M/Z: 718.4504


Hit 1 annotations:  PS(14:1(9Z)/20:4(5Z,8Z,11Z,14Z))_[M+H-2H2O]+


在BioDeep NovoCell知识数据库中,参考离子总共被划分为4个级别。
  • Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
  • Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
  • Unreliable: 这个参考离子具有较高的排名价值,但缺乏可重复性。
  • Unavailable: 由于排名价值低且缺乏可重复性,这个参考离子不应用于注释。

Found 2 Reference Ions Near m/z 718.4504
NovoCell ID m/z Mass Window Metabolite Ranking Anatomy Context
MSI_000025470 Unreliable 718.4565 718.4564 ~ 718.4569
MzDiff: 2.0 ppm
PS(14:1(9Z)/20:4(5Z,8Z,11Z,14Z)) (BioDeep_00000032577)
Formula: C40H68NO10P (753.4581)
2.78 (75%) Mus musculus
[UBERON:0000913] interstitial fluid
MSI_000025797 Unreliable 718.4589 718.4589 ~ 718.4589
MzDiff: 0.1 ppm
PA(14:0/PGF2alpha) (BioDeep_00000187980)
Formula: C37H67O11P (718.4421)
2.09 (100%) Mus musculus
[UBERON:0000913] interstitial fluid

Found 4 Sample Hits
Metabolite Species Sample
PS(14:1(9Z)/20:4(5Z,8Z,11Z,14Z))

Formula: C40H68NO10P (753.4581)
Adducts: [M+H-2H2O]+ (Ppm: 17.7)
Mus musculus (Lung)
image3
Resolution: 40μm, 146x190

Description

Fig. 4 MALDI-MSI data of mouse lung tissue after administration with D9-choline and U13C-DPPC–containing Poractant alfa surfactant (labels administered 12 h prior to tissue collection). Ion images of (A) m/z 796.6856 ([U13C-DPPC+Na]+), (B) m/z 756.5154 [PC32:0+Na]+), and (C) m/z 765.6079 ([D9-PC32:0+Na]+). D: Overlay image of [U13C-PC32:0+Na]+ (red) and [D9-PC32:0+Na]+ (green). Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. MSI, mass spectrometry imaging; PC, phosphatidylcholine; U13C-DPPC, universally 13C-labeled dipalmitoyl PC.

PS(14:1(9Z)/20:4(5Z,8Z,11Z,14Z))

Formula: C40H68NO10P (753.4581)
Adducts: [M+H-2H2O]+ (Ppm: 17)
Mus musculus (Lung)
image5
Resolution: 40μm, 163x183

Description

Supplementary Figure S8. MALDI-MSI data of mouse lung tissue administered with D9-choline and U 13C-DPPC–containing Poractant alfa surfactant (labels administered 18 h prior to sacrifice). Ion images of (a) m/z 796.6856 ([U13C-DPPC+Na]+), (b) m/z 756.5154 [PC32:0+Na]+ and (c) m/z 765.6079 ([D9-PC32:0+Na]+). (d) Overlay image of [U13C-DPPC+Na]+ (red) and [D9-PC32:0+Na]+ (green). Parts per million (ppm) mass errors are indicated in parentheses. All images were visualised using totalion-current normalisation and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0.

m/z_718.4564

Formula: - (n/a)
Adducts: (Ppm: 0)
Mus musculus (Lung)
image2
Resolution: 40μm, 550x256

Description

Supplementary Figure S6. Ion distribution images for (a) [PC36:4+Na]+ (m/z 804.5514) and (b) [PC38:6+Na]+ (m/z 828.5515) obtained from mouse lung tissue collected 6 h after administration of D9- choline and U13C-DPPC–containing CHF5633. Parts-per-million (ppm) mass errors are indicated in parentheses. (c) Magnification of the boxed region in (a) with selected bronchiolar regions outlined in white boxes. (d) The corresponding H&E-stained tissue section with the same selected bronchiolar regions outlined in black boxes. These data demonstrate the co-localisation of the polyunsaturated lipids PC36:4 and PC38:6 with the bronchiolar regions of the lung. All MSI images were visualised using total ion current normalisation and hotspot removal (high quantile = 99%).

PS(14:1(9Z)/20:4(5Z,8Z,11Z,14Z))

Formula: C40H68NO10P (753.4581)
Adducts: [M+H-2H2O]+ (Ppm: 8.6)
Homo sapiens (esophagus)
LNTO22_1_4
Resolution: 17μm, 82x80

Description