M/Z: 758.5826
Hit 3 annotations: PC(P-18:0/20:4(5Z,8Z,11Z,14Z))_[M+H-2H2O]+; SM(d19:0/18:1(12Z)-O(9S,10R))_[M]+; SM(d18:2(4E,14Z)/18:1(12Z)-2OH(9,10))_[M-H2O+NH4]+
- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。
Found 7 Reference Ions Near m/z 758.5826
| NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
|---|---|---|---|---|---|
| MSI_000020431 Reliable | 758.5793 | 758.5791 ~ 758.5796 MzDiff: 2.1 ppm |
PC(P-18:0/20:4(5Z,8Z,11Z,14Z)) (BioDeep_00000031857) Formula: C46H84NO7P (793.5985) |
4.36 (100%) | Rattus norvegicus [UBERON:0004359] corpus epididymis |
| MSI_000047636 Unreliable | 758.5784 | 758.5784 ~ 758.5784 MzDiff: none |
SM(d19:0/18:1(12Z)-O(9S,10R)) (BioDeep_00000215631) Formula: C42H83N2O7P (758.5938) |
2.2 (100%) | Homo sapiens [UBERON:0013067] colorectal mucosa |
| MSI_000052148 Unreliable | 758.58 | 758.58 ~ 758.58 MzDiff: none |
SM(d18:2(4E,14Z)/18:1(12Z)-2OH(9,10)) (BioDeep_00000215578) Formula: C41H79N2O8P (758.5574) |
2.3 (100%) | Homo sapiens [UBERON:0001052] rectum |
| MSI_000007208 | 758.5805 | 758.5801 ~ 758.5807 MzDiff: 2.2 ppm |
PC(P-18:0/20:4(5Z,8Z,11Z,14Z)) (BioDeep_00000031857) Formula: C46H84NO7P (793.5985) |
2.01 (100%) | Rattus norvegicus [UBERON:0004359] corpus epididymis |
| MSI_000043581 Unreliable | 758.5728 | 758.5728 ~ 758.5728 MzDiff: none |
PC(18:2(9Z,12Z)/16:0) (BioDeep_00000029408) Formula: C42H80NO8P (757.5621) |
1.43 (100%) | Homo sapiens [UBERON:0001043] esophagus |
| MSI_000028065 Unreliable | 758.5791 | 758.5791 ~ 758.5791 MzDiff: none |
Not Annotated | 2.16 (%) | Macropus giganteus [UBERON:0001891] midbrain |
| MSI_000031845 Unavailable | 758.5791 | 758.5791 ~ 758.5791 MzDiff: none |
Not Annotated | -0.22 (%) | Macropus giganteus [UBERON:0006093] precuneus cortex |
Found 13 Sample Hits
| Metabolite | Species | Sample | |
|---|---|---|---|
| PC(P-18:0/20:4(5Z,8Z,11Z,14Z)) Formula: C46H84NO7P (793.5985) Adducts: [M+H-2H2O]+ (Ppm: 6) |
Rattus norvegicus (Epididymis) |
epik_dhb_head_ito03_18Resolution: 17μm, 208x104
|
|
| PC(P-18:0/20:4(5Z,8Z,11Z,14Z)) Formula: C46H84NO7P (793.5985) Adducts: [M+H-2H2O]+ (Ppm: 6.7) |
Rattus norvegicus (Epididymis) |
epik_dhb_head_ito08_43Resolution: 17μm, 298x106
|
|
| PC(P-18:0/20:4(5Z,8Z,11Z,14Z)) Formula: C46H84NO7P (793.5985) Adducts: [M+H-2H2O]+ (Ppm: 5.2) |
Rattus norvegicus (Epididymis) |
epik_dhb_head_ito08_44Resolution: 17μm, 299x111
|
|
| PC(P-18:0/20:4(5Z,8Z,11Z,14Z)) Formula: C46H84NO7P (793.5985) Adducts: [M+H-2H2O]+ (Ppm: 4.8) |
Rattus norvegicus (Epididymis) |
epik_dhb_head_ito01_04Resolution: 17μm, 178x91
|
|
| PC(P-18:0/20:4(5Z,8Z,11Z,14Z)) Formula: C46H84NO7P (793.5985) Adducts: [M+H-2H2O]+ (Ppm: 5.1) |
Rattus norvegicus (Epididymis) |
epik_dhb_head_ito01_03Resolution: 17μm, 159x110
|
|
| PC(P-18:0/20:4(5Z,8Z,11Z,14Z)) Formula: C46H84NO7P (793.5985) Adducts: [M+H-2H2O]+ (Ppm: 6.3) |
Rattus norvegicus (normal) |
epik_dhb_head_ito01_05Resolution: 17μm, 183x105
|
|
| PC(P-18:0/20:4(5Z,8Z,11Z,14Z)) Formula: C46H84NO7P (793.5985) Adducts: [M+H-2H2O]+ (Ppm: 4.8) |
Rattus norvegicus (Epididymis) |
epik_dhb_head_ito01_06Resolution: 17μm, 183x103
|
|
| PC(P-18:0/20:4(5Z,8Z,11Z,14Z)) Formula: C46H84NO7P (793.5985) Adducts: [M+H-2H2O]+ (Ppm: 6) |
Rattus norvegicus (Epididymis) |
epik_dhb_head_ito03_14Resolution: 17μm, 205x103
|
|
| PC(P-18:0/20:4(5Z,8Z,11Z,14Z)) Formula: C46H84NO7P (793.5985) Adducts: [M+H-2H2O]+ (Ppm: 10.9) |
Mus musculus (Lung) |
image1Resolution: 40μm, 187x165
Fig. 2 MALDI-MSI data from the same mouse lung tissue analyzed in Fig. 1. A: Optical image of the post-MSI, H&E-stained tissue section. B–D, F–G: Ion images of (B) m/z 796.6855 ([U13C-DPPC+Na]+), (C) m/z 756.5514 ([PC32:0+Na]+), (D) m/z 765.6079 ([D9-PC32:0+Na]+), (F) m/z 754.5359 ([PC32:1+Na]+), and (G) m/z 763.5923 ([D9-PC32:1+Na]+). E, H: Ratio images of (E) [D9-PC32:0+Na]+:[PC32:0+Na]+ and (H) [D9-PC32:1+Na]+:[PC32:1+Na]+. Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. U13C-DPPC, universally 13C-labeled dipalmitoyl PC; PC, phosphatidylcholine; MSI, mass spectrometry imaging; H&E, hematoxylin and eosin.
Fig 1-3, Fig S1-S3, S5 |
|
| m/z_758.5791 Formula: - (n/a) Adducts: (Ppm: ) |
Macropus giganteus (Brain) |
170321_kangaroobrain-dan3-pos_maxof50.0_med1Resolution: 50μm, 81x50
Sample information
Organism: Macropus giganteus (kangaroo)
Organism part: Brain
Condition: Wildtype
Sample growth conditions: Wild |
|
| SM(d19:0/18:1(12Z)-O(9S,10R)) Formula: C42H83N2O7P (758.5938) Adducts: [M]+ (Ppm: 14) |
Homo sapiens (esophagus) |
LNTO22_1_3Resolution: 75μm, 121x68
|
|
| SM(d18:2(4E,14Z)/18:1(12Z)-2OH(9,10)) Formula: C41H79N2O8P (758.5574) Adducts: [M-H2O+NH4]+ (Ppm: 0.8) |
Homo sapiens (colorectal adenocarcinoma) |
439TopL, 409TopR, 429BottomL, 419BottomR-profileResolution: 17μm, 157x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| PC(P-18:0/20:4(5Z,8Z,11Z,14Z)) Formula: C46H84NO7P (793.5985) Adducts: [M+H-2H2O]+ (Ppm: 4.9) |
Homo sapiens (esophagus) |
LNTO22_2_1Resolution: 75μm, 89x88
|
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