M/Z: 415.2345
Hit 3 annotations: Buclizine_[M+H-H2O]+; Riboflavin (Vitamin B2)_[M+K]+; p-[(R)-3-[Bis-[(R)-beta-hydroxyphenethyl]amino]butyl]benzamide_[M+H-H2O]+
- Confirmed: 这个参考离子已经通过手动审计得到确认和验证。
- Reliable: 这个参考离子可能在特定的解剖组织环境中高度保守。
- Unreliable: 这个参考离子具有较高的排名价值，但缺乏可重复性。
- Unavailable: 由于排名价值低且缺乏可重复性，这个参考离子不应用于注释。
Found 10 Reference Ions Near m/z 415.2345
| NovoCell ID | m/z | Mass Window | Metabolite | Ranking | Anatomy Context |
|---|---|---|---|---|---|
| MSI_000043158 Reliable | 415.2263 | 415.2261 ~ 415.2268 MzDiff: 2.8 ppm |
(4R,5S,7R,11x)-11,12-Dihydroxy-1(10)-spirovetiven-2-one 12-glucoside (BioDeep_00000020026) Formula: C21H34O8 (414.2254) |
14.99 (95%) | Homo sapiens [UBERON:0001043] esophagus |
| MSI_000052758 Reliable | 415.2338 | 415.2333 ~ 415.234 MzDiff: 2.7 ppm |
Riboflavin (Vitamin B2) (BioDeep_00000001427) Formula: C17H20N4O6 (376.1383) |
6.35 (100%) | DESI [NOVOCELL:BACKGROUND] blank |
| MSI_000065060 Reliable | 415.2352 | 415.235 ~ 415.2357 MzDiff: 2.8 ppm |
Riboflavin (Vitamin B2) (BioDeep_00000001427) Formula: C17H20N4O6 (376.1383) |
4.06 (100%) | DESI [NOVOCELL:BACKGROUND] blank |
| MSI_000065184 Reliable | 415.2254 | 415.2251 ~ 415.2256 MzDiff: 1.9 ppm |
(4R,5S,7R,11x)-11,12-Dihydroxy-1(10)-spirovetiven-2-one 12-glucoside (BioDeep_00000020026) Formula: C21H34O8 (414.2254) |
5.09 (100%) | Homo sapiens [UBERON:0001155] colon |
| MSI_000047668 Unreliable | 415.2261 | 415.2261 ~ 415.2261 MzDiff: none |
(4R,5S,7R,11x)-11,12-Dihydroxy-1(10)-spirovetiven-2-one 12-glucoside (BioDeep_00000020026) Formula: C21H34O8 (414.2254) |
2.18 (100%) | Homo sapiens [UBERON:0013067] colorectal mucosa |
| MSI_000051919 Unreliable | 415.2275 | 415.2275 ~ 415.2275 MzDiff: none |
(4R,5S,7R,11x)-11,12-Dihydroxy-1(10)-spirovetiven-2-one 12-glucoside (BioDeep_00000020026) Formula: C21H34O8 (414.2254) |
2.38 (100%) | Homo sapiens [UBERON:0001052] rectum |
| MSI_000052613 Unreliable | 415.2325 | 415.2325 ~ 415.2325 MzDiff: none |
Riboflavin (Vitamin B2) (BioDeep_00000001427) Formula: C17H20N4O6 (376.1383) |
1.21 (100%) | Homo sapiens [UBERON:0001052] rectum |
| MSI_000053232 Unreliable | 415.2436 | 415.2436 ~ 415.2436 MzDiff: none |
Hydrocortisone 17-butyrate (BioDeep_00000179831) Formula: C25H36O6 (432.2512) |
2.79 (100%) | DESI [NOVOCELL:BACKGROUND] blank |
| MSI_000055992 Unavailable | 415.2349 | 415.2349 ~ 415.2349 MzDiff: none |
Riboflavin (Vitamin B2) (BioDeep_00000001427) Formula: C17H20N4O6 (376.1383) |
-0.47 (100%) | Homo sapiens [UBERON:0007779] transudate |
| MSI_000056288 Unavailable | 415.2267 | 415.2267 ~ 415.2267 MzDiff: none |
Buclizine (BioDeep_00000006601) Formula: C28H33ClN2 (432.2332) |
-0.6 (100%) | Homo sapiens [UBERON:0007779] transudate |
Found 27 Sample Hits
| Metabolite | Species | Sample | |
|---|---|---|---|
| Buclizine Formula: C28H33ClN2 (432.2332) Adducts: [M+H-H2O]+ (Ppm: 19.6) |
Mus musculus (Lung) |
image2Resolution: 40μm, 550x256
Supplementary Figure S6. Ion distribution images for (a) [PC36:4+Na]+ (m/z 804.5514) and (b)
[PC38:6+Na]+ (m/z 828.5515) obtained from mouse lung tissue collected 6 h after administration of D9-
choline and U13C-DPPC–containing CHF5633. Parts-per-million (ppm) mass errors are indicated in
parentheses. (c) Magnification of the boxed region in (a) with selected bronchiolar regions outlined in
white boxes. (d) The corresponding H&E-stained tissue section with the same selected bronchiolar
regions outlined in black boxes. These data demonstrate the co-localisation of the polyunsaturated lipids
PC36:4 and PC38:6 with the bronchiolar regions of the lung. All MSI images were visualised using
total ion current normalisation and hotspot removal (high quantile = 99%). |
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 3.7) |
Homo sapiens (esophagus) |
LNTO22_1_3Resolution: 75μm, 121x68
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 5.4) |
Homo sapiens (esophagus) |
LNTO22_1_4Resolution: 17μm, 82x80
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 4.9) |
Homo sapiens (esophagus) |
LNTO29_16_2Resolution: 17μm, 95x101
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 2.5) |
Homo sapiens (esophagus) |
LNTO22_1_9Resolution: 75μm, 89x74
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 6.6) |
Homo sapiens (esophagus) |
TO39TResolution: 17μm, 69x81
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 2.2) |
Homo sapiens (colorectal adenocarcinoma) |
80TopL, 50TopR, 70BottomL, 60BottomR-profileResolution: 17μm, 137x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| p-[(R)-3-[Bis-[(R)-beta-hydroxyphenethyl]amino]butyl]benzamide Formula: C27H32N2O3 (432.2413) Adducts: [M+H-H2O]+ (Ppm: 0.7) |
Homo sapiens (colorectal adenocarcinoma) |
520TopL, 490TopR, 510BottomL, 500BottomR-profileResolution: 17μm, 147x131
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 8.5) |
Homo sapiens (colorectal adenocarcinoma) |
439TopL, 409TopR, 429BottomL, 419BottomR-profileResolution: 17μm, 157x136
The human colorectal adenocarcinoma sample was excised during a surgical operation performed at the Imperial College Healthcare NHS Trust. The sample and procedures were carried out in accordance with ethical approval (14/EE/0024). |
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 9) |
Homo sapiens (NA) |
160TopL,130TopR,150BottomL,140BottomR-profileResolution: 17μm, 142x136
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 5.4) |
Homo sapiens (esophagus) |
LNTO29_16_3Resolution: 17μm, 108x107
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 3.7) |
Homo sapiens (esophagus) |
LNTO26_7_1Resolution: 17μm, 75x74
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 2.7) |
Homo sapiens (esophagus) |
LNTO26_7_2Resolution: 17μm, 135x101
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 3.9) |
Homo sapiens (esophagus) |
LNTO26_7_3Resolution: 75μm, 82x88
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 4.2) |
Homo sapiens (esophagus) |
TO31TResolution: 75μm, 56x54
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 2.7) |
Homo sapiens (esophagus) |
TO29TResolution: 75μm, 56x48
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 4.6) |
Homo sapiens (esophagus) |
LNTO30_8M_5Resolution: 75μm, 56x54
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 3.2) |
Homo sapiens (esophagus) |
LNTO22_1_5Resolution: 75μm, 135x94
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 3.4) |
Homo sapiens (esophagus) |
LNTO22_1_7Resolution: 75μm, 69x54
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 3.9) |
Homo sapiens (esophagus) |
LNTO22_1_8Resolution: 75μm, 69x61
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 3.9) |
Homo sapiens (esophagus) |
LNTO22_2_1Resolution: 75μm, 89x88
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 0.8) |
Homo sapiens (esophagus) |
LNTO22_2_2Resolution: 75μm, 135x94
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 3.7) |
Homo sapiens (esophagus) |
LNTO26_16_1Resolution: 75μm, 95x88
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 4.9) |
Homo sapiens (esophagus) |
LNTO30_7_2Resolution: 75μm, 82x68
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 5.9) |
Homo sapiens (colorectal adenocarcinoma) |
240TopL, 210TopR, 230BottomL, 220BottomR-centroidResolution: 50μm, 142x141
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 5.9) |
Homo sapiens (colorectal adenocarcinoma) |
160TopL,130TopR,150BottomL,140BottomR-centroidResolution: 50μm, 142x136
|
|
| Riboflavin (Vitamin B2) Formula: C17H20N4O6 (376.1383) Adducts: [M+K]+ (Ppm: 5.1) |
Homo sapiens (colorectal adenocarcinoma) |
120TopL, 90TopR, 110BottomL, 100BottomR-centroidResolution: 50μm, 132x136
|
|
