M/Z: 748.5096
Hit 3 annotations: PS(15:0/18:1(11Z))_[M+H]+; Azithromycin_[M]+; PA(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))_[M]+
- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。
Found 10 Reference Ions Near m/z 748.5096
| NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
|---|---|---|---|---|---|
| MSI_000043665 Reliable | 748.5174 | 748.5171 ~ 748.5178 MzDiff: 3.2 ppm |
PS(15:0/18:1(11Z)) (BioDeep_00000104645) Formula: C39H74NO10P (747.505) |
8.66 (33%) | Homo sapiens [UBERON:0001043] esophagus |
| MSI_000055601 Reliable | 748.5024 | 748.5021 ~ 748.503 MzDiff: 3.6 ppm |
PS(15:0/18:1(11Z)) (BioDeep_00000104645) Formula: C39H74NO10P (747.505) |
5.59 (58%) | Homo sapiens [UBERON:0001043] esophagus |
| MSI_000043260 Reliable | 748.5006 | 748.5 ~ 748.501 MzDiff: 3.9 ppm |
Azithromycin (BioDeep_00000002907) Formula: C38H72N2O12 (748.5085) |
13.96 (36%) | Homo sapiens [UBERON:0001043] esophagus |
| MSI_000058320 Unreliable | 748.5159 | 748.5155 ~ 748.516 MzDiff: 2.2 ppm |
Not Annotated | 5.33 (0%) | Homo sapiens [UBERON:0001043] esophagus |
| MSI_000065278 Unreliable | 748.5157 | 748.5152 ~ 748.5159 MzDiff: 2.8 ppm |
PS(15:0/18:1(11Z)) (BioDeep_00000104645) Formula: C39H74NO10P (747.505) |
4.03 (100%) | Homo sapiens [UBERON:0001155] colon |
| MSI_000065762 Unreliable | 748.5009 | 748.5008 ~ 748.5009 MzDiff: 0.4 ppm |
PS(16:0/20:4(5Z,8Z,11Z,14Z)) (BioDeep_00000032585) Formula: C42H74NO10P (783.505) |
1.34 (100%) | Homo sapiens [UBERON:0001155] colon |
| MSI_000047605 Unreliable | 748.5133 | 748.5133 ~ 748.5133 MzDiff: none |
Azithromycin (BioDeep_00000002907) Formula: C38H72N2O12 (748.5085) |
2.21 (100%) | Homo sapiens [UBERON:0013067] colorectal mucosa |
| MSI_000051887 Unreliable | 748.5164 | 748.5164 ~ 748.5164 MzDiff: none |
Azithromycin (BioDeep_00000002907) Formula: C38H72N2O12 (748.5085) |
2.4 (100%) | Homo sapiens [UBERON:0001052] rectum |
| MSI_000052329 Unreliable | 748.5096 | 748.5096 ~ 748.5096 MzDiff: none |
PA(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) (BioDeep_00000107249) Formula: C43H73O8P (748.5043) |
2.19 (100%) | Homo sapiens [UBERON:0001052] rectum |
| MSI_000056287 Unavailable | 748.5027 | 748.5027 ~ 748.5027 MzDiff: none |
PS(16:0/20:4(5Z,8Z,11Z,14Z)) (BioDeep_00000032585) Formula: C42H74NO10P (783.505) |
-0.59 (100%) | Homo sapiens [UBERON:0007779] transudate |
Found 7 Sample Hits
| Metabolite | Species | Sample | |
|---|---|---|---|
| PS(15:0/18:1(11Z)) Formula: C39H74NO10P (747.505) Adducts: [M+H]+ (Ppm: 12.5) |
Mus musculus (Lung) |
image2Resolution: 40μm, 550x256
Supplementary Figure S6. Ion distribution images for (a) [PC36:4+Na]+ (m/z 804.5514) and (b)
[PC38:6+Na]+ (m/z 828.5515) obtained from mouse lung tissue collected 6 h after administration of D9-
choline and U13C-DPPC–containing CHF5633. Parts-per-million (ppm) mass errors are indicated in
parentheses. (c) Magnification of the boxed region in (a) with selected bronchiolar regions outlined in
white boxes. (d) The corresponding H&E-stained tissue section with the same selected bronchiolar
regions outlined in black boxes. These data demonstrate the co-localisation of the polyunsaturated lipids
PC36:4 and PC38:6 with the bronchiolar regions of the lung. All MSI images were visualised using
total ion current normalisation and hotspot removal (high quantile = 99%). |
|
| m/z_748.5065 Formula: - (n/a) Adducts: (Ppm: 0) |
Homo sapiens (colorectal adenocarcinoma) |
80TopL, 50TopR, 70BottomL, 60BottomR-profileResolution: 17μm, 137x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| Azithromycin Formula: C38H72N2O12 (748.5085) Adducts: [M]+ (Ppm: 7.1) |
Homo sapiens (colorectal adenocarcinoma) |
80TopL, 50TopR, 70BottomL, 60BottomR-profileResolution: 17μm, 137x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| PA(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) Formula: C43H73O8P (748.5043) Adducts: [M]+ (Ppm: 8.6) |
Homo sapiens (colorectal adenocarcinoma) |
520TopL, 490TopR, 510BottomL, 500BottomR-profileResolution: 17μm, 147x131
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| PA(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) Formula: C43H73O8P (748.5043) Adducts: [M]+ (Ppm: 7.8) |
Homo sapiens (colorectal adenocarcinoma) |
439TopL, 409TopR, 429BottomL, 419BottomR-profileResolution: 17μm, 157x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| m/z_748.5054 Formula: - (n/a) Adducts: (Ppm: 0) |
Homo sapiens (NA) |
160TopL,130TopR,150BottomL,140BottomR-profileResolution: 17μm, 142x136
|
|
| PS(15:0/18:1(11Z)) Formula: C39H74NO10P (747.505) Adducts: [M+H]+ (Ppm: 5.6) |
Homo sapiens (colorectal adenocarcinoma) |
120TopL, 90TopR, 110BottomL, 100BottomR-centroidResolution: 50μm, 132x136
|
|
