在BioDeep NovoCell知识数据库中,参考离子总共被划分为4个级别。
  • Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
  • Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
  • Unreliable: 这个参考离子具有较高的排名价值,但缺乏可重复性。
  • Unavailable: 由于排名价值低且缺乏可重复性,这个参考离子不应用于注释。

Found 5 Reference Ions Near m/z 573.4755
NovoCell ID m/z Mass Window Metabolite Ranking Anatomy Context
MSI_000065346 Unreliable 573.4847 573.4845 ~ 573.4849
MzDiff: 1.5 ppm
Dieporeticenin (BioDeep_00000023923)
Formula: C37H64O4 (572.4804)
3.61 (100%) Homo sapiens
[UBERON:0001155] colon
MSI_000027225 Unreliable 573.4852 573.4852 ~ 573.4852
MzDiff: none
Dieporeticenin (BioDeep_00000023923)
Formula: C37H64O4 (572.4804)
2.03 (100%) Mus musculus
[UBERON:0002048] lung
MSI_000058462 Unreliable 573.4854 573.4854 ~ 573.4854
MzDiff: none
Dieporeticenin (BioDeep_00000023923)
Formula: C37H64O4 (572.4804)
1.15 (100%) Mus musculus
[UBERON:0001950] neocortex
MSI_000059815 Unavailable 573.4854 573.4854 ~ 573.4854
MzDiff: none
Dieporeticenin (BioDeep_00000023923)
Formula: C37H64O4 (572.4804)
-0.6 (100%) Mus musculus
[UBERON:0002298] brainstem
MSI_000060900 Unavailable 573.4854 573.4854 ~ 573.4854
MzDiff: none
Dieporeticenin (BioDeep_00000023923)
Formula: C37H64O4 (572.4804)
-0.55 (100%) Mus musculus
[UBERON:0002421] hippocampal formation

Found 5 Sample Hits
Metabolite Species Sample
Dieporeticenin

Formula: C37H64O4 (572.4804)
Adducts: [M+H]+ (Ppm: 5.9)
Mus musculus (Lung)
image4
Resolution: 40μm, 162x156

Description

Fig 6c Fig. 6 MALDI-MSI of U13C-PC16:0/16:0 acyl chain remodeling. A: Averaged MALDI mass spectrum from lung tissue collected from mice euthanized 12 h after administration of D9-choline and U13C-DPPC–containing Poractant alfa surfactant. The ion at m/z 828.6321 is assigned as the [M+Na]+ ion of 13C24-PC16:0_20:4 formed by acyl remodeling of U13C-PC16:0/16:0. The “NL” value refers to the intensity of the base peak in the full range MS1 spectrum. B: MS/MS spectrum of precursor ions at m/z 828.5 ± 0.5 with fragment ions originating from [13C24-PC16:0_20:4+Na]+ annotated. Part-per-million (ppm) mass errors are provided in parentheses. C, D: MALDI-MSI data of [U13C-DPPC+Na]+ (blue), [PC36:4+Na]+ (green) and [13C24-PC16:0_20:4+Na]+ (red) in lung tissue collected from mice (C) 12 h and (D) 18 h after label administration. All images were visualized using total-ion-current normalization and hotspot removal (high quantile = 99%). MS/MS, tandem mass spectrometry; MSI, mass spectrometry imaging; PC, phosphatidylcholine; U13C-DPPC, universally 13C-labeled dipalmitoyl PC.

Dieporeticenin

Formula: C37H64O4 (572.4804)
Adducts: [M+H]+ (Ppm: 4.4)
Mus musculus (Lung)
image2
Resolution: 40μm, 550x256

Description

Supplementary Figure S6. Ion distribution images for (a) [PC36:4+Na]+ (m/z 804.5514) and (b) [PC38:6+Na]+ (m/z 828.5515) obtained from mouse lung tissue collected 6 h after administration of D9- choline and U13C-DPPC–containing CHF5633. Parts-per-million (ppm) mass errors are indicated in parentheses. (c) Magnification of the boxed region in (a) with selected bronchiolar regions outlined in white boxes. (d) The corresponding H&E-stained tissue section with the same selected bronchiolar regions outlined in black boxes. These data demonstrate the co-localisation of the polyunsaturated lipids PC36:4 and PC38:6 with the bronchiolar regions of the lung. All MSI images were visualised using total ion current normalisation and hotspot removal (high quantile = 99%).

Dieporeticenin

Formula: C37H64O4 (572.4804)
Adducts: [M+H]+ (Ppm: 8.6)
Macropus giganteus (Brain)
170321_kangaroobrain-dan3-pos_maxof50.0_med1
Resolution: 50μm, 81x50

Description

Sample information Organism: Macropus giganteus (kangaroo) Organism part: Brain Condition: Wildtype Sample growth conditions: Wild

Pancuronium

Formula: C35H60N2O4 (572.4553)
Adducts: [M+H]+ (Ppm: 17)
Homo sapiens (colorectal adenocarcinoma)
520TopL, 490TopR, 510BottomL, 500BottomR-profile
Resolution: 17μm, 147x131

Description

The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024).

7,8-Dihydroparasiloxanthin

Formula: C40H60O2 (572.4593)
Adducts: [M+H]+ (Ppm: 15.6)
Homo sapiens (colorectal adenocarcinoma)
439TopL, 409TopR, 429BottomL, 419BottomR-profile
Resolution: 17μm, 157x136

Description

The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024).