M/Z: 751.536
Hit 4 annotations: SM(d17:1/20:4(6E,8Z,11Z,14Z)+=O(5))_[M+H]+
; PG(16:0/18:0)_[M+H]+
; PA(18:1(9Z)/22:4(7Z,10Z,13Z,16Z))_[M+H]+
; PS(14:0/18:1(9Z))_[M+NH4]+
- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值,但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性,这个参考离子不应用于注释。
Found 19 Reference Ions Near m/z 751.536
NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
---|---|---|---|---|---|
MSI_000043885 Reliable | 751.5294 | 751.529 ~ 751.5297 MzDiff: 2.5 ppm |
PA(18:1(9Z)/22:4(7Z,10Z,13Z,16Z)) (BioDeep_00000107296) Formula: C43H75O8P (750.5199) |
7.49 (100%) | Homo sapiens [UBERON:0001043] esophagus |
MSI_000046873 Reliable | 751.5275 | 751.527 ~ 751.5278 MzDiff: 3.3 ppm |
PA(18:1(9Z)/22:4(7Z,10Z,13Z,16Z)) (BioDeep_00000107296) Formula: C43H75O8P (750.5199) |
8.02 (100%) | Homo sapiens [UBERON:0001043] esophagus |
MSI_000047065 Unreliable | 751.5287 | 751.5287 ~ 751.5287 MzDiff: none |
1,28-Dicaffeoyloctacosanediol (BioDeep_00000024304) Formula: C46H70O8 (750.507) |
2.89 (100%) | Homo sapiens [UBERON:0013067] colorectal mucosa |
MSI_000047153 Unreliable | 751.5339 | 751.5339 ~ 751.5339 MzDiff: none |
Not Annotated | 2.69 (%) | Homo sapiens [UBERON:0013067] colorectal mucosa |
MSI_000052531 Unreliable | 751.537 | 751.537 ~ 751.537 MzDiff: none |
PA(18:1(9Z)/22:4(7Z,10Z,13Z,16Z)) (BioDeep_00000107296) Formula: C43H75O8P (750.5199) |
1.78 (100%) | Homo sapiens [UBERON:0001052] rectum |
MSI_000046934 Unreliable | 751.5408 | 751.5408 ~ 751.5408 MzDiff: none |
PA(18:1(9Z)/22:4(7Z,10Z,13Z,16Z)) (BioDeep_00000107296) Formula: C43H75O8P (750.5199) |
3.12 (100%) | Homo sapiens [UBERON:0013067] colorectal mucosa |
MSI_000051955 Unreliable | 751.5439 | 751.5439 ~ 751.5439 MzDiff: none |
SM(d17:1/20:4(6E,8Z,11Z,14Z)+=O(5)) (BioDeep_00000215366) Formula: C42H75N2O7P (750.5312) |
2.37 (100%) | Homo sapiens [UBERON:0001052] rectum |
MSI_000021984 Unreliable | 751.5266 | 751.5266 ~ 751.5266 MzDiff: none |
PA(18:1(9Z)/22:4(7Z,10Z,13Z,16Z)) (BioDeep_00000107296) Formula: C43H75O8P (750.5199) |
0.51 (100%) | Mus musculus [UBERON:0001499] muscle of arm |
MSI_000065312 Unreliable | 751.5281 | 751.5281 ~ 751.5281 MzDiff: none |
PA(18:1(9Z)/22:4(7Z,10Z,13Z,16Z)) (BioDeep_00000107296) Formula: C43H75O8P (750.5199) |
2.18 (100%) | Homo sapiens [UBERON:0001155] colon |
MSI_000022970 Unreliable | 751.5266 | 751.5266 ~ 751.5266 MzDiff: none |
PA(18:1(9Z)/22:4(7Z,10Z,13Z,16Z)) (BioDeep_00000107296) Formula: C43H75O8P (750.5199) |
0.78 (100%) | Mus musculus [UBERON:0004250] upper arm bone |
MSI_000030194 Unreliable | 751.529 | 751.529 ~ 751.529 MzDiff: none |
PA(18:1(9Z)/22:4(7Z,10Z,13Z,16Z)) (BioDeep_00000107296) Formula: C43H75O8P (750.5199) |
2.13 (100%) | Macropus giganteus [UBERON:0003027] cingulate cortex |
MSI_000031620 Unreliable | 751.529 | 751.529 ~ 751.529 MzDiff: none |
PA(18:1(9Z)/22:4(7Z,10Z,13Z,16Z)) (BioDeep_00000107296) Formula: C43H75O8P (750.5199) |
0.16 (100%) | Macropus giganteus [UBERON:0006093] precuneus cortex |
MSI_000056233 Unavailable | 751.5304 | 751.5304 ~ 751.5304 MzDiff: none |
PA(18:1(9Z)/22:4(7Z,10Z,13Z,16Z)) (BioDeep_00000107296) Formula: C43H75O8P (750.5199) |
-0.58 (100%) | Homo sapiens [UBERON:0007779] transudate |
MSI_000029423 Unreliable | 751.5347 | 751.5347 ~ 751.5347 MzDiff: none |
PG(16:0/18:0) (BioDeep_00000019281) Formula: C40H79O10P (750.5411) |
0.95 (100%) | Macropus giganteus [UBERON:0002336] corpus callosum |
MSI_000030843 Unreliable | 751.5347 | 751.5347 ~ 751.5347 MzDiff: none |
PG(16:0/18:0) (BioDeep_00000019281) Formula: C40H79O10P (750.5411) |
0.82 (100%) | Macropus giganteus [UBERON:0003027] cingulate cortex |
MSI_000031462 Unreliable | 751.5347 | 751.5347 ~ 751.5347 MzDiff: none |
PG(16:0/18:0) (BioDeep_00000019281) Formula: C40H79O10P (750.5411) |
0.67 (100%) | Macropus giganteus [UBERON:0006093] precuneus cortex |
MSI_000061569 Unavailable | 751.536 | 751.536 ~ 751.536 MzDiff: none |
PG(16:0/18:0) (BioDeep_00000019281) Formula: C40H79O10P (750.5411) |
-0.35 (100%) | Mus musculus [UBERON:0000956] cerebral cortex |
MSI_000062395 Unavailable | 751.536 | 751.536 ~ 751.536 MzDiff: none |
PG(16:0/18:0) (BioDeep_00000019281) Formula: C40H79O10P (750.5411) |
-0.35 (100%) | Mus musculus [UBERON:0001950] neocortex |
MSI_000062825 Unavailable | 751.536 | 751.536 ~ 751.536 MzDiff: none |
PG(16:0/18:0) (BioDeep_00000019281) Formula: C40H79O10P (750.5411) |
-0.35 (100%) | Mus musculus [UBERON:0002421] hippocampal formation |
Found 9 Sample Hits
Metabolite | Species | Sample | |
---|---|---|---|
m/z_751.5351 Formula: - (n/a) Adducts: (Ppm: ) |
Rattus norvegicus (Epididymis) |
epik_dhb_head_ito01_06Resolution: 17μm, 183x103
|
|
SM(d17:1/20:4(6E,8Z,11Z,14Z)+=O(5)) Formula: C42H75N2O7P (750.5312) Adducts: [M+H]+ (Ppm: 11.6) |
Mus musculus (Lung) |
image3Resolution: 40μm, 146x190
Fig. 4 MALDI-MSI data of mouse lung tissue after administration with D9-choline and U13C-DPPC–containing Poractant alfa surfactant (labels administered 12 h prior to tissue collection). Ion images of (A) m/z 796.6856 ([U13C-DPPC+Na]+), (B) m/z 756.5154 [PC32:0+Na]+), and (C) m/z 765.6079 ([D9-PC32:0+Na]+). D: Overlay image of [U13C-PC32:0+Na]+ (red) and [D9-PC32:0+Na]+ (green). Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. MSI, mass spectrometry imaging; PC, phosphatidylcholine; U13C-DPPC, universally 13C-labeled dipalmitoyl PC. |
|
SM(d17:1/20:4(6E,8Z,11Z,14Z)+=O(5)) Formula: C42H75N2O7P (750.5312) Adducts: [M+H]+ (Ppm: 10.8) |
Mus musculus (Lung) |
image2Resolution: 40μm, 550x256
Supplementary Figure S6. Ion distribution images for (a) [PC36:4+Na]+ (m/z 804.5514) and (b)
[PC38:6+Na]+ (m/z 828.5515) obtained from mouse lung tissue collected 6 h after administration of D9-
choline and U13C-DPPC–containing CHF5633. Parts-per-million (ppm) mass errors are indicated in
parentheses. (c) Magnification of the boxed region in (a) with selected bronchiolar regions outlined in
white boxes. (d) The corresponding H&E-stained tissue section with the same selected bronchiolar
regions outlined in black boxes. These data demonstrate the co-localisation of the polyunsaturated lipids
PC36:4 and PC38:6 with the bronchiolar regions of the lung. All MSI images were visualised using
total ion current normalisation and hotspot removal (high quantile = 99%). |
|
PG(16:0/18:0) Formula: C40H79O10P (750.5411) Adducts: [M+H]+ (Ppm: 18.1) |
Macropus giganteus (Brain) |
170321_kangaroobrain-dan3-pos_maxof50.0_med1Resolution: 50μm, 81x50
Sample information
Organism: Macropus giganteus (kangaroo)
Organism part: Brain
Condition: Wildtype
Sample growth conditions: Wild |
|
m/z_751.5339 Formula: - (n/a) Adducts: (Ppm: ) |
Homo sapiens (colorectal adenocarcinoma) |
80TopL, 50TopR, 70BottomL, 60BottomR-profileResolution: 17μm, 137x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
PA(18:1(9Z)/22:4(7Z,10Z,13Z,16Z)) Formula: C43H75O8P (750.5199) Adducts: [M+H]+ (Ppm: 13) |
Homo sapiens (colorectal adenocarcinoma) |
439TopL, 409TopR, 429BottomL, 419BottomR-profileResolution: 17μm, 157x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
PS(14:0/18:1(9Z)) Formula: C38H72NO10P (733.4894) Adducts: [M+NH4]+ (Ppm: 12.3) |
Homo sapiens (NA) |
160TopL,130TopR,150BottomL,140BottomR-profileResolution: 17μm, 142x136
|
|
PA(18:1(9Z)/22:4(7Z,10Z,13Z,16Z)) Formula: C43H75O8P (750.5199) Adducts: [M+H]+ (Ppm: 16.1) |
Homo sapiens (NA) |
160TopL,130TopR,150BottomL,140BottomR-profileResolution: 17μm, 142x136
|
|
PG(16:0/18:0) Formula: C40H79O10P (750.5411) Adducts: [M+H]+ (Ppm: 16.4) |
Mus musculus (brain) |
Brain01_Bregma1-42_02_centroidResolution: 17μm, 434x258
|
|