M/Z: 763.453


Hit 1 annotations:  PG(i-12:0/PGE2)_[M+H]+


在BioDeep NovoCell知识数据库中,参考离子总共被划分为4个级别。
  • Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
  • Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
  • Unreliable: 这个参考离子具有较高的排名价值,但缺乏可重复性。
  • Unavailable: 由于排名价值低且缺乏可重复性,这个参考离子不应用于注释。

Found 5 Reference Ions Near m/z 763.453
NovoCell ID m/z Mass Window Metabolite Ranking Anatomy Context
MSI_000029446 Unreliable 763.453 763.453 ~ 763.453
MzDiff: none
PG(i-12:0/PGE2) (BioDeep_00000196069)
Formula: C38H67O13P (762.4319)
0.87 (100%) Macropus giganteus
[UBERON:0002336] corpus callosum
MSI_000031779 Unavailable 763.453 763.453 ~ 763.453
MzDiff: none
PG(i-12:0/PGE2) (BioDeep_00000196069)
Formula: C38H67O13P (762.4319)
-0.14 (100%) Macropus giganteus
[UBERON:0006093] precuneus cortex
MSI_000022469 Unreliable 763.4611 763.4611 ~ 763.4611
MzDiff: none
PA(17:0/PGJ2) (BioDeep_00000188501)
Formula: C40H69O10P (740.4628)
1.69 (100%) Mus musculus
[UBERON:0004250] upper arm bone
MSI_000030986 Unreliable 763.4616 763.4616 ~ 763.4616
MzDiff: none
PA(17:0/PGJ2) (BioDeep_00000188501)
Formula: C40H69O10P (740.4628)
0.35 (100%) Macropus giganteus
[UBERON:0003027] cingulate cortex
MSI_000031108 Unreliable 763.4616 763.4616 ~ 763.4616
MzDiff: none
PA(17:0/PGJ2) (BioDeep_00000188501)
Formula: C40H69O10P (740.4628)
2.45 (100%) Macropus giganteus
[UBERON:0006093] precuneus cortex

Found 4 Sample Hits
Metabolite Species Sample
m/z_763.4583

Formula: - (n/a)
Adducts: (Ppm: )
Mus musculus (Lung)
image1
Resolution: 40μm, 187x165

Description

Fig. 2 MALDI-MSI data from the same mouse lung tissue analyzed in Fig. 1. A: Optical image of the post-MSI, H&E-stained tissue section. B–D, F–G: Ion images of (B) m/z 796.6855 ([U13C-DPPC+Na]+), (C) m/z 756.5514 ([PC32:0+Na]+), (D) m/z 765.6079 ([D9-PC32:0+Na]+), (F) m/z 754.5359 ([PC32:1+Na]+), and (G) m/z 763.5923 ([D9-PC32:1+Na]+). E, H: Ratio images of (E) [D9-PC32:0+Na]+:[PC32:0+Na]+ and (H) [D9-PC32:1+Na]+:[PC32:1+Na]+. Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. U13C-DPPC, universally 13C-labeled dipalmitoyl PC; PC, phosphatidylcholine; MSI, mass spectrometry imaging; H&E, hematoxylin and eosin. Fig 1-3, Fig S1-S3, S5

m/z_763.4537

Formula: - (n/a)
Adducts: (Ppm: )
Mus musculus (Lung)
image3
Resolution: 40μm, 146x190

Description

Fig. 4 MALDI-MSI data of mouse lung tissue after administration with D9-choline and U13C-DPPC–containing Poractant alfa surfactant (labels administered 12 h prior to tissue collection). Ion images of (A) m/z 796.6856 ([U13C-DPPC+Na]+), (B) m/z 756.5154 [PC32:0+Na]+), and (C) m/z 765.6079 ([D9-PC32:0+Na]+). D: Overlay image of [U13C-PC32:0+Na]+ (red) and [D9-PC32:0+Na]+ (green). Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. MSI, mass spectrometry imaging; PC, phosphatidylcholine; U13C-DPPC, universally 13C-labeled dipalmitoyl PC.

m/z_763.4542

Formula: - (n/a)
Adducts: (Ppm: )
Mus musculus (Lung)
image5
Resolution: 40μm, 163x183

Description

Supplementary Figure S8. MALDI-MSI data of mouse lung tissue administered with D9-choline and U 13C-DPPC–containing Poractant alfa surfactant (labels administered 18 h prior to sacrifice). Ion images of (a) m/z 796.6856 ([U13C-DPPC+Na]+), (b) m/z 756.5154 [PC32:0+Na]+ and (c) m/z 765.6079 ([D9-PC32:0+Na]+). (d) Overlay image of [U13C-DPPC+Na]+ (red) and [D9-PC32:0+Na]+ (green). Parts per million (ppm) mass errors are indicated in parentheses. All images were visualised using totalion-current normalisation and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0.

PG(i-12:0/PGE2)

Formula: C38H67O13P (762.4319)
Adducts: [M+H]+ (Ppm: 18.1)
Macropus giganteus (Brain)
170321_kangaroobrain-dan3-pos_maxof50.0_med1
Resolution: 50μm, 81x50

Description

Sample information Organism: Macropus giganteus (kangaroo) Organism part: Brain Condition: Wildtype Sample growth conditions: Wild