在BioDeep NovoCell知识数据库中,参考离子总共被划分为4个级别。
  • Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
  • Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
  • Unreliable: 这个参考离子具有较高的排名价值,但缺乏可重复性。
  • Unavailable: 由于排名价值低且缺乏可重复性,这个参考离子不应用于注释。

Found 5 Reference Ions Near m/z 750.5298
NovoCell ID m/z Mass Window Metabolite Ranking Anatomy Context
MSI_000046990 Unreliable 750.5331 750.5331 ~ 750.5331
MzDiff: none
Not Annotated 3.05 (0%) Homo sapiens
[UBERON:0013067] colorectal mucosa
MSI_000047314 Unreliable 750.5262 750.5262 ~ 750.5262
MzDiff: none
Salinomycin (BioDeep_00000183134)
Formula: C42H70O11 (750.4918)
2.4 (100%) Homo sapiens
[UBERON:0013067] colorectal mucosa
MSI_000052349 Unreliable 750.5362 750.5362 ~ 750.5362
MzDiff: none
PS(15:0/18:0) (BioDeep_00000104684)
Formula: C39H76NO10P (749.5207)
2.16 (100%) Homo sapiens
[UBERON:0001052] rectum
MSI_000029104 Unreliable 750.535 750.535 ~ 750.535
MzDiff: none
Not Annotated 2 (0%) Macropus giganteus
[UBERON:0002336] corpus callosum
MSI_000056218 Unavailable 750.5201 750.5201 ~ 750.5201
MzDiff: none
PS(15:0/18:0) (BioDeep_00000104684)
Formula: C39H76NO10P (749.5207)
-0.58 (100%) Homo sapiens
[UBERON:0007779] transudate

Found 7 Sample Hits
Metabolite Species Sample
PE(18:0/20:4(5Z,8Z,11Z,14Z))

Formula: C43H78NO8P (767.5465)
Adducts: [M+H-H2O]+ (Ppm: 15.4)
Mus musculus (Lung)
image2
Resolution: 40μm, 550x256

Description

Supplementary Figure S6. Ion distribution images for (a) [PC36:4+Na]+ (m/z 804.5514) and (b) [PC38:6+Na]+ (m/z 828.5515) obtained from mouse lung tissue collected 6 h after administration of D9- choline and U13C-DPPC–containing CHF5633. Parts-per-million (ppm) mass errors are indicated in parentheses. (c) Magnification of the boxed region in (a) with selected bronchiolar regions outlined in white boxes. (d) The corresponding H&E-stained tissue section with the same selected bronchiolar regions outlined in black boxes. These data demonstrate the co-localisation of the polyunsaturated lipids PC36:4 and PC38:6 with the bronchiolar regions of the lung. All MSI images were visualised using total ion current normalisation and hotspot removal (high quantile = 99%).

m/z_750.535

Formula: - (n/a)
Adducts: (Ppm: 0)
Macropus giganteus (Brain)
170321_kangaroobrain-dan3-pos_maxof50.0_med1
Resolution: 50μm, 81x50

Description

Sample information Organism: Macropus giganteus (kangaroo) Organism part: Brain Condition: Wildtype Sample growth conditions: Wild

Salinomycin

Formula: C42H70O11 (750.4918)
Adducts: [M-H2O+NH4]+ (Ppm: 14.9)
Homo sapiens (colorectal adenocarcinoma)
80TopL, 50TopR, 70BottomL, 60BottomR-profile
Resolution: 17μm, 137x136

Description

The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024).

m/z_750.5331

Formula: - (n/a)
Adducts: (Ppm: 0)
Homo sapiens (colorectal adenocarcinoma)
80TopL, 50TopR, 70BottomL, 60BottomR-profile
Resolution: 17μm, 137x136

Description

The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024).

Salinomycin

Formula: C42H70O11 (750.4918)
Adducts: [M-H2O+NH4]+ (Ppm: 19.7)
Homo sapiens (colorectal adenocarcinoma)
520TopL, 490TopR, 510BottomL, 500BottomR-profile
Resolution: 17μm, 147x131

Description

The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024).

Salinomycin

Formula: C42H70O11 (750.4918)
Adducts: [M-H2O+NH4]+ (Ppm: 19)
Homo sapiens (colorectal adenocarcinoma)
439TopL, 409TopR, 429BottomL, 419BottomR-profile
Resolution: 17μm, 157x136

Description

The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024).

Salinomycin

Formula: C42H70O11 (750.4918)
Adducts: [M-H2O+NH4]+ (Ppm: 17.4)
Homo sapiens (NA)
160TopL,130TopR,150BottomL,140BottomR-profile
Resolution: 17μm, 142x136

Description