M/Z: 775.6139
Hit 3 annotations: PC(16:0/18:2)_[M+NH4]+; PA(19:0/22:0)_[M+H]+; PG(a-13:0/i-20:0)_[M+K]+
- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。
Found 24 Reference Ions Near m/z 775.6139
| NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
|---|---|---|---|---|---|
| MSI_000006996 Reliable | 775.6054 | 775.6052 ~ 775.6057 MzDiff: 2.1 ppm |
SM(d19:1/18:1(12Z)-2OH(9,10)) (BioDeep_00000215682) Formula: C42H83N2O8P (774.5887) |
13.85 (100%) | Rattus norvegicus [UBERON:0004359] corpus epididymis |
| MSI_000063185 Reliable | 775.6043 | 775.6042 ~ 775.6045 MzDiff: 1.3 ppm |
PC(18:2(9Z,12Z)/16:0) (BioDeep_00000029408) Formula: C42H80NO8P (757.5621) |
2.88 (50%) | Mus musculus [UBERON:0000956] cerebral cortex |
| MSI_000020741 Reliable | 775.6054 | 775.6052 ~ 775.6057 MzDiff: 2.1 ppm |
SM(d19:1/18:1(12Z)-2OH(9,10)) (BioDeep_00000215682) Formula: C42H83N2O8P (774.5887) |
5.9 (100%) | Rattus norvegicus [UBERON:0004360] cauda epididymis |
| MSI_000061415 Unreliable | 775.6057 | 775.6056 ~ 775.6059 MzDiff: 1.4 ppm |
SM(d19:1/18:1(12Z)-2OH(9,10)) (BioDeep_00000215682) Formula: C42H83N2O8P (774.5887) |
1.68 (100%) | Mus musculus [UBERON:0000956] cerebral cortex |
| MSI_000058543 Unreliable | 775.6044 | 775.6043 ~ 775.6046 MzDiff: 1.5 ppm |
SM(d19:1/18:1(12Z)-2OH(9,10)) (BioDeep_00000215682) Formula: C42H83N2O8P (774.5887) |
0.19 (100%) | Mus musculus [UBERON:0001950] neocortex |
| MSI_000022070 Unreliable | 775.6057 | 775.6057 ~ 775.6057 MzDiff: none |
PA(19:0/i-22:0) (BioDeep_00000107983) Formula: C44H87O8P (774.6138) |
0.47 (100%) | Mus musculus [UBERON:0001499] muscle of arm |
| MSI_000044066 Unreliable | 775.6041 | 775.6041 ~ 775.6041 MzDiff: none |
SM(d19:1/18:1(12Z)-2OH(9,10)) (BioDeep_00000215682) Formula: C42H83N2O8P (774.5887) |
1.63 (100%) | Rattus norvegicus [UBERON:0002264] olfactory bulb |
| MSI_000002507 Unreliable | 775.6042 | 775.6042 ~ 775.6042 MzDiff: none |
PC(16:0/18:2) (BioDeep_00001898006) Formula: C42H80NO8P (757.5621) |
0.78 (100%) | Rattus norvegicus [UBERON:0001950] neocortex |
| MSI_000003085 Unreliable | 775.6042 | 775.6042 ~ 775.6042 MzDiff: none |
PC(16:0/18:2) (BioDeep_00001898006) Formula: C42H80NO8P (757.5621) |
2.19 (100%) | Rattus norvegicus [UBERON:0002037] cerebellum |
| MSI_000005048 Unavailable | 775.6042 | 775.6042 ~ 775.6042 MzDiff: none |
PC(16:0/18:2) (BioDeep_00001898006) Formula: C42H80NO8P (757.5621) |
-0.44 (100%) | Rattus norvegicus [UBERON:0002298] brainstem |
| MSI_000005788 Unavailable | 775.6042 | 775.6042 ~ 775.6042 MzDiff: none |
PC(16:0/18:2) (BioDeep_00001898006) Formula: C42H80NO8P (757.5621) |
-0.65 (100%) | Rattus norvegicus [UBERON:0002435] striatum |
| MSI_000004669 Unreliable | 775.6044 | 775.6044 ~ 775.6044 MzDiff: none |
SM(d19:1/18:1(12Z)-2OH(9,10)) (BioDeep_00000215682) Formula: C42H83N2O8P (774.5887) |
0.33 (100%) | Homo sapiens [UBERON:0002107] liver |
| MSI_000059906 Unavailable | 775.6046 | 775.6046 ~ 775.6046 MzDiff: none |
SM(d19:1/18:1(12Z)-2OH(9,10)) (BioDeep_00000215682) Formula: C42H83N2O8P (774.5887) |
-0.69 (100%) | Mus musculus [UBERON:0002298] brainstem |
| MSI_000060734 Unavailable | 775.6046 | 775.6046 ~ 775.6046 MzDiff: none |
SM(d19:1/18:1(12Z)-2OH(9,10)) (BioDeep_00000215682) Formula: C42H83N2O8P (774.5887) |
-0.46 (100%) | Mus musculus [UBERON:0002421] hippocampal formation |
| MSI_000023078 Unreliable | 775.6057 | 775.6057 ~ 775.6057 MzDiff: none |
PA(19:0/i-22:0) (BioDeep_00000107983) Formula: C44H87O8P (774.6138) |
0.62 (100%) | Mus musculus [UBERON:0004250] upper arm bone |
| MSI_000062084 Unreliable | 775.6059 | 775.6059 ~ 775.6059 MzDiff: none |
SM(d19:1/18:1(12Z)-2OH(9,10)) (BioDeep_00000215682) Formula: C42H83N2O8P (774.5887) |
1.32 (100%) | Mus musculus [UBERON:0001950] neocortex |
| MSI_000027070 Unreliable | 775.6059 | 775.6059 ~ 775.6059 MzDiff: none |
PA(19:0/22:0) (BioDeep_00000107413) Formula: C44H87O8P (774.6138) |
1.77 (100%) | Mus musculus [UBERON:0002048] lung |
| MSI_000028250 Unreliable | 775.6065 | 775.6065 ~ 775.6065 MzDiff: none |
PA(19:0/i-22:0) (BioDeep_00000107983) Formula: C44H87O8P (774.6138) |
1.61 (100%) | Macropus giganteus [UBERON:0001891] midbrain |
| MSI_000029594 Unreliable | 775.6065 | 775.6065 ~ 775.6065 MzDiff: none |
PA(19:0/i-22:0) (BioDeep_00000107983) Formula: C44H87O8P (774.6138) |
0.25 (100%) | Macropus giganteus [UBERON:0002336] corpus callosum |
| MSI_000026818 Unreliable | 775.6069 | 775.6069 ~ 775.6069 MzDiff: none |
SM(d19:1/18:1(12Z)-2OH(9,10)) (BioDeep_00000215682) Formula: C42H83N2O8P (774.5887) |
1.79 (100%) | Mus musculus [UBERON:0002048] lung |
| MSI_000028295 Unreliable | 775.6139 | 775.6139 ~ 775.6139 MzDiff: none |
PG(a-13:0/i-20:0) (BioDeep_00000109000) Formula: C39H77O10P (736.5254) |
1.47 (100%) | Macropus giganteus [UBERON:0001891] midbrain |
| MSI_000061604 Unavailable | 775.6181 | 775.6181 ~ 775.6181 MzDiff: none |
Not Annotated | -0.35 (0%) | Mus musculus [UBERON:0000956] cerebral cortex |
| MSI_000062353 Unavailable | 775.6181 | 775.6181 ~ 775.6181 MzDiff: none |
Not Annotated | -0.35 (0%) | Mus musculus [UBERON:0001950] neocortex |
| MSI_000062786 Unavailable | 775.6181 | 775.6181 ~ 775.6181 MzDiff: none |
Not Annotated | -0.35 (0%) | Mus musculus [UBERON:0002421] hippocampal formation |
Found 8 Sample Hits
| Metabolite | Species | Sample | |
|---|---|---|---|
| PC(16:0/18:2) Formula: C42H80NO8P (757.5621) Adducts: [M+NH4]+ (Ppm: 10.6) |
Rattus norvegicus (Brain) |
Spectroswiss - sol_2x_br_2Resolution: 17μm, 488x193
|
|
| PA(19:0/22:0) Formula: C44H87O8P (774.6138) Adducts: [M+H]+ (Ppm: 16.1) |
Mus musculus (Lung) |
image1Resolution: 40μm, 187x165
Fig. 2 MALDI-MSI data from the same mouse lung tissue analyzed in Fig. 1. A: Optical image of the post-MSI, H&E-stained tissue section. B–D, F–G: Ion images of (B) m/z 796.6855 ([U13C-DPPC+Na]+), (C) m/z 756.5514 ([PC32:0+Na]+), (D) m/z 765.6079 ([D9-PC32:0+Na]+), (F) m/z 754.5359 ([PC32:1+Na]+), and (G) m/z 763.5923 ([D9-PC32:1+Na]+). E, H: Ratio images of (E) [D9-PC32:0+Na]+:[PC32:0+Na]+ and (H) [D9-PC32:1+Na]+:[PC32:1+Na]+. Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. U13C-DPPC, universally 13C-labeled dipalmitoyl PC; PC, phosphatidylcholine; MSI, mass spectrometry imaging; H&E, hematoxylin and eosin.
Fig 1-3, Fig S1-S3, S5 |
|
| PG(a-13:0/i-20:0) Formula: C39H77O10P (736.5254) Adducts: [M+K]+ (Ppm: 11.9) |
Macropus giganteus (Brain) |
170321_kangaroobrain-dan3-pos_maxof50.0_med1Resolution: 50μm, 81x50
Sample information
Organism: Macropus giganteus (kangaroo)
Organism part: Brain
Condition: Wildtype
Sample growth conditions: Wild |
|
| PA(19:0/22:0) Formula: C44H87O8P (774.6138) Adducts: [M+H]+ (Ppm: 13.4) |
Homo sapiens (esophagus) |
LNTO22_1_3Resolution: 75μm, 121x68
|
|
| PA(19:0/22:0) Formula: C44H87O8P (774.6138) Adducts: [M+H]+ (Ppm: 14.3) |
Homo sapiens (esophagus) |
LNTO29_16_2Resolution: 17μm, 95x101
|
|
| PA(19:0/22:0) Formula: C44H87O8P (774.6138) Adducts: [M+H]+ (Ppm: 12.2) |
Homo sapiens (esophagus) |
LNTO22_1_9Resolution: 75μm, 89x74
|
|
| PA(19:0/22:0) Formula: C44H87O8P (774.6138) Adducts: [M+H]+ (Ppm: 14.7) |
Homo sapiens (esophagus) |
LNTO29_16_3Resolution: 17μm, 108x107
|
|
| PA(19:0/22:0) Formula: C44H87O8P (774.6138) Adducts: [M+H]+ (Ppm: 13.4) |
Homo sapiens (esophagus) |
LNTO22_1_8Resolution: 75μm, 69x61
|
|
