M/Z: 747.5221
Hit 4 annotations: PS(15:0/18:1(11Z))_[M-H2O+NH4]+; PG(16:0/18:2(9Z,12Z))_[M+H]+; Narasin_[M+H-H2O]+; Azitromycin_[M+H]+
- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。
Found 15 Reference Ions Near m/z 747.5221
| NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
|---|---|---|---|---|---|
| MSI_000043149 Reliable | 747.5194 | 747.519 ~ 747.52 MzDiff: 4.0 ppm |
PG(16:0/18:2(9Z,12Z)) (BioDeep_00000019282) Formula: C40H75O10P (746.5098) |
12.14 (94%) | Homo sapiens [UBERON:0001043] esophagus |
| MSI_000043248 Reliable | 747.5194 | 747.519 ~ 747.52 MzDiff: 4.0 ppm |
PG(16:0/18:2(9Z,12Z)) (BioDeep_00000019282) Formula: C40H75O10P (746.5098) |
12.14 (94%) | Homo sapiens [UBERON:0001043] esophagus |
| MSI_000043757 Reliable | 747.5184 | 747.518 ~ 747.5189 MzDiff: 3.7 ppm |
PG(16:0/18:2(9Z,12Z)) (BioDeep_00000019282) Formula: C40H75O10P (746.5098) |
11.12 (64%) | Homo sapiens [UBERON:0001043] esophagus |
| MSI_000047140 Unreliable | 747.5153 | 747.5153 ~ 747.5153 MzDiff: none |
Narasin (BioDeep_00000017926) Formula: C43H72O11 (764.5074) |
2.72 (100%) | Homo sapiens [UBERON:0013067] colorectal mucosa |
| MSI_000056766 Unreliable | 747.5166 | 747.5161 ~ 747.5169 MzDiff: 3.5 ppm |
PG(16:0/18:2(9Z,12Z)) (BioDeep_00000019282) Formula: C40H75O10P (746.5098) |
2.48 (100%) | Homo sapiens [UBERON:0001043] esophagus |
| MSI_000065447 Unreliable | 747.5176 | 747.5175 ~ 747.5178 MzDiff: 1.1 ppm |
PG(16:0/18:2(9Z,12Z)) (BioDeep_00000019282) Formula: C40H75O10P (746.5098) |
2.67 (100%) | Homo sapiens [UBERON:0001155] colon |
| MSI_000051646 Unreliable | 747.5184 | 747.5184 ~ 747.5184 MzDiff: none |
Narasin (BioDeep_00000017926) Formula: C43H72O11 (764.5074) |
2.98 (100%) | Homo sapiens [UBERON:0001052] rectum |
| MSI_000047156 Unreliable | 747.5221 | 747.5221 ~ 747.5221 MzDiff: none |
Azitromycin (BioDeep_00000177001) Formula: C39H74N2O11 (746.5292) |
2.68 (100%) | Homo sapiens [UBERON:0013067] colorectal mucosa |
| MSI_000051663 Unreliable | 747.5252 | 747.5252 ~ 747.5252 MzDiff: none |
Azitromycin (BioDeep_00000177001) Formula: C39H74N2O11 (746.5292) |
2.75 (100%) | Homo sapiens [UBERON:0001052] rectum |
| MSI_000047230 Unreliable | 747.529 | 747.529 ~ 747.529 MzDiff: none |
SM(d18:0/PGJ2) (BioDeep_00000215463) Formula: C43H79N2O8P (782.5574) |
2.53 (100%) | Homo sapiens [UBERON:0013067] colorectal mucosa |
| MSI_000051867 Unreliable | 747.532 | 747.532 ~ 747.532 MzDiff: none |
Not Annotated | 2.4 (%) | Homo sapiens [UBERON:0001052] rectum |
| MSI_000026846 Unreliable | 747.5129 | 747.5129 ~ 747.5129 MzDiff: none |
PG(16:0/18:2(9Z,12Z)) (BioDeep_00000019282) Formula: C40H75O10P (746.5098) |
1.78 (100%) | Mus musculus [UBERON:0002048] lung |
| MSI_000026891 Unreliable | 747.5153 | 747.5153 ~ 747.5153 MzDiff: none |
PG(16:0/18:2(9Z,12Z)) (BioDeep_00000019282) Formula: C40H75O10P (746.5098) |
1.78 (100%) | Mus musculus [UBERON:0002048] lung |
| MSI_000025795 Unreliable | 747.517 | 747.517 ~ 747.517 MzDiff: none |
PS(15:0/18:1(11Z)) (BioDeep_00000104645) Formula: C39H74NO10P (747.505) |
2.09 (100%) | Mus musculus [UBERON:0000913] interstitial fluid |
| MSI_000056122 Unavailable | 747.5205 | 747.5205 ~ 747.5205 MzDiff: none |
PG(16:0/18:2(9Z,12Z)) (BioDeep_00000019282) Formula: C40H75O10P (746.5098) |
-0.55 (100%) | Homo sapiens [UBERON:0007779] transudate |
Found 25 Sample Hits
| Metabolite | Species | Sample | |
|---|---|---|---|
| PS(15:0/18:1(11Z)) Formula: C39H74NO10P (747.505) Adducts: [M-H2O+NH4]+ (Ppm: 15.1) |
Mus musculus (Lung) |
image1Resolution: 40μm, 187x165
Fig. 2 MALDI-MSI data from the same mouse lung tissue analyzed in Fig. 1. A: Optical image of the post-MSI, H&E-stained tissue section. B–D, F–G: Ion images of (B) m/z 796.6855 ([U13C-DPPC+Na]+), (C) m/z 756.5514 ([PC32:0+Na]+), (D) m/z 765.6079 ([D9-PC32:0+Na]+), (F) m/z 754.5359 ([PC32:1+Na]+), and (G) m/z 763.5923 ([D9-PC32:1+Na]+). E, H: Ratio images of (E) [D9-PC32:0+Na]+:[PC32:0+Na]+ and (H) [D9-PC32:1+Na]+:[PC32:1+Na]+. Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. U13C-DPPC, universally 13C-labeled dipalmitoyl PC; PC, phosphatidylcholine; MSI, mass spectrometry imaging; H&E, hematoxylin and eosin.
Fig 1-3, Fig S1-S3, S5 |
|
| PG(16:0/18:2(9Z,12Z)) Formula: C40H75O10P (746.5098) Adducts: [M+H]+ (Ppm: 2.9) |
Homo sapiens (esophagus) |
LNTO22_1_3Resolution: 75μm, 121x68
|
|
| Narasin Formula: C43H72O11 (764.5074) Adducts: [M+H-H2O]+ (Ppm: 18.4) |
Homo sapiens (esophagus) |
LNTO29_16_2Resolution: 17μm, 95x101
|
|
| PG(16:0/18:2(9Z,12Z)) Formula: C40H75O10P (746.5098) Adducts: [M+H]+ (Ppm: 4) |
Homo sapiens (esophagus) |
LNTO22_1_9Resolution: 75μm, 89x74
|
|
| Azitromycin Formula: C39H74N2O11 (746.5292) Adducts: [M+H]+ (Ppm: 19.3) |
Homo sapiens (colorectal adenocarcinoma) |
80TopL, 50TopR, 70BottomL, 60BottomR-profileResolution: 17μm, 137x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| Narasin Formula: C43H72O11 (764.5074) Adducts: [M+H-H2O]+ (Ppm: 19.7) |
Homo sapiens (colorectal adenocarcinoma) |
520TopL, 490TopR, 510BottomL, 500BottomR-profileResolution: 17μm, 147x131
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| Azitromycin Formula: C39H74N2O11 (746.5292) Adducts: [M+H]+ (Ppm: 14.3) |
Homo sapiens (colorectal adenocarcinoma) |
520TopL, 490TopR, 510BottomL, 500BottomR-profileResolution: 17μm, 147x131
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| Narasin Formula: C43H72O11 (764.5074) Adducts: [M+H-H2O]+ (Ppm: 19.1) |
Homo sapiens (colorectal adenocarcinoma) |
439TopL, 409TopR, 429BottomL, 419BottomR-profileResolution: 17μm, 157x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| Azitromycin Formula: C39H74N2O11 (746.5292) Adducts: [M+H]+ (Ppm: 16.6) |
Homo sapiens (NA) |
160TopL,130TopR,150BottomL,140BottomR-profileResolution: 17μm, 142x136
|
|
| PG(16:0/18:2(9Z,12Z)) Formula: C40H75O10P (746.5098) Adducts: [M+H]+ (Ppm: 3.4) |
Homo sapiens (esophagus) |
LNTO26_7_1Resolution: 17μm, 75x74
|
|
| PG(16:0/18:2(9Z,12Z)) Formula: C40H75O10P (746.5098) Adducts: [M+H]+ (Ppm: 4.6) |
Homo sapiens (esophagus) |
LNTO26_7_2Resolution: 17μm, 135x101
|
|
| PG(16:0/18:2(9Z,12Z)) Formula: C40H75O10P (746.5098) Adducts: [M+H]+ (Ppm: 2.8) |
Homo sapiens (esophagus) |
LNTO26_7_3Resolution: 75μm, 82x88
|
|
| PG(16:0/18:2(9Z,12Z)) Formula: C40H75O10P (746.5098) Adducts: [M+H]+ (Ppm: 1.3) |
Homo sapiens (esophagus) |
TO40TResolution: 17μm, 82x74
|
|
| PG(16:0/18:2(9Z,12Z)) Formula: C40H75O10P (746.5098) Adducts: [M+H]+ (Ppm: 1.3) |
Homo sapiens (esophagus) |
LNTO30_8M_2Resolution: 75μm, 108x68
|
|
| PG(16:0/18:2(9Z,12Z)) Formula: C40H75O10P (746.5098) Adducts: [M+H]+ (Ppm: 1.2) |
Homo sapiens (esophagus) |
LNTO30_8M_3Resolution: 75μm, 69x54
|
|
| Narasin Formula: C43H72O11 (764.5074) Adducts: [M+H-H2O]+ (Ppm: 18.8) |
Homo sapiens (esophagus) |
LNTO30_8M_5Resolution: 75μm, 56x54
|
|
| PG(16:0/18:2(9Z,12Z)) Formula: C40H75O10P (746.5098) Adducts: [M+H]+ (Ppm: 3.7) |
Homo sapiens (esophagus) |
LNTO22_1_5Resolution: 75μm, 135x94
|
|
| Narasin Formula: C43H72O11 (764.5074) Adducts: [M+H-H2O]+ (Ppm: 19.9) |
Homo sapiens (esophagus) |
LNTO22_1_7Resolution: 75μm, 69x54
|
|
| PG(16:0/18:2(9Z,12Z)) Formula: C40H75O10P (746.5098) Adducts: [M+H]+ (Ppm: 3) |
Homo sapiens (esophagus) |
LNTO22_2_1Resolution: 75μm, 89x88
|
|
| PG(16:0/18:2(9Z,12Z)) Formula: C40H75O10P (746.5098) Adducts: [M+H]+ (Ppm: 3.4) |
Homo sapiens (esophagus) |
LNTO22_2_2Resolution: 75μm, 135x94
|
|
| PG(16:0/18:2(9Z,12Z)) Formula: C40H75O10P (746.5098) Adducts: [M+H]+ (Ppm: 3.2) |
Homo sapiens (esophagus) |
LNTO26_16_1Resolution: 75μm, 95x88
|
|
| PG(16:0/18:2(9Z,12Z)) Formula: C40H75O10P (746.5098) Adducts: [M+H]+ (Ppm: 1.6) |
Homo sapiens (esophagus) |
LNTO30_7_1Resolution: 75μm, 69x68
|
|
| PG(16:0/18:2(9Z,12Z)) Formula: C40H75O10P (746.5098) Adducts: [M+H]+ (Ppm: 1.3) |
Homo sapiens (esophagus) |
LNTO30_7_2Resolution: 75μm, 82x68
|
|
| PG(16:0/18:2(9Z,12Z)) Formula: C40H75O10P (746.5098) Adducts: [M+H]+ (Ppm: 1.7) |
Homo sapiens (colorectal adenocarcinoma) |
200TopL, 170TopR, 190BottomL, 180BottomR-centroidResolution: 50μm, 132x126
|
|
| PG(16:0/18:2(9Z,12Z)) Formula: C40H75O10P (746.5098) Adducts: [M+H]+ (Ppm: 1.6) |
Homo sapiens (colorectal adenocarcinoma) |
120TopL, 90TopR, 110BottomL, 100BottomR-centroidResolution: 50μm, 132x136
|
|
