- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。
Found 12 Reference Ions Near m/z 757.542
| NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
|---|---|---|---|---|---|
| MSI_000026397 Unreliable | 757.5505 | 757.5505 ~ 757.5506 MzDiff: 0.3 ppm |
PA(19:0/20:3(6,8,11)-OH(5)) (BioDeep_00000189502) Formula: C42H77O9P (756.5305) |
4.34 (67%) | Mus musculus [UBERON:0002048] lung |
| MSI_000026473 Unreliable | 757.5449 | 757.5449 ~ 757.545 MzDiff: 0.4 ppm |
Not Annotated | 3.83 (0%) | Mus musculus [UBERON:0002048] lung |
| MSI_000001387 Unavailable | 757.542 | 757.542 ~ 757.542 MzDiff: none |
PA(19:0/20:3(6,8,11)-OH(5)) (BioDeep_00000189502) Formula: C42H77O9P (756.5305) |
-0.65 (100%) | Mus musculus [UBERON:0001224] renal pelvis |
| MSI_000001430 Unavailable | 757.5502 | 757.5502 ~ 757.5502 MzDiff: none |
Not Annotated | -0.71 (0%) | Mus musculus [UBERON:0001224] renal pelvis |
| MSI_000001466 Unreliable | 757.5502 | 757.5502 ~ 757.5502 MzDiff: none |
Not Annotated | 1.88 (0%) | Mus musculus [UBERON:0001225] cortex of kidney |
| MSI_000001671 Unavailable | 757.542 | 757.542 ~ 757.542 MzDiff: none |
PA(19:0/20:3(6,8,11)-OH(5)) (BioDeep_00000189502) Formula: C42H77O9P (756.5305) |
-0.49 (100%) | Mus musculus [UBERON:0001225] cortex of kidney |
| MSI_000002178 Unavailable | 757.5502 | 757.5502 ~ 757.5502 MzDiff: none |
Not Annotated | -0.52 (0%) | Mus musculus [UBERON:0001293] outer medulla of kidney |
| MSI_000002294 Unavailable | 757.542 | 757.542 ~ 757.542 MzDiff: none |
PA(19:0/20:3(6,8,11)-OH(5)) (BioDeep_00000189502) Formula: C42H77O9P (756.5305) |
-0.63 (100%) | Mus musculus [UBERON:0001293] outer medulla of kidney |
| MSI_000028754 Unreliable | 757.5506 | 757.5506 ~ 757.5506 MzDiff: none |
Not Annotated | 0.42 (0%) | Macropus giganteus [UBERON:0001891] midbrain |
| MSI_000028780 Unreliable | 757.5456 | 757.5456 ~ 757.5456 MzDiff: none |
PA(19:0/20:3(6,8,11)-OH(5)) (BioDeep_00000189502) Formula: C42H77O9P (756.5305) |
0.37 (100%) | Macropus giganteus [UBERON:0001891] midbrain |
| MSI_000030206 Unreliable | 757.5456 | 757.5456 ~ 757.5456 MzDiff: none |
PA(19:0/20:3(6,8,11)-OH(5)) (BioDeep_00000189502) Formula: C42H77O9P (756.5305) |
2.1 (100%) | Macropus giganteus [UBERON:0003027] cingulate cortex |
| MSI_000031190 Unreliable | 757.5506 | 757.5506 ~ 757.5506 MzDiff: none |
Not Annotated | 2.03 (0%) | Macropus giganteus [UBERON:0006093] precuneus cortex |
Found 5 Sample Hits
| Metabolite | Species | Sample | |
|---|---|---|---|
| PA(19:0/20:3(6,8,11)-OH(5)) Formula: C42H77O9P (756.5305) Adducts: [M+H]+ (Ppm: 5.6) |
Mus musculus (Kidney) |
FULL_MS_centriod_CHCA_20210819Resolution: 17μm, 638x437
AP-MALDI instrument demo test, mass spectrum scan in centroid mode. |
|
| m/z_757.5457 Formula: - (n/a) Adducts: (Ppm: 0) |
Mus musculus (Lung) |
image1Resolution: 40μm, 187x165
Fig. 2 MALDI-MSI data from the same mouse lung tissue analyzed in Fig. 1. A: Optical image of the post-MSI, H&E-stained tissue section. B–D, F–G: Ion images of (B) m/z 796.6855 ([U13C-DPPC+Na]+), (C) m/z 756.5514 ([PC32:0+Na]+), (D) m/z 765.6079 ([D9-PC32:0+Na]+), (F) m/z 754.5359 ([PC32:1+Na]+), and (G) m/z 763.5923 ([D9-PC32:1+Na]+). E, H: Ratio images of (E) [D9-PC32:0+Na]+:[PC32:0+Na]+ and (H) [D9-PC32:1+Na]+:[PC32:1+Na]+. Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. U13C-DPPC, universally 13C-labeled dipalmitoyl PC; PC, phosphatidylcholine; MSI, mass spectrometry imaging; H&E, hematoxylin and eosin.
Fig 1-3, Fig S1-S3, S5 |
|
| m/z_757.5441 Formula: - (n/a) Adducts: (Ppm: 0) |
Mus musculus (Lung) |
image3Resolution: 40μm, 146x190
Fig. 4 MALDI-MSI data of mouse lung tissue after administration with D9-choline and U13C-DPPC–containing Poractant alfa surfactant (labels administered 12 h prior to tissue collection). Ion images of (A) m/z 796.6856 ([U13C-DPPC+Na]+), (B) m/z 756.5154 [PC32:0+Na]+), and (C) m/z 765.6079 ([D9-PC32:0+Na]+). D: Overlay image of [U13C-PC32:0+Na]+ (red) and [D9-PC32:0+Na]+ (green). Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. MSI, mass spectrometry imaging; PC, phosphatidylcholine; U13C-DPPC, universally 13C-labeled dipalmitoyl PC. |
|
| m/z_757.5454 Formula: - (n/a) Adducts: (Ppm: 0) |
Mus musculus (Lung) |
image5Resolution: 40μm, 163x183
Supplementary Figure S8. MALDI-MSI data of mouse lung tissue administered with D9-choline and
U 13C-DPPC–containing Poractant alfa surfactant (labels administered 18 h prior to sacrifice). Ion
images of (a) m/z 796.6856 ([U13C-DPPC+Na]+), (b) m/z 756.5154 [PC32:0+Na]+ and (c) m/z 765.6079
([D9-PC32:0+Na]+). (d) Overlay image of [U13C-DPPC+Na]+ (red) and [D9-PC32:0+Na]+ (green).
Parts per million (ppm) mass errors are indicated in parentheses. All images were visualised using totalion-current normalisation and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. |
|
| PA(19:0/20:3(6,8,11)-OH(5)) Formula: C42H77O9P (756.5305) Adducts: [M+H]+ (Ppm: 10.3) |
Macropus giganteus (Brain) |
170321_kangaroobrain-dan3-pos_maxof50.0_med1Resolution: 50μm, 81x50
Sample information
Organism: Macropus giganteus (kangaroo)
Organism part: Brain
Condition: Wildtype
Sample growth conditions: Wild |
|
