- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。
Found 11 Reference Ions Near m/z 540.0594
| NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
|---|---|---|---|---|---|
| MSI_000053616 Reliable | 540.0663 | 540.0661 ~ 540.067 MzDiff: 3.8 ppm |
4,12-dihydroxy-10-{[4'-(sulfooxy)-[1,1'-biphenyl]-3,3'-diyl]oxy}-8-oxatricyclo[7.4.0.0²,⁷]trideca-1(9),2(7),3,5,10,12-hexaene-5-carboxylic acid (BioDeep_00002280238) Formula: C25H16O12S (540.0362) |
7.18 (89%) | MALDI - CHCA [NOVOCELL:BACKGROUND] blank |
| MSI_000010498 Unavailable | 540.0664 | 540.0664 ~ 540.0664 MzDiff: 0.2 ppm |
Alamifovir (BioDeep_00000175819) Formula: C19H20F6N5O5PS (575.0827) |
-1.59 (100%) | Bathymodiolus [UBERON:0009120] gill filament |
| MSI_000054854 Unreliable | 540.0667 | 540.0662 ~ 540.067 MzDiff: 3.1 ppm |
Alamifovir (BioDeep_00000175819) Formula: C19H20F6N5O5PS (575.0827) |
1.69 (100%) | MALDI - DHB [NOVOCELL:BACKGROUND] blank |
| MSI_000012249 Unavailable | 540.0664 | 540.0664 ~ 540.0664 MzDiff: 0.0 ppm |
Alamifovir (BioDeep_00000175819) Formula: C19H20F6N5O5PS (575.0827) |
-1.06 (100%) | Bathymodiolus [UBERON:2000211] gill lamella |
| MSI_000012845 Unavailable | 540.068 | 540.068 ~ 540.068 MzDiff: none |
Alamifovir (BioDeep_00000175819) Formula: C19H20F6N5O5PS (575.0827) |
-0.49 (100%) | Plant [PO:0005020] vascular bundle |
| MSI_000014084 Unavailable | 540.068 | 540.068 ~ 540.068 MzDiff: none |
Alamifovir (BioDeep_00000175819) Formula: C19H20F6N5O5PS (575.0827) |
-0.3 (100%) | Plant [PO:0005417] phloem |
| MSI_000014935 Unavailable | 540.068 | 540.068 ~ 540.068 MzDiff: none |
Alamifovir (BioDeep_00000175819) Formula: C19H20F6N5O5PS (575.0827) |
-0.49 (100%) | Plant [PO:0006036] root epidermis |
| MSI_000018343 Unreliable | 540.068 | 540.068 ~ 540.068 MzDiff: none |
Alamifovir (BioDeep_00000175819) Formula: C19H20F6N5O5PS (575.0827) |
1.78 (100%) | Plant [PO:0020124] root stele |
| MSI_000019940 Unavailable | 540.068 | 540.068 ~ 540.068 MzDiff: none |
Alamifovir (BioDeep_00000175819) Formula: C19H20F6N5O5PS (575.0827) |
-0.5 (100%) | Plant [PO:0025197] stele |
| MSI_000051464 Unreliable | 540.0662 | 540.0662 ~ 540.0662 MzDiff: none |
Alamifovir (BioDeep_00000175819) Formula: C19H20F6N5O5PS (575.0827) |
0 (100%) | Mytilus edulis [UBERON:2001856] gill ray |
| MSI_000065860 Unreliable | 540.054 | 540.054 ~ 540.054 MzDiff: none |
I-Abopx (BioDeep_00000179890) Formula: C23H22IN5O5 (575.0666) |
1.62 (100%) | Homo sapiens [UBERON:0007779] transudate |
Found 9 Sample Hits
| Metabolite | Species | Sample | |
|---|---|---|---|
| Alamifovir Formula: C19H20F6N5O5PS (575.0827) Adducts: [M+H-2H2O]+ (Ppm: 10.3) |
Mus musculus (Lung) |
image4Resolution: 40μm, 162x156
Fig 6c
Fig. 6 MALDI-MSI of U13C-PC16:0/16:0 acyl chain remodeling. A: Averaged MALDI mass spectrum from lung tissue collected from mice euthanized 12 h after administration of D9-choline and U13C-DPPC–containing Poractant alfa surfactant. The ion at m/z 828.6321 is assigned as the [M+Na]+ ion of 13C24-PC16:0_20:4 formed by acyl remodeling of U13C-PC16:0/16:0. The “NL” value refers to the intensity of the base peak in the full range MS1 spectrum. B: MS/MS spectrum of precursor ions at m/z 828.5 ± 0.5 with fragment ions originating from [13C24-PC16:0_20:4+Na]+ annotated. Part-per-million (ppm) mass errors are provided in parentheses. C, D: MALDI-MSI data of [U13C-DPPC+Na]+ (blue), [PC36:4+Na]+ (green) and [13C24-PC16:0_20:4+Na]+ (red) in lung tissue collected from mice (C) 12 h and (D) 18 h after label administration. All images were visualized using total-ion-current normalization and hotspot removal (high quantile = 99%). MS/MS, tandem mass spectrometry; MSI, mass spectrometry imaging; PC, phosphatidylcholine; U13C-DPPC, universally 13C-labeled dipalmitoyl PC. |
|
| Alamifovir Formula: C19H20F6N5O5PS (575.0827) Adducts: [M+H-2H2O]+ (Ppm: 17.5) |
Homo sapiens (colorectal adenocarcinoma) |
80TopL, 50TopR, 70BottomL, 60BottomR-profileResolution: 17μm, 137x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| I-Abopx Formula: C23H22IN5O5 (575.0666) Adducts: [M+H-2H2O]+ (Ppm: 16.5) |
Mytilus edulis (mantle) |
20190201_MS38_Crassostrea_Mantle_350-1500_DHB_pos_A28_10um_270x210Resolution: 10μm, 270x210
|
|
| I-Abopx Formula: C23H22IN5O5 (575.0666) Adducts: [M+H-2H2O]+ (Ppm: 15.4) |
Mytilus edulis (gill) |
20190202_MS38_Crassostrea_Gill_350-1500_DHB_pos_A25_11um_305x210Resolution: 11μm, 305x210
single cell layer |
|
| I-Abopx Formula: C23H22IN5O5 (575.0666) Adducts: [M+H-2H2O]+ (Ppm: 15.5) |
Mytilus edulis (mantle) |
20190216_MS38_Mytilus_mantle_350-1500_DHB_pos_A26_10um_275x210Resolution: 10μm, 275x210
|
|
| Alamifovir Formula: C19H20F6N5O5PS (575.0827) Adducts: [M+H-2H2O]+ (Ppm: 16.7) |
Homo sapiens (colorectal adenocarcinoma) |
520TopL, 490TopR, 510BottomL, 500BottomR-profileResolution: 17μm, 147x131
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| I-Abopx Formula: C23H22IN5O5 (575.0666) Adducts: [M+H-2H2O]+ (Ppm: 0.4) |
Homo sapiens (colorectal adenocarcinoma) |
439TopL, 409TopR, 429BottomL, 419BottomR-profileResolution: 17μm, 157x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| L-Alanine, N-(2,6-dichloro-4-(((3-(2-furanyl)-1-oxo-2-propenyl)amino)methyl)benzoyl)-3-(((4R)-4-thiazolidinylcarbonyl)amino)- Formula: C22H22Cl2N4O6S (540.0637) Adducts: [M]+ (Ppm: 2.3) |
Homo sapiens (colorectal adenocarcinoma) |
439TopL, 409TopR, 429BottomL, 419BottomR-profileResolution: 17μm, 157x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| I-Abopx Formula: C23H22IN5O5 (575.0666) Adducts: [M+H-2H2O]+ (Ppm: 7) |
Homo sapiens (NA) |
160TopL,130TopR,150BottomL,140BottomR-profileResolution: 17μm, 142x136
|
|
