M/Z: 423.188
Hit 3 annotations: 4'-Hydroxycarvedilol_[M+H]+; Neolinustatin_[M-H2O+NH4]+; Isoangustone A_[M+H]+
- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。
Found 4 Reference Ions Near m/z 423.188
| NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
|---|---|---|---|---|---|
| MSI_000052914 Reliable | 423.1825 | 423.182 ~ 423.1827 MzDiff: 2.7 ppm |
Isoangustone A (BioDeep_00000017588) Formula: C25H26O6 (422.1729) |
15 (100%) | DESI [NOVOCELL:BACKGROUND] blank |
| MSI_000052937 Reliable | 423.1807 | 423.1802 ~ 423.1809 MzDiff: 2.8 ppm |
Isoangustone A (BioDeep_00000017588) Formula: C25H26O6 (422.1729) |
5.58 (100%) | DESI [NOVOCELL:BACKGROUND] blank |
| MSI_000052996 Unreliable | 423.188 | 423.188 ~ 423.188 MzDiff: none |
4'-Hydroxycarvedilol (BioDeep_00000033159) Formula: C24H26N2O5 (422.1842) |
3.08 (100%) | DESI [NOVOCELL:BACKGROUND] blank |
| MSI_000004686 Unreliable | 423.1925 | 423.1925 ~ 423.1925 MzDiff: none |
4'-Hydroxycarvedilol (BioDeep_00000033159) Formula: C24H26N2O5 (422.1842) |
0.31 (100%) | Homo sapiens [UBERON:0002107] liver |
Found 4 Sample Hits
| Metabolite | Species | Sample | |
|---|---|---|---|
| 4'-Hydroxycarvedilol Formula: C24H26N2O5 (422.1842) Adducts: [M+H]+ (Ppm: 2.5) |
Homo sapiens (Liver) |
20171107_FIT4_DHBpos_p70_s50Resolution: 50μm, 70x70
|
|
| Neolinustatin Formula: C17H29NO11 (423.1741) Adducts: [M-H2O+NH4]+ (Ppm: 0.9) |
Mus musculus (Lung) |
image3Resolution: 40μm, 146x190
Fig. 4 MALDI-MSI data of mouse lung tissue after administration with D9-choline and U13C-DPPC–containing Poractant alfa surfactant (labels administered 12 h prior to tissue collection). Ion images of (A) m/z 796.6856 ([U13C-DPPC+Na]+), (B) m/z 756.5154 [PC32:0+Na]+), and (C) m/z 765.6079 ([D9-PC32:0+Na]+). D: Overlay image of [U13C-PC32:0+Na]+ (red) and [D9-PC32:0+Na]+ (green). Part-per-million (ppm) mass errors are indicated in parentheses. All images were visualized using total-ion-current normalization and using hotspot removal (high quantile = 99%). DPPC = PC16:0/16:0. MSI, mass spectrometry imaging; PC, phosphatidylcholine; U13C-DPPC, universally 13C-labeled dipalmitoyl PC. |
|
| 4'-Hydroxycarvedilol Formula: C24H26N2O5 (422.1842) Adducts: [M+H]+ (Ppm: 8.1) |
Homo sapiens (colorectal adenocarcinoma) |
80TopL, 50TopR, 70BottomL, 60BottomR-profileResolution: 17μm, 137x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| Isoangustone A Formula: C25H26O6 (422.1729) Adducts: [M+H]+ (Ppm: 12.7) |
Homo sapiens (colorectal adenocarcinoma) |
520TopL, 490TopR, 510BottomL, 500BottomR-profileResolution: 17μm, 147x131
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
