Parts per million (ppm) mass errors are indicated in parentheses. All images were visualised using totalion-current normalisation and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. |
|
| PS(18:0/18:1(9Z)) Formula: C42H80NO10P (789.552) Adducts: [M-H2O+NH4]+ (Ppm: 7.1) |
Homo sapiens (colorectal adenocarcinoma) |
80TopL, 50TopR, 70BottomL, 60BottomR-profileResolution: 17μm, 137x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| m/z_789.5698 Formula: - (n/a) Adducts: (Ppm: 0) |
Homo sapiens (colorectal adenocarcinoma) |
520TopL, 490TopR, 510BottomL, 500BottomR-profileResolution: 17μm, 147x131
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| m/z_789.5691 Formula: - (n/a) Adducts: (Ppm: 0) |
Homo sapiens (colorectal adenocarcinoma) |
439TopL, 409TopR, 429BottomL, 419BottomR-profileResolution: 17μm, 157x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
