- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。
Found 6 Reference Ions Near m/z 585.3052
| NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
|---|---|---|---|---|---|
| MSI_000021065 Reliable | 585.3146 | 585.3141 ~ 585.3147 MzDiff: 2.1 ppm |
Amikacin (BioDeep_00000003438) Formula: C22H43N5O13 (585.2857) |
6.01 (100%) | Rattus norvegicus [UBERON:0004358] caput epididymis |
| MSI_000006617 | 585.2969 | 585.2969 ~ 585.2969 MzDiff: none |
Ouabain (BioDeep_00000002362) Formula: C29H44O12 (584.2833) |
3.31 (100%) | Rattus norvegicus [UBERON:0004358] caput epididymis |
| MSI_000010036 Unreliable | 585.3149 | 585.3149 ~ 585.3149 MzDiff: 0.1 ppm |
Amikacin (BioDeep_00000003438) Formula: C22H43N5O13 (585.2857) |
0.67 (100%) | Bathymodiolus [UBERON:0009120] gill filament |
| MSI_000011795 Unreliable | 585.3149 | 585.3149 ~ 585.3149 MzDiff: none |
Amikacin (BioDeep_00000003438) Formula: C22H43N5O13 (585.2857) |
1.33 (100%) | Bathymodiolus [UBERON:2000211] gill lamella |
| MSI_000003740 Unreliable | 585.3052 | 585.3052 ~ 585.3052 MzDiff: none |
Tigecycline (BioDeep_00000014658) Formula: C29H39N5O8 (585.2798) |
1.71 (100%) | Homo sapiens [UBERON:0002107] liver |
| MSI_000024319 Unreliable | 585.2969 | 585.2969 ~ 585.2969 MzDiff: none |
Tigecycline (BioDeep_00000014658) Formula: C29H39N5O8 (585.2798) |
1.79 (100%) | Mus musculus [UBERON:0004269] upper arm connective tissue |
Found 6 Sample Hits
| Metabolite | Species | Sample | |
|---|---|---|---|
| Tigecycline Formula: C29H39N5O8 (585.2798) Adducts: [M-H2O+NH4]+ (Ppm: 3.6) |
Homo sapiens (Liver) |
20171107_FIT4_DHBpos_p70_s50Resolution: 50μm, 70x70
|
|
| Amikacin Formula: C22H43N5O13 (585.2857) Adducts: [M-H2O+NH4]+ (Ppm: 5.8) |
Mus musculus (Lung) |
image1Resolution: 40μm, 187x165
Fig. 2 MALDI-MSI data from the same mouse lung tissue analyzed in Fig. 1. A: Optical image of the post-MSI, H&E-stained tissue section. B–D, F–G: Ion images of (B) m/z 796.6855 ([U13C-DPPC+Na]+), (C) m/z 756.5514 ([PC32:0+Na]+), (D) m/z 765.6079 ([D9-PC32:0+Na]+), (F) m/z 754.5359 ([PC32:1+Na]+), and (G) m/z 763.5923 ([D9-PC32:1+Na]+). E, H: Ratio images of (E) [D9-PC32:0+Na]+:[PC32:0+Na]+ and (H) [D9-PC32:1+Na]+:[PC32:1+Na]+. Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. U13C-DPPC, universally 13C-labeled dipalmitoyl PC; PC, phosphatidylcholine; MSI, mass spectrometry imaging; H&E, hematoxylin and eosin.
Fig 1-3, Fig S1-S3, S5 |
|
| Tigecycline Formula: C29H39N5O8 (585.2798) Adducts: [M-H2O+NH4]+ (Ppm: 10.6) |
Mus musculus (Left upper arm) |
357_l_total ion countResolution: 50μm, 97x131
Diseased |
|
| Tigecycline Formula: C29H39N5O8 (585.2798) Adducts: [M-H2O+NH4]+ (Ppm: 0.4) |
Homo sapiens (esophagus) |
LNTO22_1_4Resolution: 17μm, 82x80
|
|
| Tigecycline Formula: C29H39N5O8 (585.2798) Adducts: [M-H2O+NH4]+ (Ppm: 7.4) |
Homo sapiens (colorectal adenocarcinoma) |
80TopL, 50TopR, 70BottomL, 60BottomR-profileResolution: 17μm, 137x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| Tigecycline Formula: C29H39N5O8 (585.2798) Adducts: [M-H2O+NH4]+ (Ppm: 6.3) |
Homo sapiens (NA) |
160TopL,130TopR,150BottomL,140BottomR-profileResolution: 17μm, 142x136
|
|
