- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。
Found 8 Reference Ions Near m/z 761.4749
| NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
|---|---|---|---|---|---|
| MSI_000008990 Unreliable | 761.4689 | 761.4689 ~ 761.4689 MzDiff: none |
(1r,3ar,5ar,7r,9as,11ar)-3a,6,6,9a,11a-pentamethyl-1-[(2r)-6-methyl-5-methylidene-1-oxo-1-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}heptan-2-yl]-1h,2h,3h,4h,5h,5ah,7h,8h,9h,10h,11h-cyclopenta[a]phenanthren-7-yl 1-methyl (3s)-3-hydroxy-3-methylpentanedioate (BioDeep_00002063278) Formula: C43H68O11 (760.4761) |
3.17 (100%) | Mus musculus [UBERON:0004645] urinary bladder urothelium |
| MSI_000000823 Unavailable | 761.4689 | 761.4689 ~ 761.4689 MzDiff: none |
(1r,3ar,5ar,7r,9as,11ar)-3a,6,6,9a,11a-pentamethyl-1-[(2r)-6-methyl-5-methylidene-1-oxo-1-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}heptan-2-yl]-1h,2h,3h,4h,5h,5ah,7h,8h,9h,10h,11h-cyclopenta[a]phenanthren-7-yl 1-methyl (3s)-3-hydroxy-3-methylpentanedioate (BioDeep_00002063278) Formula: C43H68O11 (760.4761) |
-0.62 (100%) | Mus musculus [CL:0000066] epithelial cell |
| MSI_000026461 Unreliable | 761.471 | 761.471 ~ 761.471 MzDiff: none |
PA(18:2(9Z,11Z)/22:6(5Z,7Z,10Z,13Z,16Z,19Z)-OH(4)) (BioDeep_00000188961) Formula: C43H69O9P (760.4679) |
1.79 (100%) | Mus musculus [UBERON:0002048] lung |
| MSI_000026530 Unreliable | 761.4698 | 761.4698 ~ 761.4698 MzDiff: none |
PA(18:2(9Z,11Z)/22:6(5Z,7Z,10Z,13Z,16Z,19Z)-OH(4)) (BioDeep_00000188961) Formula: C43H69O9P (760.4679) |
1.79 (100%) | Mus musculus [UBERON:0002048] lung |
| MSI_000027798 Unreliable | 761.4661 | 761.4661 ~ 761.4661 MzDiff: none |
Not Annotated | 2.04 (0%) | Mus musculus [UBERON:0002048] lung |
| MSI_000061623 Unavailable | 761.4659 | 761.4659 ~ 761.4659 MzDiff: none |
Not Annotated | -0.35 (0%) | Mus musculus [UBERON:0000956] cerebral cortex |
| MSI_000062334 Unavailable | 761.4659 | 761.4659 ~ 761.4659 MzDiff: none |
Not Annotated | -0.35 (0%) | Mus musculus [UBERON:0001950] neocortex |
| MSI_000062768 Unavailable | 761.4659 | 761.4659 ~ 761.4659 MzDiff: none |
Not Annotated | -0.35 (0%) | Mus musculus [UBERON:0002421] hippocampal formation |
Found 4 Sample Hits
| Metabolite | Species | Sample | |
|---|---|---|---|
| PA(18:2(9Z,11Z)/22:6(5Z,7Z,10Z,13Z,16Z,19Z)-OH(4)) Formula: C43H69O9P (760.4679) Adducts: [M+H]+ (Ppm: 0.4) |
Mus musculus (Lung) |
image1Resolution: 40μm, 187x165
Fig. 2 MALDI-MSI data from the same mouse lung tissue analyzed in Fig. 1. A: Optical image of the post-MSI, H&E-stained tissue section. B–D, F–G: Ion images of (B) m/z 796.6855 ([U13C-DPPC+Na]+), (C) m/z 756.5514 ([PC32:0+Na]+), (D) m/z 765.6079 ([D9-PC32:0+Na]+), (F) m/z 754.5359 ([PC32:1+Na]+), and (G) m/z 763.5923 ([D9-PC32:1+Na]+). E, H: Ratio images of (E) [D9-PC32:0+Na]+:[PC32:0+Na]+ and (H) [D9-PC32:1+Na]+:[PC32:1+Na]+. Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. U13C-DPPC, universally 13C-labeled dipalmitoyl PC; PC, phosphatidylcholine; MSI, mass spectrometry imaging; H&E, hematoxylin and eosin.
Fig 1-3, Fig S1-S3, S5 |
|
| PA(18:2(9Z,11Z)/22:6(5Z,7Z,10Z,13Z,16Z,19Z)-OH(4)) Formula: C43H69O9P (760.4679) Adducts: [M+H]+ (Ppm: 5.5) |
Mus musculus (Lung) |
image3Resolution: 40μm, 146x190
Fig. 4 MALDI-MSI data of mouse lung tissue after administration with D9-choline and U13C-DPPC–containing Poractant alfa surfactant (labels administered 12 h prior to tissue collection). Ion images of (A) m/z 796.6856 ([U13C-DPPC+Na]+), (B) m/z 756.5154 [PC32:0+Na]+), and (C) m/z 765.6079 ([D9-PC32:0+Na]+). D: Overlay image of [U13C-PC32:0+Na]+ (red) and [D9-PC32:0+Na]+ (green). Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. MSI, mass spectrometry imaging; PC, phosphatidylcholine; U13C-DPPC, universally 13C-labeled dipalmitoyl PC. |
|
| PA(18:2(9Z,11Z)/22:6(5Z,7Z,10Z,13Z,16Z,19Z)-OH(4)) Formula: C43H69O9P (760.4679) Adducts: [M+H]+ (Ppm: 5.5) |
Mus musculus (Lung) |
image5Resolution: 40μm, 163x183
Supplementary Figure S8. MALDI-MSI data of mouse lung tissue administered with D9-choline and
U 13C-DPPC–containing Poractant alfa surfactant (labels administered 18 h prior to sacrifice). Ion
images of (a) m/z 796.6856 ([U13C-DPPC+Na]+), (b) m/z 756.5154 [PC32:0+Na]+ and (c) m/z 765.6079
([D9-PC32:0+Na]+). (d) Overlay image of [U13C-DPPC+Na]+ (red) and [D9-PC32:0+Na]+ (green).
Parts per million (ppm) mass errors are indicated in parentheses. All images were visualised using totalion-current normalisation and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. |
|
| PA(18:2(9Z,11Z)/22:6(5Z,7Z,10Z,13Z,16Z,19Z)-OH(4)) Formula: C43H69O9P (760.4679) Adducts: [M+H]+ (Ppm: 14.8) |
Macropus giganteus (Brain) |
170321_kangaroobrain-dan3-pos_maxof50.0_med1Resolution: 50μm, 81x50
Sample information
Organism: Macropus giganteus (kangaroo)
Organism part: Brain
Condition: Wildtype
Sample growth conditions: Wild |
|
