M/Z: 651.5289

Hit 1 annotations: DG(16:0/20:3(8Z,11Z,14Z)-2OH(5,6)/0:0)_[M+H]+

在BioDeep NovoCell知识数据库中，参考离子总共被划分为4个级别。

Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。

Found 14 Reference Ions Near m/z 651.5289

NovoCell ID	m/z	Mass Window	Metabolite	Ranking	Anatomy Context
MSI_000006342 Reliable	651.5344	651.5343 ~ 651.5345 MzDiff: `1.1 ppm`	DG(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0) (BioDeep_00000028515) Formula: C43H72O5 (668.5379)	7.76 (100%)	Rattus norvegicus [UBERON:0004358] caput epididymis
MSI_000061144 Reliable	651.5344	651.5342 ~ 651.5349 MzDiff: `3.0 ppm`	DG(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0) (BioDeep_00000028515) Formula: C43H72O5 (668.5379)	6.83 (100%)	Mus musculus [UBERON:0000956] cerebral cortex
MSI_000058617 Unreliable	651.5346	651.5342 ~ 651.5349 MzDiff: `2.7 ppm`	DG(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0) (BioDeep_00000028515) Formula: C43H72O5 (668.5379)	1.65 (100%)	Mus musculus [UBERON:0001950] neocortex
MSI_000022054 Unreliable	651.5368	651.5368 ~ 651.5368 MzDiff: `none`	SM(d18:0/12:0) (BioDeep_00000032507) Formula: C35H75N2O6P (650.5362)	0.47 (100%)	Mus musculus [UBERON:0001499] muscle of arm
MSI_000002565 Unreliable	651.5352	651.5352 ~ 651.5352 MzDiff: `none`	DG(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0) (BioDeep_00000028515) Formula: C43H72O5 (668.5379)	0.35 (100%)	Rattus norvegicus [UBERON:0001950] neocortex
MSI_000003168 Unreliable	651.5352	651.5352 ~ 651.5352 MzDiff: `none`	DG(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0) (BioDeep_00000028515) Formula: C43H72O5 (668.5379)	1.55 (100%)	Rattus norvegicus [UBERON:0002037] cerebellum
MSI_000003929 Unreliable	651.5342	651.5342 ~ 651.5342 MzDiff: `none`	DG(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0) (BioDeep_00000028515) Formula: C43H72O5 (668.5379)	1.32 (100%)	Homo sapiens [UBERON:0002107] liver
MSI_000005367 Unavailable	651.5352	651.5352 ~ 651.5352 MzDiff: `none`	DG(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0) (BioDeep_00000028515) Formula: C43H72O5 (668.5379)	-1.27 (100%)	Rattus norvegicus [UBERON:0002298] brainstem
MSI_000005598 Unreliable	651.5352	651.5352 ~ 651.5352 MzDiff: `none`	DG(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0) (BioDeep_00000028515) Formula: C43H72O5 (668.5379)	0.08 (100%)	Rattus norvegicus [UBERON:0002435] striatum
MSI_000028744 Unreliable	651.5367	651.5367 ~ 651.5367 MzDiff: `none`	Not Annotated	0.45 (0%)	Macropus giganteus [UBERON:0001891] midbrain
MSI_000030736 Unreliable	651.5367	651.5367 ~ 651.5367 MzDiff: `none`	Not Annotated	1.12 (0%)	Macropus giganteus [UBERON:0003027] cingulate cortex
MSI_000030767 Unreliable	651.5309	651.5309 ~ 651.5309 MzDiff: `none`	DG(16:0/20:3(8Z,11Z,14Z)-2OH(5,6)/0:0) (BioDeep_00000220478) Formula: C39H70O7 (650.5121)	1.05 (100%)	Macropus giganteus [UBERON:0003027] cingulate cortex
MSI_000059987 Unavailable	651.5347	651.5347 ~ 651.5347 MzDiff: `none`	DG(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0) (BioDeep_00000028515) Formula: C43H72O5 (668.5379)	-0.78 (100%)	Mus musculus [UBERON:0002298] brainstem
MSI_000060603 Unavailable	651.5347	651.5347 ~ 651.5347 MzDiff: `none`	DG(18:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)/0:0) (BioDeep_00000028515) Formula: C43H72O5 (668.5379)	-0.34 (100%)	Mus musculus [UBERON:0002421] hippocampal formation

Found 2 Sample Hits

Metabolite	Species	Sample
DG(16:0/20:3(8Z,11Z,14Z)-2OH(5,6)/0:0) Formula: C39H70O7 (650.5121) Adducts: [M+H]+ (Ppm: 14.6)	Mus musculus (Lung)	image2 Resolution: 40μm, 550x256 Description Supplementary Figure S6. Ion distribution images for (a) [PC36:4+Na]+ (m/z 804.5514) and (b) [PC38:6+Na]+ (m/z 828.5515) obtained from mouse lung tissue collected 6 h after administration of D9- choline and U13C-DPPC–containing CHF5633. Parts-per-million (ppm) mass errors are indicated in parentheses. (c) Magnification of the boxed region in (a) with selected bronchiolar regions outlined in white boxes. (d) The corresponding H&E-stained tissue section with the same selected bronchiolar regions outlined in black boxes. These data demonstrate the co-localisation of the polyunsaturated lipids PC36:4 and PC38:6 with the bronchiolar regions of the lung. All MSI images were visualised using total ion current normalisation and hotspot removal (high quantile = 99%).
DG(16:0/20:3(8Z,11Z,14Z)-2OH(5,6)/0:0) Formula: C39H70O7 (650.5121) Adducts: [M+H]+ (Ppm: 17.6)	Macropus giganteus (Brain)	170321_kangaroobrain-dan3-pos_maxof50.0_med1 Resolution: 50μm, 81x50 Description Sample information Organism: Macropus giganteus (kangaroo) Organism part: Brain Condition: Wildtype Sample growth conditions: Wild

Metabolite

Species

Sample

DG(16:0/20:3(8Z,11Z,14Z)-2OH(5,6)/0:0)

Formula: C39H70O7 (650.5121)
Adducts: [M+H]+ (Ppm: 14.6)

Mus musculus (Lung)

image2

Resolution: 40μm, 550x256

Description

Supplementary Figure S6. Ion distribution images for (a) [PC36:4+Na]+ (m/z 804.5514) and (b) [PC38:6+Na]+ (m/z 828.5515) obtained from mouse lung tissue collected 6 h after administration of D9- choline and U13C-DPPC–containing CHF5633. Parts-per-million (ppm) mass errors are indicated in parentheses. (c) Magnification of the boxed region in (a) with selected bronchiolar regions outlined in white boxes. (d) The corresponding H&E-stained tissue section with the same selected bronchiolar regions outlined in black boxes. These data demonstrate the co-localisation of the polyunsaturated lipids PC36:4 and PC38:6 with the bronchiolar regions of the lung. All MSI images were visualised using total ion current normalisation and hotspot removal (high quantile = 99%).

DG(16:0/20:3(8Z,11Z,14Z)-2OH(5,6)/0:0)

Formula: C39H70O7 (650.5121)
Adducts: [M+H]+ (Ppm: 17.6)

Macropus giganteus (Brain)

170321_kangaroobrain-dan3-pos_maxof50.0_med1

Resolution: 50μm, 81x50

Description

Sample information Organism: Macropus giganteus (kangaroo) Organism part: Brain Condition: Wildtype Sample growth conditions: Wild