M/Z: 673.4357

Hit 2 annotations: PA(14:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))_[M+H-H2O]+; 2-(4-Hydroxy-1,3-thiazol-3-ium-3-yl)ethyl [2-(octadecylcarbamoyloxymethyl)oxolan-2-yl]methyl phosphate_[M+K]+

在BioDeep NovoCell知识数据库中，参考离子总共被划分为4个级别。

Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。

Found 3 Reference Ions Near m/z 673.4357

NovoCell ID	m/z	Mass Window	Metabolite	Ranking	Anatomy Context
MSI_000027906 Unreliable	673.4293	673.4293 ~ 673.4293 MzDiff: `none`	2-(4-Hydroxy-1,3-thiazol-3-ium-3-yl)ethyl [2-(octadecylcarbamoyloxymethyl)oxolan-2-yl]methyl phosphate (BioDeep_00000183952) Formula: C30H55N2O8PS (634.3417)	2.01 (100%)	Mus musculus [UBERON:0002048] lung
MSI_000024758 Unreliable	673.4357	673.4357 ~ 673.4357 MzDiff: `none`	PA(14:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) (BioDeep_00000107165) Formula: C39H63O8P (690.426)	1.77 (100%)	Mus musculus [UBERON:0004269] upper arm connective tissue
MSI_000023424 Unreliable	673.4437	673.4437 ~ 673.4437 MzDiff: `none`	Vinaginsenoside R12 (BioDeep_00000025939) Formula: C36H64O11 (672.4448)	1.65 (100%)	Mus musculus [UBERON:0004263] upper arm skin

Found 2 Sample Hits

Metabolite	Species	Sample
PA(14:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z)) Formula: C39H63O8P (690.426) Adducts: [M+H-H2O]+ (Ppm: 19.2)	Mus musculus (Left upper arm)	357_l_total ion count Resolution: 50μm, 97x131 Description Diseased
2-(4-Hydroxy-1,3-thiazol-3-ium-3-yl)ethyl [2-(octadecylcarbamoyloxymethyl)oxolan-2-yl]methyl phosphate Formula: C30H55N2O8PS (634.3417) Adducts: [M+K]+ (Ppm: 15)	Mus musculus (Lung)	image2 Resolution: 40μm, 550x256 Description Supplementary Figure S6. Ion distribution images for (a) [PC36:4+Na]+ (m/z 804.5514) and (b) [PC38:6+Na]+ (m/z 828.5515) obtained from mouse lung tissue collected 6 h after administration of D9- choline and U13C-DPPC–containing CHF5633. Parts-per-million (ppm) mass errors are indicated in parentheses. (c) Magnification of the boxed region in (a) with selected bronchiolar regions outlined in white boxes. (d) The corresponding H&E-stained tissue section with the same selected bronchiolar regions outlined in black boxes. These data demonstrate the co-localisation of the polyunsaturated lipids PC36:4 and PC38:6 with the bronchiolar regions of the lung. All MSI images were visualised using total ion current normalisation and hotspot removal (high quantile = 99%).

Metabolite

Species

Sample

PA(14:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))

Formula: C39H63O8P (690.426)
Adducts: [M+H-H2O]+ (Ppm: 19.2)

Mus musculus (Left upper arm)

357_l_total ion count

Resolution: 50μm, 97x131

Description

Diseased

2-(4-Hydroxy-1,3-thiazol-3-ium-3-yl)ethyl [2-(octadecylcarbamoyloxymethyl)oxolan-2-yl]methyl phosphate

Formula: C30H55N2O8PS (634.3417)
Adducts: [M+K]+ (Ppm: 15)

Mus musculus (Lung)

image2

Resolution: 40μm, 550x256

Description

Supplementary Figure S6. Ion distribution images for (a) [PC36:4+Na]+ (m/z 804.5514) and (b) [PC38:6+Na]+ (m/z 828.5515) obtained from mouse lung tissue collected 6 h after administration of D9- choline and U13C-DPPC–containing CHF5633. Parts-per-million (ppm) mass errors are indicated in parentheses. (c) Magnification of the boxed region in (a) with selected bronchiolar regions outlined in white boxes. (d) The corresponding H&E-stained tissue section with the same selected bronchiolar regions outlined in black boxes. These data demonstrate the co-localisation of the polyunsaturated lipids PC36:4 and PC38:6 with the bronchiolar regions of the lung. All MSI images were visualised using total ion current normalisation and hotspot removal (high quantile = 99%).