- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。
Found 13 Reference Ions Near m/z 751.4126
| NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
|---|---|---|---|---|---|
| MSI_000061230 Reliable | 751.4075 | 751.4074 ~ 751.4078 MzDiff: 1.6 ppm |
Deacetylvinblastine (BioDeep_00000177991) Formula: C44H56N4O8 (768.4098) |
3.93 (100%) | Mus musculus [UBERON:0000956] cerebral cortex |
| MSI_000058618 Unreliable | 751.4077 | 751.4074 ~ 751.4078 MzDiff: 1.5 ppm |
Deacetylvinblastine (BioDeep_00000177991) Formula: C44H56N4O8 (768.4098) |
3.45 (100%) | Mus musculus [UBERON:0001950] neocortex |
| MSI_000021917 Unreliable | 751.4076 | 751.4076 ~ 751.4076 MzDiff: none |
Deacetylvinblastine (BioDeep_00000177991) Formula: C44H56N4O8 (768.4098) |
0.55 (100%) | Mus musculus [UBERON:0001499] muscle of arm |
| MSI_000002430 Unreliable | 751.4077 | 751.4077 ~ 751.4077 MzDiff: none |
Deacetylvinblastine (BioDeep_00000177991) Formula: C44H56N4O8 (768.4098) |
1.4 (100%) | Rattus norvegicus [UBERON:0001950] neocortex |
| MSI_000003189 Unreliable | 751.4077 | 751.4077 ~ 751.4077 MzDiff: none |
Deacetylvinblastine (BioDeep_00000177991) Formula: C44H56N4O8 (768.4098) |
1.18 (100%) | Rattus norvegicus [UBERON:0002037] cerebellum |
| MSI_000005324 Unavailable | 751.4077 | 751.4077 ~ 751.4077 MzDiff: none |
Deacetylvinblastine (BioDeep_00000177991) Formula: C44H56N4O8 (768.4098) |
-0.98 (100%) | Rattus norvegicus [UBERON:0002298] brainstem |
| MSI_000005632 Unavailable | 751.4077 | 751.4077 ~ 751.4077 MzDiff: none |
Deacetylvinblastine (BioDeep_00000177991) Formula: C44H56N4O8 (768.4098) |
-0.28 (100%) | Rattus norvegicus [UBERON:0002435] striatum |
| MSI_000022879 Unreliable | 751.4076 | 751.4076 ~ 751.4076 MzDiff: none |
Deacetylvinblastine (BioDeep_00000177991) Formula: C44H56N4O8 (768.4098) |
0.9 (100%) | Mus musculus [UBERON:0004250] upper arm bone |
| MSI_000059989 Unavailable | 751.4078 | 751.4078 ~ 751.4078 MzDiff: none |
Deacetylvinblastine (BioDeep_00000177991) Formula: C44H56N4O8 (768.4098) |
-0.79 (100%) | Mus musculus [UBERON:0002298] brainstem |
| MSI_000060602 Unavailable | 751.4078 | 751.4078 ~ 751.4078 MzDiff: none |
Deacetylvinblastine (BioDeep_00000177991) Formula: C44H56N4O8 (768.4098) |
-0.34 (100%) | Mus musculus [UBERON:0002421] hippocampal formation |
| MSI_000061617 Unavailable | 751.4184 | 751.4184 ~ 751.4184 MzDiff: none |
Polypodoside C (BioDeep_00000023564) Formula: C40H64O14 (768.4296) |
-0.35 (100%) | Mus musculus [UBERON:0000956] cerebral cortex |
| MSI_000062341 Unavailable | 751.4184 | 751.4184 ~ 751.4184 MzDiff: none |
Polypodoside C (BioDeep_00000023564) Formula: C40H64O14 (768.4296) |
-0.35 (100%) | Mus musculus [UBERON:0001950] neocortex |
| MSI_000062775 Unavailable | 751.4184 | 751.4184 ~ 751.4184 MzDiff: none |
Polypodoside C (BioDeep_00000023564) Formula: C40H64O14 (768.4296) |
-0.35 (100%) | Mus musculus [UBERON:0002421] hippocampal formation |
Found 4 Sample Hits
| Metabolite | Species | Sample | |
|---|---|---|---|
| Deacetylvinblastine Formula: C44H56N4O8 (768.4098) Adducts: [M+H-H2O]+ (Ppm: 1.6) |
Rattus norvegicus (Brain) |
Spectroswiss - sol_2x_br_2Resolution: 17μm, 488x193
|
|
| Deacetylvinblastine Formula: C44H56N4O8 (768.4098) Adducts: [M+H-H2O]+ (Ppm: 3.1) |
Mus musculus (Lung) |
image1Resolution: 40μm, 187x165
Fig. 2 MALDI-MSI data from the same mouse lung tissue analyzed in Fig. 1. A: Optical image of the post-MSI, H&E-stained tissue section. B–D, F–G: Ion images of (B) m/z 796.6855 ([U13C-DPPC+Na]+), (C) m/z 756.5514 ([PC32:0+Na]+), (D) m/z 765.6079 ([D9-PC32:0+Na]+), (F) m/z 754.5359 ([PC32:1+Na]+), and (G) m/z 763.5923 ([D9-PC32:1+Na]+). E, H: Ratio images of (E) [D9-PC32:0+Na]+:[PC32:0+Na]+ and (H) [D9-PC32:1+Na]+:[PC32:1+Na]+. Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. U13C-DPPC, universally 13C-labeled dipalmitoyl PC; PC, phosphatidylcholine; MSI, mass spectrometry imaging; H&E, hematoxylin and eosin.
Fig 1-3, Fig S1-S3, S5 |
|
| Polypodoside C Formula: C40H64O14 (768.4296) Adducts: [M+H-H2O]+ (Ppm: 18.2) |
Mus musculus (Lung) |
image1Resolution: 40μm, 187x165
Fig. 2 MALDI-MSI data from the same mouse lung tissue analyzed in Fig. 1. A: Optical image of the post-MSI, H&E-stained tissue section. B–D, F–G: Ion images of (B) m/z 796.6855 ([U13C-DPPC+Na]+), (C) m/z 756.5514 ([PC32:0+Na]+), (D) m/z 765.6079 ([D9-PC32:0+Na]+), (F) m/z 754.5359 ([PC32:1+Na]+), and (G) m/z 763.5923 ([D9-PC32:1+Na]+). E, H: Ratio images of (E) [D9-PC32:0+Na]+:[PC32:0+Na]+ and (H) [D9-PC32:1+Na]+:[PC32:1+Na]+. Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. U13C-DPPC, universally 13C-labeled dipalmitoyl PC; PC, phosphatidylcholine; MSI, mass spectrometry imaging; H&E, hematoxylin and eosin.
Fig 1-3, Fig S1-S3, S5 |
|
| Polypodoside C Formula: C40H64O14 (768.4296) Adducts: [M+H-H2O]+ (Ppm: 17.4) |
Mus musculus (Left upper arm) |
357_l_total ion countResolution: 50μm, 97x131
Diseased |
|
