M/Z: 450.3058
Hit 3 annotations: LysoPC(14:0/0:0)_[M+H-H2O]+; Buprenorphine_[M+H-H2O]+; Oxethazaine_[M+H-H2O]+
- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。
Found 3 Reference Ions Near m/z 450.3058
| NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
|---|---|---|---|---|---|
| MSI_000049797 Unreliable | 450.2976 | 450.2976 ~ 450.2976 MzDiff: none |
LysoPC(14:0/0:0) (BioDeep_00000019437) Formula: C22H46NO7P (467.3012) |
1.54 (100%) | Mytilus edulis [UBERON:0009120] gill filament |
| MSI_000050952 Unreliable | 450.2976 | 450.2976 ~ 450.2976 MzDiff: none |
LysoPC(14:0/0:0) (BioDeep_00000019437) Formula: C22H46NO7P (467.3012) |
0.51 (100%) | Mytilus edulis [UBERON:2001856] gill ray |
| MSI_000057133 Unreliable | 450.3073 | 450.3073 ~ 450.3073 MzDiff: none |
Buprenorphine (BioDeep_00000001442) Formula: C29H41NO4 (467.3035) |
1.36 (100%) | Homo sapiens [UBERON:0007779] transudate |
Found 6 Sample Hits
| Metabolite | Species | Sample | |
|---|---|---|---|
| LysoPC(14:0/0:0) Formula: C22H46NO7P (467.3012) Adducts: [M+H-H2O]+ (Ppm: 2.2) |
Mus musculus (Lung) |
image1Resolution: 40μm, 187x165
Fig. 2 MALDI-MSI data from the same mouse lung tissue analyzed in Fig. 1. A: Optical image of the post-MSI, H&E-stained tissue section. B–D, F–G: Ion images of (B) m/z 796.6855 ([U13C-DPPC+Na]+), (C) m/z 756.5514 ([PC32:0+Na]+), (D) m/z 765.6079 ([D9-PC32:0+Na]+), (F) m/z 754.5359 ([PC32:1+Na]+), and (G) m/z 763.5923 ([D9-PC32:1+Na]+). E, H: Ratio images of (E) [D9-PC32:0+Na]+:[PC32:0+Na]+ and (H) [D9-PC32:1+Na]+:[PC32:1+Na]+. Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. U13C-DPPC, universally 13C-labeled dipalmitoyl PC; PC, phosphatidylcholine; MSI, mass spectrometry imaging; H&E, hematoxylin and eosin.
Fig 1-3, Fig S1-S3, S5 |
|
| Buprenorphine Formula: C29H41NO4 (467.3035) Adducts: [M+H-H2O]+ (Ppm: 15.6) |
Homo sapiens (esophagus) |
LNTO22_1_4Resolution: 17μm, 82x80
|
|
| Oxethazaine Formula: C28H41N3O3 (467.3148) Adducts: [M+H-H2O]+ (Ppm: 12.6) |
Homo sapiens (colorectal adenocarcinoma) |
520TopL, 490TopR, 510BottomL, 500BottomR-profileResolution: 17μm, 147x131
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| LysoPC(14:0/0:0) Formula: C22H46NO7P (467.3012) Adducts: [M+H-H2O]+ (Ppm: 4) |
Homo sapiens (colorectal adenocarcinoma) |
439TopL, 409TopR, 429BottomL, 419BottomR-profileResolution: 17μm, 157x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| Oxethazaine Formula: C28H41N3O3 (467.3148) Adducts: [M+H-H2O]+ (Ppm: 9.3) |
Homo sapiens (colorectal adenocarcinoma) |
439TopL, 409TopR, 429BottomL, 419BottomR-profileResolution: 17μm, 157x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| LysoPC(14:0/0:0) Formula: C22H46NO7P (467.3012) Adducts: [M+H-H2O]+ (Ppm: 2.9) |
Homo sapiens (colorectal adenocarcinoma) |
240TopL, 210TopR, 230BottomL, 220BottomR-centroidResolution: 50μm, 142x141
|
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