M/Z: 492.9697

Hit 1 annotations: patuletin 3,3'-di-o-sulfate_[M+H]+

在BioDeep NovoCell知识数据库中，参考离子总共被划分为4个级别。

Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。

Found 11 Reference Ions Near m/z 492.9697

NovoCell ID	m/z	Mass Window	Metabolite	Ranking	Anatomy Context
MSI_000011422 Unreliable	492.9642	492.9642 ~ 492.9642 MzDiff: `none`	Rosmarinic acid (BioDeep_00000419013) Formula: C20H11BrClF3N4O2 (509.9706)	0.43 (100%)	Mus musculus [UBERON:0012378] muscle layer of urinary bladder
MSI_000011376 Unreliable	492.9697	492.9697 ~ 492.9697 MzDiff: `none`	patuletin 3,3'-di-o-sulfate (BioDeep_00002254960) Formula: C16H12O14S2 (491.9668)	0.68 (100%)	Mus musculus [UBERON:0012378] muscle layer of urinary bladder
MSI_000061163 Unreliable	492.9605	492.9605 ~ 492.9605 MzDiff: `0.0 ppm`	Not Annotated	1.74 (%)	Mus musculus [UBERON:0000956] cerebral cortex
MSI_000009802 Unavailable	492.9697	492.9697 ~ 492.9697 MzDiff: `none`	patuletin 3,3'-di-o-sulfate (BioDeep_00002254960) Formula: C16H12O14S2 (491.9668)	-1.69 (100%)	Mus musculus [UBERON:0004645] urinary bladder urothelium
MSI_000059695 Unreliable	492.9601	492.9601 ~ 492.9601 MzDiff: `none`	Not Annotated	0.61 (%)	Mus musculus [UBERON:0002298] brainstem
MSI_000002967 Unavailable	492.9626	492.9626 ~ 492.9626 MzDiff: `none`	N-Methyl-14-bromo-1-hydroxy-7,8-dehydrodiscorhabdin V (+2) (BioDeep_00000409015) Formula: [C19H16Br2N3O3]+ (491.9558)	-0.71 (100%)	Rattus norvegicus [UBERON:0001950] neocortex
MSI_000003521 Unavailable	492.9626	492.9626 ~ 492.9626 MzDiff: `none`	N-Methyl-14-bromo-1-hydroxy-7,8-dehydrodiscorhabdin V (+2) (BioDeep_00000409015) Formula: [C19H16Br2N3O3]+ (491.9558)	-0.53 (100%)	Rattus norvegicus [UBERON:0002037] cerebellum
MSI_000005219 Unavailable	492.9626	492.9626 ~ 492.9626 MzDiff: `none`	N-Methyl-14-bromo-1-hydroxy-7,8-dehydrodiscorhabdin V (+2) (BioDeep_00000409015) Formula: [C19H16Br2N3O3]+ (491.9558)	-0.74 (100%)	Rattus norvegicus [UBERON:0002298] brainstem
MSI_000005534 Unreliable	492.9626	492.9626 ~ 492.9626 MzDiff: `none`	N-Methyl-14-bromo-1-hydroxy-7,8-dehydrodiscorhabdin V (+2) (BioDeep_00000409015) Formula: [C19H16Br2N3O3]+ (491.9558)	1.36 (100%)	Rattus norvegicus [UBERON:0002435] striatum
MSI_000000130 Unreliable	492.9642	492.9642 ~ 492.9642 MzDiff: `none`	Rosmarinic acid (BioDeep_00000419013) Formula: C20H11BrClF3N4O2 (509.9706)	1.97 (100%)	Mus musculus [CL:0000066] epithelial cell
MSI_000000099 Unreliable	492.9697	492.9697 ~ 492.9697 MzDiff: `none`	patuletin 3,3'-di-o-sulfate (BioDeep_00002254960) Formula: C16H12O14S2 (491.9668)	2.05 (100%)	Mus musculus [CL:0000066] epithelial cell

Found 2 Sample Hits

Metabolite	Species	Sample
patuletin 3,3'-di-o-sulfate Formula: C16H12O14S2 (491.9668) Adducts: [M+H]+ (Ppm: 9)	Mus musculus (Urinary bladder)	HR2MSI_mouse_urinary_bladder - S096 Resolution: 10μm, 260x134 Description Mass spectrometry imaging of phospholipids in mouse urinary bladder (imzML dataset) The spatial distribution of phospholipids in a tissue section of mouse urinary bladder was analyzed by MALDI MS imaging at 10 micrometer pixel size with high mass resolution (using an LTQ Orbitrap mass spectrometer). R, ö, mpp A, Guenther S, Schober Y, Schulz O, Takats Z, Kummer W, Spengler B, Histology by mass spectrometry: label-free tissue characterization obtained from high-accuracy bioanalytical imaging. Angew Chem Int Ed Engl, 49(22):3834-8(2010) Fig. S2: Single ion images of compounds shown in Fig. 1A-B : (upper left to lower right) m/z = 743.5482 (unknown), m/z = 741.5307 (SM (16:0), [M+K]+), m/z = 798.5410 (PC (34:1), [M+K]+), m/z = 616.1767 (heme b, M+), m/z = 772.5253 (PC (32:0), [M+K]+). Stability of determined mass values was in the range of +/- 1 ppm over 22 hours of measurement (Fig. S4), with a standard deviation of 0.56 ppm. Accuracy data were obtained during tissue scanning experiments by monitoring the mass signal at nominal mass 798. The internal lock mass function of the Orbitrap instrument was used for automatic calibration during imaging measurements, using the known matrix-related ion signals at m/z = 137.0233, m/z = 444.0925 and m/z = 716.1246.
m/z_492.9601 Formula: - (n/a) Adducts: (Ppm: )	Mus musculus (brain)	Brain01_Bregma-3-88b_centroid Resolution: 17μm, 265x320 Description

Metabolite

Species

Sample

patuletin 3,3'-di-o-sulfate

Formula: C16H12O14S2 (491.9668)
Adducts: [M+H]+ (Ppm: 9)

Mus musculus (Urinary bladder)

HR2MSI_mouse_urinary_bladder - S096

Resolution: 10μm, 260x134

Description

Mass spectrometry imaging of phospholipids in mouse urinary bladder (imzML dataset)
The spatial distribution of phospholipids in a tissue section of mouse urinary bladder was analyzed by MALDI MS imaging at 10 micrometer pixel size with high mass resolution (using an LTQ Orbitrap mass spectrometer).

R, ö, mpp A, Guenther S, Schober Y, Schulz O, Takats Z, Kummer W, Spengler B, Histology by mass spectrometry: label-free tissue characterization obtained from high-accuracy bioanalytical imaging. Angew Chem Int Ed Engl, 49(22):3834-8(2010)

Fig. S2: Single ion images of compounds shown in Fig. 1A-B : (upper left to lower right) m/z = 743.5482 (unknown), m/z = 741.5307 (SM (16:0), [M+K]+), m/z = 798.5410 (PC (34:1), [M+K]+), m/z = 616.1767 (heme b, M+), m/z = 772.5253 (PC (32:0), [M+K]+).

Stability of determined mass values was in the range of +/- 1 ppm over 22 hours of measurement (Fig. S4), with a standard deviation of 0.56 ppm. Accuracy data were obtained during tissue scanning experiments by monitoring the mass signal at nominal mass 798. The internal lock mass function of the Orbitrap instrument was used for automatic calibration during imaging measurements, using the known matrix-related ion signals at m/z = 137.0233, m/z = 444.0925 and m/z = 716.1246.

m/z_492.9601

Formula: - (n/a)
Adducts: (Ppm: )

Mus musculus (brain)

Brain01_Bregma-3-88b_centroid

Resolution: 17μm, 265x320

Description