M/Z: 533.0754

Hit 2 annotations: 6-[2-(6-chloroquinolin-2-yl)-1,3-thiazol-4-yl]-n-(2-hydroxyethyl)-3-methanesulfinyl-5-methoxy-1-methyl-4-oxopyridine-2-carboximidic acid_[M+H]+; cefsulodin_[M+H]+

在BioDeep NovoCell知识数据库中，参考离子总共被划分为4个级别。

Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。

Found 2 Reference Ions Near m/z 533.0754

NovoCell ID	m/z	Mass Window	Metabolite	Ranking	Anatomy Context
MSI_000027437 Unreliable	533.0783	533.0783 ~ 533.0783 MzDiff: `none`	cefsulodin (BioDeep_00000177126) Formula: C22H20N4O8S2 (532.0723)	2 (100%)	Mus musculus [UBERON:0000913] interstitial fluid
MSI_000051301 Unreliable	533.0845	533.0845 ~ 533.0845 MzDiff: `none`	cefsulodin (BioDeep_00000008564) Formula: C22H20N4O8S2 (532.0723)	0 (100%)	Mytilus edulis [UBERON:2001856] gill ray

Found 3 Sample Hits

Metabolite	Species	Sample
6-[2-(6-chloroquinolin-2-yl)-1,3-thiazol-4-yl]-n-(2-hydroxyethyl)-3-methanesulfinyl-5-methoxy-1-methyl-4-oxopyridine-2-carboximidic acid Formula: C23H21ClN4O5S2 (532.0642) Adducts: [M+H]+ (Ppm: 7.4)	Vitis vinifera (Fruit)	grape_dhb_91_1 Resolution: 50μm, 120x114 Description Grape berries fruit, condition: Ripe
cefsulodin Formula: C22H20N4O8S2 (532.0723) Adducts: [M+H]+ (Ppm: 2.3)	Mus musculus (Lung)	image2 Resolution: 40μm, 550x256 Description Supplementary Figure S6. Ion distribution images for (a) [PC36:4+Na]+ (m/z 804.5514) and (b) [PC38:6+Na]+ (m/z 828.5515) obtained from mouse lung tissue collected 6 h after administration of D9- choline and U13C-DPPC–containing CHF5633. Parts-per-million (ppm) mass errors are indicated in parentheses. (c) Magnification of the boxed region in (a) with selected bronchiolar regions outlined in white boxes. (d) The corresponding H&E-stained tissue section with the same selected bronchiolar regions outlined in black boxes. These data demonstrate the co-localisation of the polyunsaturated lipids PC36:4 and PC38:6 with the bronchiolar regions of the lung. All MSI images were visualised using total ion current normalisation and hotspot removal (high quantile = 99%).
cefsulodin Formula: C22H20N4O8S2 (532.0723) Adducts: [M+H]+ (Ppm: 0.1)	Homo sapiens (esophagus)	LNTO22_1_5 Resolution: 75μm, 135x94 Description

Metabolite

Species

Sample

6-[2-(6-chloroquinolin-2-yl)-1,3-thiazol-4-yl]-n-(2-hydroxyethyl)-3-methanesulfinyl-5-methoxy-1-methyl-4-oxopyridine-2-carboximidic acid

Formula: C23H21ClN4O5S2 (532.0642)
Adducts: [M+H]+ (Ppm: 7.4)

Vitis vinifera (Fruit)

grape_dhb_91_1

Resolution: 50μm, 120x114

Description

Grape berries fruit, condition: Ripe

cefsulodin

Formula: C22H20N4O8S2 (532.0723)
Adducts: [M+H]+ (Ppm: 2.3)

Mus musculus (Lung)

image2

Resolution: 40μm, 550x256

Description

Supplementary Figure S6. Ion distribution images for (a) [PC36:4+Na]+ (m/z 804.5514) and (b) [PC38:6+Na]+ (m/z 828.5515) obtained from mouse lung tissue collected 6 h after administration of D9- choline and U13C-DPPC–containing CHF5633. Parts-per-million (ppm) mass errors are indicated in parentheses. (c) Magnification of the boxed region in (a) with selected bronchiolar regions outlined in white boxes. (d) The corresponding H&E-stained tissue section with the same selected bronchiolar regions outlined in black boxes. These data demonstrate the co-localisation of the polyunsaturated lipids PC36:4 and PC38:6 with the bronchiolar regions of the lung. All MSI images were visualised using total ion current normalisation and hotspot removal (high quantile = 99%).

cefsulodin

Formula: C22H20N4O8S2 (532.0723)
Adducts: [M+H]+ (Ppm: 0.1)

Homo sapiens (esophagus)

LNTO22_1_5

Resolution: 75μm, 135x94

Description