- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。
Found 13 Reference Ions Near m/z 750.5362
| NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
|---|---|---|---|---|---|
| MSI_000065108 Reliable | 750.5444 | 750.544 ~ 750.5448 MzDiff: 3.3 ppm |
PE(18:0/20:4(5Z,8Z,11Z,14Z)) (BioDeep_00000014071) Formula: C43H78NO8P (767.5465) |
6.39 (100%) | Homo sapiens [UBERON:0001155] colon |
| MSI_000057448 Unreliable | 750.5445 | 750.5444 ~ 750.5448 MzDiff: 1.5 ppm |
PE(18:0/20:4(5Z,8Z,11Z,14Z)) (BioDeep_00000014071) Formula: C43H78NO8P (767.5465) |
1.09 (100%) | Homo sapiens [UBERON:0007779] transudate |
| MSI_000046905 Unreliable | 750.54 | 750.54 ~ 750.54 MzDiff: none |
PS(15:0/18:0) (BioDeep_00000104684) Formula: C39H76NO10P (749.5207) |
3.17 (100%) | Homo sapiens [UBERON:0013067] colorectal mucosa |
| MSI_000046990 Unreliable | 750.5331 | 750.5331 ~ 750.5331 MzDiff: none |
Not Annotated | 3.05 (0%) | Homo sapiens [UBERON:0013067] colorectal mucosa |
| MSI_000051795 Unreliable | 750.5431 | 750.5431 ~ 750.5431 MzDiff: none |
PE(18:0/20:4(5Z,8Z,11Z,14Z)) (BioDeep_00000014071) Formula: C43H78NO8P (767.5465) |
2.45 (100%) | Homo sapiens [UBERON:0001052] rectum |
| MSI_000052349 Unreliable | 750.5362 | 750.5362 ~ 750.5362 MzDiff: none |
PS(15:0/18:0) (BioDeep_00000104684) Formula: C39H76NO10P (749.5207) |
2.16 (100%) | Homo sapiens [UBERON:0001052] rectum |
| MSI_000008543 | 750.5426 | 750.5425 ~ 750.5427 MzDiff: 0.8 ppm |
PE(18:0/20:4(5Z,8Z,11Z,14Z)) (BioDeep_00000014071) Formula: C43H78NO8P (767.5465) |
2.56 (100%) | Rattus norvegicus [UBERON:0004360] cauda epididymis |
| MSI_000056723 Unreliable | 750.5425 | 750.5424 ~ 750.5426 MzDiff: 1.2 ppm |
PE(18:0/20:4(5Z,8Z,11Z,14Z)) (BioDeep_00000014071) Formula: C43H78NO8P (767.5465) |
2.94 (100%) | Homo sapiens [UBERON:0001043] esophagus |
| MSI_000029074 Unreliable | 750.5421 | 750.5421 ~ 750.5421 MzDiff: none |
PE(18:0/20:4(5Z,8Z,11Z,14Z)) (BioDeep_00000014071) Formula: C43H78NO8P (767.5465) |
2.16 (100%) | Macropus giganteus [UBERON:0002336] corpus callosum |
| MSI_000029104 Unreliable | 750.535 | 750.535 ~ 750.535 MzDiff: none |
Not Annotated | 2 (0%) | Macropus giganteus [UBERON:0002336] corpus callosum |
| MSI_000031874 Unavailable | 750.5421 | 750.5421 ~ 750.5421 MzDiff: none |
PE(18:0/20:4(5Z,8Z,11Z,14Z)) (BioDeep_00000014071) Formula: C43H78NO8P (767.5465) |
-0.25 (100%) | Macropus giganteus [UBERON:0006093] precuneus cortex |
| MSI_000050247 Unreliable | 750.542 | 750.542 ~ 750.542 MzDiff: none |
PE(18:0/20:4(5Z,8Z,11Z,14Z)) (BioDeep_00000014071) Formula: C43H78NO8P (767.5465) |
0.26 (100%) | Mytilus edulis [UBERON:0009120] gill filament |
| MSI_000050549 Unreliable | 750.542 | 750.542 ~ 750.542 MzDiff: none |
PE(18:0/20:4(5Z,8Z,11Z,14Z)) (BioDeep_00000014071) Formula: C43H78NO8P (767.5465) |
2.11 (100%) | Mytilus edulis [UBERON:2001856] gill ray |
Found 7 Sample Hits
| Metabolite | Species | Sample | |
|---|---|---|---|
| PE(18:0/20:4(5Z,8Z,11Z,14Z)) Formula: C43H78NO8P (767.5465) Adducts: [M+H-H2O]+ (Ppm: 15.4) |
Mus musculus (Lung) |
image2Resolution: 40μm, 550x256
Supplementary Figure S6. Ion distribution images for (a) [PC36:4+Na]+ (m/z 804.5514) and (b)
[PC38:6+Na]+ (m/z 828.5515) obtained from mouse lung tissue collected 6 h after administration of D9-
choline and U13C-DPPC–containing CHF5633. Parts-per-million (ppm) mass errors are indicated in
parentheses. (c) Magnification of the boxed region in (a) with selected bronchiolar regions outlined in
white boxes. (d) The corresponding H&E-stained tissue section with the same selected bronchiolar
regions outlined in black boxes. These data demonstrate the co-localisation of the polyunsaturated lipids
PC36:4 and PC38:6 with the bronchiolar regions of the lung. All MSI images were visualised using
total ion current normalisation and hotspot removal (high quantile = 99%). |
|
| m/z_750.535 Formula: - (n/a) Adducts: (Ppm: 0) |
Macropus giganteus (Brain) |
170321_kangaroobrain-dan3-pos_maxof50.0_med1Resolution: 50μm, 81x50
Sample information
Organism: Macropus giganteus (kangaroo)
Organism part: Brain
Condition: Wildtype
Sample growth conditions: Wild |
|
| m/z_750.5331 Formula: - (n/a) Adducts: (Ppm: 0) |
Homo sapiens (colorectal adenocarcinoma) |
80TopL, 50TopR, 70BottomL, 60BottomR-profileResolution: 17μm, 137x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| PS(15:0/18:0) Formula: C39H76NO10P (749.5207) Adducts: [M+H]+ (Ppm: 11.7) |
Homo sapiens (colorectal adenocarcinoma) |
520TopL, 490TopR, 510BottomL, 500BottomR-profileResolution: 17μm, 147x131
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| PS(15:0/18:0) Formula: C39H76NO10P (749.5207) Adducts: [M+H]+ (Ppm: 11) |
Homo sapiens (colorectal adenocarcinoma) |
439TopL, 409TopR, 429BottomL, 419BottomR-profileResolution: 17μm, 157x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| m/z_750.535 Formula: - (n/a) Adducts: (Ppm: 0) |
Homo sapiens (NA) |
160TopL,130TopR,150BottomL,140BottomR-profileResolution: 17μm, 142x136
|
|
| PE(18:0/20:4(5Z,8Z,11Z,14Z)) Formula: C43H78NO8P (767.5465) Adducts: [M+H-H2O]+ (Ppm: 3.4) |
Drosophila melanogaster (brain) |
Drosophila18Resolution: 5μm, 686x685
Sample information
Organism: Drosophila melanogaster
Organism part: Brain
Condition: Healthy
Sample preparation
Sample stabilisation: Frozen
Tissue modification: Frozen
MALDI matrix: 2,5-dihydroxybenzoic acid (DHB)
MALDI matrix application: TM sprayer
Solvent: Aceton/water
MS analysis
Polarity: Positive
Ionisation source: Prototype
Analyzer: Orbitrap
Pixel size: 5μm × 5μm
Annotation settings
m/z tolerance (ppm): 3
Analysis version: Original MSM
Pixel count: 469910
Imzml file size: 696.23 MB
Ibd file size: 814.11 MB |
|
